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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPNS1
Full Name:
Protein spinster homolog 1
Alias:
HSpin1; LAT; Nrs; PP2030; Spin1; SPINL; Spinster 1; Spinster-like protein 1
Type:
Mass (Da):
56630
Number AA:
528
UniProt ID:
Q9H2V7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005743
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006869
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
S
D
T
A
P
F
L
S
Q
A
D
D
P
D
D
Site 2
T24
D
D
G
P
V
P
G
T
P
G
L
P
G
S
T
Site 3
S30
G
T
P
G
L
P
G
S
T
G
N
P
K
S
E
Site 4
S36
G
S
T
G
N
P
K
S
E
E
P
E
V
P
D
Site 5
T51
Q
E
G
L
Q
R
I
T
G
L
S
P
G
R
S
Site 6
S95
Q
F
F
N
I
G
D
S
S
S
G
L
I
Q
T
Site 7
Y122
F
G
Y
L
G
D
R
Y
N
R
K
Y
L
M
C
Site 8
Y126
G
D
R
Y
N
R
K
Y
L
M
C
G
G
I
A
Site 9
Y167
V
G
V
G
E
A
S
Y
S
T
I
A
P
T
L
Site 10
S189
D
Q
R
S
R
M
L
S
I
F
Y
F
A
I
P
Site 11
Y192
S
R
M
L
S
I
F
Y
F
A
I
P
V
G
S
Site 12
Y203
P
V
G
S
G
L
G
Y
I
A
G
S
K
V
K
Site 13
T223
W
H
W
A
L
R
V
T
P
G
L
G
V
V
A
Site 14
S250
R
G
A
V
E
R
H
S
D
L
P
P
L
N
P
Site 15
S259
L
P
P
L
N
P
T
S
W
W
A
D
L
R
A
Site 16
T287
F
T
A
V
A
F
V
T
G
S
L
A
L
W
A
Site 17
S301
A
P
A
F
L
L
R
S
R
V
V
L
G
E
T
Site 18
T308
S
R
V
V
L
G
E
T
P
P
C
L
P
G
D
Site 19
S316
P
P
C
L
P
G
D
S
C
S
S
S
D
S
L
Site 20
S319
L
P
G
D
S
C
S
S
S
D
S
L
I
F
G
Site 21
S320
P
G
D
S
C
S
S
S
D
S
L
I
F
G
L
Site 22
S344
V
G
L
G
V
E
I
S
R
R
L
R
H
S
N
Site 23
S350
I
S
R
R
L
R
H
S
N
P
R
A
D
P
L
Site 24
S442
P
Y
L
I
G
L
I
S
D
R
L
R
R
N
W
Site 25
S452
L
R
R
N
W
P
P
S
F
L
S
E
F
R
A
Site 26
S455
N
W
P
P
S
F
L
S
E
F
R
A
L
Q
F
Site 27
T506
L
L
H
E
A
G
S
T
D
D
R
I
V
V
P
Site 28
S518
V
V
P
Q
R
G
R
S
T
R
V
P
V
A
S
Site 29
T519
V
P
Q
R
G
R
S
T
R
V
P
V
A
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation