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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCTD10
Full Name:
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3
Alias:
MSTP028; Potassium channel tetramerisation domain containing 10
Type:
Mass (Da):
35430
Number AA:
UniProt ID:
Q9H3F6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005249
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
E
E
M
S
G
E
S
V
V
S
S
A
V
P
Site 2
S11
M
S
G
E
S
V
V
S
S
A
V
P
A
A
A
Site 3
S12
S
G
E
S
V
V
S
S
A
V
P
A
A
A
T
Site 4
T22
P
A
A
A
T
R
T
T
S
F
K
G
T
S
P
Site 5
S23
A
A
A
T
R
T
T
S
F
K
G
T
S
P
S
Site 6
T27
R
T
T
S
F
K
G
T
S
P
S
S
K
Y
V
Site 7
S28
T
T
S
F
K
G
T
S
P
S
S
K
Y
V
K
Site 8
S30
S
F
K
G
T
S
P
S
S
K
Y
V
K
L
N
Site 9
S31
F
K
G
T
S
P
S
S
K
Y
V
K
L
N
V
Site 10
Y33
G
T
S
P
S
S
K
Y
V
K
L
N
V
G
G
Site 11
T55
Q
T
L
T
K
Q
D
T
M
L
K
A
M
F
S
Site 12
T69
S
G
R
M
E
V
L
T
D
S
E
G
W
I
L
Site 13
T86
R
C
G
K
H
F
G
T
I
L
N
Y
L
R
D
Site 14
S101
G
A
V
P
L
P
E
S
R
R
E
I
E
E
L
Site 15
T133
A
A
L
Q
N
K
D
T
Y
E
P
F
C
K
V
Site 16
Y134
A
L
Q
N
K
D
T
Y
E
P
F
C
K
V
P
Site 17
S146
K
V
P
V
I
T
S
S
K
E
E
Q
K
L
I
Site 18
Y165
K
P
A
V
K
L
L
Y
N
R
S
N
N
K
Y
Site 19
S168
V
K
L
L
Y
N
R
S
N
N
K
Y
S
Y
T
Site 20
Y172
Y
N
R
S
N
N
K
Y
S
Y
T
S
N
S
D
Site 21
S173
N
R
S
N
N
K
Y
S
Y
T
S
N
S
D
D
Site 22
Y174
R
S
N
N
K
Y
S
Y
T
S
N
S
D
D
N
Site 23
S178
K
Y
S
Y
T
S
N
S
D
D
N
M
L
K
N
Site 24
S193
I
E
L
F
D
K
L
S
L
R
F
N
G
R
V
Site 25
T240
Y
A
T
E
K
K
Q
T
K
V
E
F
P
E
A
Site 26
Y250
E
F
P
E
A
R
I
Y
E
E
T
L
N
I
L
Site 27
T253
E
A
R
I
Y
E
E
T
L
N
I
L
L
Y
E
Site 28
Y259
E
T
L
N
I
L
L
Y
E
A
Q
D
G
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation