KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SEMA6A
Full Name:
Semaphorin-6A
Alias:
HT018; KIAA1368; SEM6A; SEMA; Sema domain, transmembrane domain (TM) and cytoplasmic domain (semaphorin) 6A; Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; Sema VIA; SEMA6A1; SEMA6A-1; Semaphorin 6A-1; Semaphorin VIA; Semaphorin-6A; SEMAQ; VIA
Type:
Adhesion, Membrane protein, integral
Mass (Da):
114369
Number AA:
1030
UniProt ID:
Q9H2E6
International Prot ID:
IPI00002211
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030424
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007411
GO:0007166
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T83
I
Y
T
V
D
I
D
T
S
H
T
E
E
I
Y
Site 2
S84
Y
T
V
D
I
D
T
S
H
T
E
E
I
Y
C
Site 3
S204
I
Y
R
S
L
G
E
S
P
T
L
R
T
V
K
Site 4
T692
Q
R
K
E
K
E
L
T
H
S
R
R
G
S
M
Site 5
S694
K
E
K
E
L
T
H
S
R
R
G
S
M
S
S
Site 6
S698
L
T
H
S
R
R
G
S
M
S
S
V
T
K
L
Site 7
S700
H
S
R
R
G
S
M
S
S
V
T
K
L
S
G
Site 8
S701
S
R
R
G
S
M
S
S
V
T
K
L
S
G
L
Site 9
T703
R
G
S
M
S
S
V
T
K
L
S
G
L
F
G
Site 10
S706
M
S
S
V
T
K
L
S
G
L
F
G
D
T
Q
Site 11
T712
L
S
G
L
F
G
D
T
Q
S
K
D
P
K
P
Site 12
S714
G
L
F
G
D
T
Q
S
K
D
P
K
P
E
A
Site 13
T724
P
K
P
E
A
I
L
T
P
L
M
H
N
G
K
Site 14
T734
M
H
N
G
K
L
A
T
P
G
N
T
A
K
M
Site 15
T753
D
Q
H
H
L
D
L
T
A
L
P
T
P
E
S
Site 16
T757
L
D
L
T
A
L
P
T
P
E
S
T
P
T
L
Site 17
S760
T
A
L
P
T
P
E
S
T
P
T
L
Q
Q
K
Site 18
T761
A
L
P
T
P
E
S
T
P
T
L
Q
Q
K
R
Site 19
T763
P
T
P
E
S
T
P
T
L
Q
Q
K
R
K
P
Site 20
S771
L
Q
Q
K
R
K
P
S
R
G
S
R
E
W
E
Site 21
S774
K
R
K
P
S
R
G
S
R
E
W
E
R
N
Q
Site 22
S796
K
D
M
P
P
M
G
S
P
V
I
P
T
D
L
Site 23
S808
T
D
L
P
L
R
A
S
P
S
H
I
P
S
V
Site 24
T821
S
V
V
V
L
P
I
T
Q
Q
G
Y
Q
H
E
Site 25
Y829
Q
Q
G
Y
Q
H
E
Y
V
D
Q
P
K
M
S
Site 26
S860
K
T
I
K
E
H
L
S
S
K
S
P
N
H
G
Site 27
S861
T
I
K
E
H
L
S
S
K
S
P
N
H
G
V
Site 28
S863
K
E
H
L
S
S
K
S
P
N
H
G
V
N
L
Site 29
S876
N
L
V
E
N
L
D
S
L
P
P
K
V
P
Q
Site 30
S887
K
V
P
Q
R
E
A
S
L
G
P
P
G
A
S
Site 31
S894
S
L
G
P
P
G
A
S
L
S
Q
T
G
L
S
Site 32
S896
G
P
P
G
A
S
L
S
Q
T
G
L
S
K
R
Site 33
T898
P
G
A
S
L
S
Q
T
G
L
S
K
R
L
E
Site 34
S901
S
L
S
Q
T
G
L
S
K
R
L
E
M
H
H
Site 35
S909
K
R
L
E
M
H
H
S
S
S
Y
G
V
D
Y
Site 36
S911
L
E
M
H
H
S
S
S
Y
G
V
D
Y
K
R
Site 37
Y916
S
S
S
Y
G
V
D
Y
K
R
S
Y
P
T
N
Site 38
Y920
G
V
D
Y
K
R
S
Y
P
T
N
S
L
T
R
Site 39
S924
K
R
S
Y
P
T
N
S
L
T
R
S
H
Q
A
Site 40
T926
S
Y
P
T
N
S
L
T
R
S
H
Q
A
T
T
Site 41
S928
P
T
N
S
L
T
R
S
H
Q
A
T
T
L
K
Site 42
T932
L
T
R
S
H
Q
A
T
T
L
K
R
N
N
T
Site 43
T939
T
T
L
K
R
N
N
T
N
S
S
N
S
S
H
Site 44
S941
L
K
R
N
N
T
N
S
S
N
S
S
H
L
S
Site 45
S942
K
R
N
N
T
N
S
S
N
S
S
H
L
S
R
Site 46
S945
N
T
N
S
S
N
S
S
H
L
S
R
N
Q
S
Site 47
S948
S
S
N
S
S
H
L
S
R
N
Q
S
F
G
R
Site 48
S952
S
H
L
S
R
N
Q
S
F
G
R
G
D
N
P
Site 49
S968
P
A
P
Q
R
V
D
S
I
Q
V
H
S
S
Q
Site 50
S973
V
D
S
I
Q
V
H
S
S
Q
P
S
G
Q
A
Site 51
S974
D
S
I
Q
V
H
S
S
Q
P
S
G
Q
A
V
Site 52
S977
Q
V
H
S
S
Q
P
S
G
Q
A
V
T
V
S
Site 53
T982
Q
P
S
G
Q
A
V
T
V
S
R
Q
P
S
L
Site 54
S984
S
G
Q
A
V
T
V
S
R
Q
P
S
L
N
A
Site 55
S988
V
T
V
S
R
Q
P
S
L
N
A
Y
N
S
L
Site 56
Y992
R
Q
P
S
L
N
A
Y
N
S
L
T
R
S
G
Site 57
S994
P
S
L
N
A
Y
N
S
L
T
R
S
G
L
K
Site 58
T996
L
N
A
Y
N
S
L
T
R
S
G
L
K
R
T
Site 59
S998
A
Y
N
S
L
T
R
S
G
L
K
R
T
P
S
Site 60
T1003
T
R
S
G
L
K
R
T
P
S
L
K
P
D
V
Site 61
S1005
S
G
L
K
R
T
P
S
L
K
P
D
V
P
P
Site 62
S1015
P
D
V
P
P
K
P
S
F
A
P
L
S
T
S
Site 63
S1020
K
P
S
F
A
P
L
S
T
S
M
K
P
N
D
Site 64
S1022
S
F
A
P
L
S
T
S
M
K
P
N
D
A
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation