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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMP27
Full Name:
Matrix metalloproteinase-27
Alias:
Type:
Mass (Da):
59026
Number AA:
513
UniProt ID:
Q9H306
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y36
N
V
Q
L
A
Q
A
Y
L
N
Q
F
Y
S
L
Site 2
S53
E
G
N
H
L
V
Q
S
K
N
R
S
L
I
D
Site 3
S57
L
V
Q
S
K
N
R
S
L
I
D
D
K
I
R
Site 4
S80
T
V
T
G
K
L
D
S
N
T
L
E
I
M
K
Site 5
T82
T
G
K
L
D
S
N
T
L
E
I
M
K
T
P
Site 6
T88
N
T
L
E
I
M
K
T
P
R
C
G
V
P
D
Site 7
Y99
G
V
P
D
V
G
Q
Y
G
Y
T
L
P
G
W
Site 8
Y101
P
D
V
G
Q
Y
G
Y
T
L
P
G
W
R
K
Site 9
Y109
T
L
P
G
W
R
K
Y
N
L
T
Y
R
I
I
Site 10
T119
T
Y
R
I
I
N
Y
T
P
D
M
A
R
A
A
Site 11
T147
K
V
T
P
L
K
F
T
K
I
S
K
G
I
A
Site 12
Y171
V
H
G
R
C
P
R
Y
F
D
G
P
L
G
V
Site 13
S225
F
G
H
A
L
G
L
S
H
S
N
D
Q
T
A
Site 14
S227
H
A
L
G
L
S
H
S
N
D
Q
T
A
L
M
Site 15
T231
L
S
H
S
N
D
Q
T
A
L
M
F
P
N
Y
Site 16
Y238
T
A
L
M
F
P
N
Y
V
S
L
D
P
R
K
Site 17
S240
L
M
F
P
N
Y
V
S
L
D
P
R
K
Y
P
Site 18
Y246
V
S
L
D
P
R
K
Y
P
L
S
Q
D
D
I
Site 19
S249
D
P
R
K
Y
P
L
S
Q
D
D
I
N
G
I
Site 20
T289
D
L
T
F
D
A
I
T
T
F
R
R
E
V
M
Site 21
Y307
G
R
H
L
W
R
I
Y
Y
D
I
T
D
V
E
Site 22
Y308
R
H
L
W
R
I
Y
Y
D
I
T
D
V
E
F
Site 23
Y333
P
A
D
L
Q
A
A
Y
E
N
P
R
D
K
I
Site 24
Y354
N
F
W
M
I
R
G
Y
A
V
L
P
D
Y
P
Site 25
Y360
G
Y
A
V
L
P
D
Y
P
K
S
I
H
T
L
Site 26
S363
V
L
P
D
Y
P
K
S
I
H
T
L
G
F
P
Site 27
T384
D
A
A
V
C
D
K
T
T
R
K
T
Y
F
F
Site 28
Y389
D
K
T
T
R
K
T
Y
F
F
V
G
I
W
C
Site 29
T405
R
F
D
E
M
T
Q
T
M
D
K
G
F
P
Q
Site 30
Y446
R
G
S
K
Q
F
E
Y
D
I
K
T
K
N
I
Site 31
S471
Q
C
K
E
P
K
N
S
S
F
G
F
D
I
N
Site 32
S472
C
K
E
P
K
N
S
S
F
G
F
D
I
N
K
Site 33
S484
I
N
K
E
K
A
H
S
G
G
I
K
I
L
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation