PhosphoNET

           
Protein Info 
   
Short Name:  MIXL1
Full Name:  Homeobox protein MIXL1
Alias:  Homeodomain protein MIX; MIX; MIXL
Type:  Transcription factor
Mass (Da):  24659
Number AA:  232
UniProt ID:  Q9H2W2
International Prot ID:  IPI00011187
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0006355  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T3_____MATAESRALQ
Site 2Y20EGAAFPAYRAPHAGG
Site 3S69PAPPPPASLGSPAPP
Site 4S72PPPASLGSPAPPKGA
Site 5S85GAAAPSASQRRKRTS
Site 6T91ASQRRKRTSFSAEQL
Site 7S92SQRRKRTSFSAEQLQ
Site 8S94RRKRTSFSAEQLQLL
Site 9T108LELVFRRTRYPDIHL
Site 10Y110LVFRRTRYPDIHLRE
Site 11T123RERLAALTLLPESRI
Site 12S141FQNRRAKSRRQSGKS
Site 13S145RAKSRRQSGKSFQPL
Site 14S148SRRQSGKSFQPLARP
Site 15T166LNHCAPGTETKCLKP
Site 16S195NGVGGGISDSSSQGQ
Site 17S197VGGGISDSSSQGQNF
Site 18S198GGGISDSSSQGQNFE
Site 19S199GGISDSSSQGQNFET
Site 20T206SQGQNFETCSPLSED
Site 21S208GQNFETCSPLSEDIG
Site 22S211FETCSPLSEDIGSKL
Site 23S216PLSEDIGSKLDSWEE
Site 24S220DIGSKLDSWEEHIFS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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