KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SYT4
Full Name:
Synaptotagmin-4
Alias:
Synaptotagmin IV
Type:
Mass (Da):
Number AA:
UniProt ID:
Q9H2B2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0016021
GO:0008021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S43
I
C
C
Q
R
K
S
S
K
S
N
K
T
P
P
Site 2
S45
C
Q
R
K
S
S
K
S
N
K
T
P
P
Y
K
Site 3
T48
K
S
S
K
S
N
K
T
P
P
Y
K
F
V
H
Site 4
Y51
K
S
N
K
T
P
P
Y
K
F
V
H
V
L
K
Site 5
Y63
V
L
K
G
V
D
I
Y
P
E
N
L
N
S
K
Site 6
S69
I
Y
P
E
N
L
N
S
K
K
K
F
G
A
D
Site 7
T108
L
N
G
N
F
P
K
T
N
L
K
P
G
S
P
Site 8
S114
K
T
N
L
K
P
G
S
P
S
D
L
E
N
A
Site 9
T122
P
S
D
L
E
N
A
T
P
K
L
F
L
E
G
Site 10
S133
F
L
E
G
E
K
E
S
V
S
P
E
S
L
K
Site 11
S135
E
G
E
K
E
S
V
S
P
E
S
L
K
S
S
Site 12
S138
K
E
S
V
S
P
E
S
L
K
S
S
T
S
L
Site 13
S141
V
S
P
E
S
L
K
S
S
T
S
L
T
S
E
Site 14
S142
S
P
E
S
L
K
S
S
T
S
L
T
S
E
E
Site 15
S144
E
S
L
K
S
S
T
S
L
T
S
E
E
K
Q
Site 16
T146
L
K
S
S
T
S
L
T
S
E
E
K
Q
E
K
Site 17
T156
E
K
Q
E
K
L
G
T
L
F
F
S
L
E
Y
Site 18
S160
K
L
G
T
L
F
F
S
L
E
Y
N
F
E
R
Site 19
S187
L
P
A
M
D
E
Q
S
M
T
S
D
P
Y
I
Site 20
T189
A
M
D
E
Q
S
M
T
S
D
P
Y
I
K
M
Site 21
Y193
Q
S
M
T
S
D
P
Y
I
K
M
T
I
L
P
Site 22
T197
S
D
P
Y
I
K
M
T
I
L
P
E
K
K
H
Site 23
T214
K
T
R
V
L
R
K
T
L
D
P
A
F
D
E
Site 24
T224
P
A
F
D
E
T
F
T
F
Y
G
I
P
Y
T
Site 25
Y226
F
D
E
T
F
T
F
Y
G
I
P
Y
T
Q
I
Site 26
S244
A
L
H
F
T
I
L
S
F
D
R
F
S
R
D
Site 27
S249
I
L
S
F
D
R
F
S
R
D
D
I
I
G
E
Site 28
S267
P
L
S
G
I
E
L
S
E
G
K
M
L
M
N
Site 29
S285
I
K
R
N
V
R
K
S
S
G
R
G
E
L
L
Site 30
S286
K
R
N
V
R
K
S
S
G
R
G
E
L
L
I
Site 31
S294
G
R
G
E
L
L
I
S
L
C
Y
Q
S
T
T
Site 32
S317
K
A
R
H
L
P
K
S
D
V
S
G
L
S
D
Site 33
S320
H
L
P
K
S
D
V
S
G
L
S
D
P
Y
V
Site 34
S323
K
S
D
V
S
G
L
S
D
P
Y
V
K
V
N
Site 35
Y326
V
S
G
L
S
D
P
Y
V
K
V
N
L
Y
H
Site 36
Y332
P
Y
V
K
V
N
L
Y
H
A
K
K
R
I
S
Site 37
S339
Y
H
A
K
K
R
I
S
K
K
K
T
H
V
K
Site 38
T343
K
R
I
S
K
K
K
T
H
V
K
K
C
T
P
Site 39
T349
K
T
H
V
K
K
C
T
P
N
A
V
F
N
E
Site 40
S379
V
E
F
L
V
L
D
S
E
R
G
S
R
N
E
Site 41
S383
V
L
D
S
E
R
G
S
R
N
E
V
I
G
Q
Site 42
Y411
H
W
K
E
I
C
D
Y
P
R
R
Q
I
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation