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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CARD9
Full Name:
Caspase recruitment domain-containing protein 9
Alias:
Caspase recruitment domain family, member 9
Type:
Adaptor/scaffold
Mass (Da):
62240
Number AA:
UniProt ID:
Q9H257
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0050700
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0043123
GO:0046330
GO:0032874
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
E
G
F
R
V
T
L
T
S
V
I
D
P
S
R
Site 2
T31
V
I
D
P
S
R
I
T
P
Y
L
R
Q
C
K
Site 3
Y33
D
P
S
R
I
T
P
Y
L
R
Q
C
K
V
L
Site 4
S50
D
D
E
E
Q
V
L
S
D
P
N
L
V
I
R
Site 5
Y76
Q
R
T
G
H
K
G
Y
V
A
F
L
E
S
L
Site 6
S82
G
Y
V
A
F
L
E
S
L
E
L
Y
Y
P
Q
Site 7
Y86
F
L
E
S
L
E
L
Y
Y
P
Q
L
Y
K
K
Site 8
Y87
L
E
S
L
E
L
Y
Y
P
Q
L
Y
K
K
V
Site 9
Y91
E
L
Y
Y
P
Q
L
Y
K
K
V
T
G
K
E
Site 10
T95
P
Q
L
Y
K
K
V
T
G
K
E
P
A
R
V
Site 11
T134
Q
K
K
V
Q
D
L
T
A
L
L
S
S
K
D
Site 12
S138
Q
D
L
T
A
L
L
S
S
K
D
D
F
I
K
Site 13
S152
K
E
L
R
V
K
D
S
L
L
R
K
H
Q
E
Site 14
S193
A
M
R
L
A
H
Q
S
E
E
K
G
A
A
L
Site 15
S216
E
I
D
Q
L
K
H
S
L
M
K
A
E
D
D
Site 16
T231
C
K
V
E
R
K
H
T
L
K
L
R
H
A
M
Site 17
S243
H
A
M
E
Q
R
P
S
Q
E
L
L
W
E
L
Site 18
S267
R
V
Q
E
L
E
A
S
V
Q
E
G
K
L
D
Site 19
S276
Q
E
G
K
L
D
R
S
S
P
Y
I
Q
V
L
Site 20
S277
E
G
K
L
D
R
S
S
P
Y
I
Q
V
L
E
Site 21
T300
D
H
Q
E
Q
A
N
T
I
F
S
L
R
K
D
Site 22
S303
E
Q
A
N
T
I
F
S
L
R
K
D
L
R
Q
Site 23
S336
C
L
A
L
R
K
D
S
K
M
Y
K
D
R
I
Site 24
Y339
L
R
K
D
S
K
M
Y
K
D
R
I
E
A
I
Site 25
T420
L
R
R
Q
Q
L
E
T
L
V
L
S
S
D
L
Site 26
S431
S
S
D
L
E
D
G
S
P
R
R
S
Q
E
L
Site 27
S435
E
D
G
S
P
R
R
S
Q
E
L
S
L
P
Q
Site 28
S439
P
R
R
S
Q
E
L
S
L
P
Q
D
L
E
D
Site 29
T447
L
P
Q
D
L
E
D
T
Q
L
S
D
K
G
C
Site 30
S460
G
C
L
A
G
G
G
S
P
K
Q
P
F
A
A
Site 31
S484
P
H
D
A
G
L
S
S
G
E
P
P
E
K
E
Site 32
S498
E
R
R
R
L
K
E
S
F
E
N
Y
R
R
K
Site 33
Y502
L
K
E
S
F
E
N
Y
R
R
K
R
A
L
R
Site 34
T525
G
E
E
D
R
E
N
T
T
G
S
D
N
T
D
Site 35
S528
D
R
E
N
T
T
G
S
D
N
T
D
T
E
G
Site 36
T531
N
T
T
G
S
D
N
T
D
T
E
G
S
_
_
Site 37
T533
T
G
S
D
N
T
D
T
E
G
S
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation