KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
VPS16
Full Name:
Vacuolar protein sorting-associated protein 16 homolog
Alias:
Vacuolar protein sorting-associated 16
Type:
Mass (Da):
94694
Number AA:
839
UniProt ID:
Q9H269
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030897
GO:0005769
GO:0005770
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
D
S
A
F
Y
R
K
Y
E
L
Y
S
M
D
W
Site 2
Y23
F
Y
R
K
Y
E
L
Y
S
M
D
W
D
L
K
Site 3
S61
W
R
K
E
K
A
A
S
V
R
P
V
L
D
I
Site 4
S88
W
K
S
G
P
V
V
S
L
G
W
S
A
E
E
Site 5
Y109
E
D
G
A
V
L
V
Y
G
L
H
G
D
F
R
Site 6
S120
G
D
F
R
R
H
F
S
M
G
N
E
V
L
Q
Site 7
T154
L
T
G
A
H
R
F
T
L
S
A
N
V
G
D
Site 8
S156
G
A
H
R
F
T
L
S
A
N
V
G
D
L
K
Site 9
S175
P
E
V
P
G
L
Q
S
A
P
S
C
W
T
V
Site 10
S272
P
K
Q
M
V
W
C
S
R
P
R
S
K
E
R
Site 11
S276
V
W
C
S
R
P
R
S
K
E
R
A
V
V
V
Site 12
S307
Q
F
V
L
D
E
D
S
Y
L
V
P
E
L
D
Site 13
Y308
F
V
L
D
E
D
S
Y
L
V
P
E
L
D
G
Site 14
S320
L
D
G
V
R
I
F
S
R
S
T
H
E
F
L
Site 15
S322
G
V
R
I
F
S
R
S
T
H
E
F
L
H
E
Site 16
T323
V
R
I
F
S
R
S
T
H
E
F
L
H
E
V
Site 17
Y366
E
S
Q
K
A
D
E
Y
L
R
E
I
Q
E
L
Site 18
S398
H
Q
P
D
M
Q
K
S
L
L
R
A
A
S
F
Site 19
T441
Y
H
I
G
I
P
L
T
Y
S
Q
Y
K
Q
L
Site 20
T449
Y
S
Q
Y
K
Q
L
T
I
Q
V
L
L
D
R
Site 21
S499
K
V
Q
Q
K
D
V
S
D
E
D
V
A
R
A
Site 22
T514
I
N
Q
K
L
G
D
T
P
G
V
S
Y
S
D
Site 23
S518
L
G
D
T
P
G
V
S
Y
S
D
I
A
A
R
Site 24
S520
D
T
P
G
V
S
Y
S
D
I
A
A
R
A
Y
Site 25
Y527
S
D
I
A
A
R
A
Y
G
C
G
R
T
E
L
Site 26
Y541
L
A
I
K
L
L
E
Y
E
P
R
S
G
E
Q
Site 27
S545
L
L
E
Y
E
P
R
S
G
E
Q
V
P
L
L
Site 28
S563
K
R
S
K
L
A
L
S
K
A
I
E
S
G
D
Site 29
Y604
Q
P
M
A
L
S
L
Y
R
Q
F
C
K
H
Q
Site 30
Y620
L
E
T
L
K
D
L
Y
N
Q
D
D
N
H
Q
Site 31
S631
D
N
H
Q
E
L
G
S
F
H
I
R
A
S
Y
Site 32
S637
G
S
F
H
I
R
A
S
Y
A
A
E
E
R
I
Site 33
Y638
S
F
H
I
R
A
S
Y
A
A
E
E
R
I
E
Site 34
Y659
Q
T
A
A
D
A
F
Y
K
A
K
N
E
F
A
Site 35
S695
G
G
Q
F
L
D
L
S
L
H
D
T
V
T
T
Site 36
S747
W
E
E
L
E
K
F
S
K
S
K
K
S
P
I
Site 37
S749
E
L
E
K
F
S
K
S
K
K
S
P
I
G
Y
Site 38
S752
K
F
S
K
S
K
K
S
P
I
G
Y
L
P
F
Site 39
Y770
C
M
K
Q
H
N
K
Y
E
A
K
K
Y
A
S
Site 40
Y775
N
K
Y
E
A
K
K
Y
A
S
R
V
G
P
E
Site 41
S777
Y
E
A
K
K
Y
A
S
R
V
G
P
E
Q
K
Site 42
S811
H
R
N
E
A
E
L
S
L
V
L
S
H
C
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation