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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NDST4
Full Name:
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
Alias:
EC 2.8.2.-; EC 2.8.2.8; EC 3.-.-.-; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
Type:
Golgi membrane, Membrane, Integral membrane, Golgi apparatus protein
Mass (Da):
100716
Number AA:
872
UniProt ID:
Q9H3R1
International Prot ID:
IPI00021733
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0015016
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T42
S
G
Y
K
Q
E
M
T
L
I
E
T
T
A
E
Site 2
T53
T
T
A
E
A
E
C
T
D
I
K
I
L
P
Y
Site 3
S62
I
K
I
L
P
Y
R
S
M
E
L
K
T
V
K
Site 4
T67
Y
R
S
M
E
L
K
T
V
K
P
I
D
T
S
Site 5
T76
K
P
I
D
T
S
K
T
D
P
T
V
L
L
F
Site 6
T79
D
T
S
K
T
D
P
T
V
L
L
F
V
E
S
Site 7
Y106
L
E
S
S
R
F
Q
Y
H
M
V
I
A
P
G
Site 8
T121
K
G
D
I
P
P
L
T
D
N
G
K
G
K
Y
Site 9
Y128
T
D
N
G
K
G
K
Y
T
L
V
I
Y
E
N
Site 10
Y139
I
Y
E
N
I
L
K
Y
V
S
M
D
S
W
N
Site 11
S144
L
K
Y
V
S
M
D
S
W
N
R
E
L
L
E
Site 12
Y153
N
R
E
L
L
E
K
Y
C
V
E
Y
S
V
S
Site 13
S171
F
H
K
A
N
E
N
S
L
P
S
T
Q
L
K
Site 14
T175
N
E
N
S
L
P
S
T
Q
L
K
G
F
P
L
Site 15
S199
D
C
F
V
N
P
Q
S
P
L
L
H
I
T
K
Site 16
T205
Q
S
P
L
L
H
I
T
K
A
P
K
V
E
K
Site 17
Y230
F
Q
Y
N
H
S
T
Y
Q
P
V
L
L
T
E
Site 18
S243
T
E
L
Q
T
E
K
S
L
S
S
L
S
S
K
Site 19
S245
L
Q
T
E
K
S
L
S
S
L
S
S
K
T
L
Site 20
S246
Q
T
E
K
S
L
S
S
L
S
S
K
T
L
F
Site 21
S248
E
K
S
L
S
S
L
S
S
K
T
L
F
A
T
Site 22
T297
F
L
S
G
K
R
L
T
L
S
L
D
R
Y
I
Site 23
T343
R
T
Q
V
A
N
F
T
F
N
L
G
F
S
G
Site 24
Y353
L
G
F
S
G
K
F
Y
H
T
G
T
E
E
E
Site 25
S393
P
H
L
F
H
N
E
S
S
L
V
E
Q
M
I
Site 26
Y417
G
I
P
I
N
M
G
Y
A
V
A
P
H
H
S
Site 27
Y427
A
P
H
H
S
G
V
Y
P
V
H
I
Q
L
Y
Site 28
Y451
Q
V
T
S
T
E
E
Y
P
H
L
K
P
A
R
Site 29
Y459
P
H
L
K
P
A
R
Y
R
K
G
F
I
H
N
Site 30
S467
R
K
G
F
I
H
N
S
I
M
V
L
P
R
Q
Site 31
Y485
L
F
T
H
T
I
F
Y
K
E
Y
P
G
G
P
Site 32
Y488
H
T
I
F
Y
K
E
Y
P
G
G
P
Q
E
L
Site 33
S498
G
P
Q
E
L
D
K
S
I
R
G
G
E
L
F
Site 34
T518
N
P
I
S
I
F
M
T
H
L
S
N
Y
G
N
Site 35
Y523
F
M
T
H
L
S
N
Y
G
N
D
R
L
G
L
Site 36
Y560
P
V
Q
L
A
H
Q
Y
F
E
L
F
P
E
Q
Site 37
T590
D
I
W
S
R
E
K
T
C
D
H
L
P
K
F
Site 38
S622
L
M
H
P
S
I
I
S
N
L
P
S
P
K
T
Site 39
S626
S
I
I
S
N
L
P
S
P
K
T
F
E
E
V
Site 40
T629
S
N
L
P
S
P
K
T
F
E
E
V
Q
F
F
Site 41
S656
M
D
F
F
P
T
P
S
N
T
T
S
D
F
L
Site 42
T658
F
F
P
T
P
S
N
T
T
S
D
F
L
F
E
Site 43
S660
P
T
P
S
N
T
T
S
D
F
L
F
E
K
S
Site 44
S667
S
D
F
L
F
E
K
S
A
N
Y
F
H
S
E
Site 45
Y670
L
F
E
K
S
A
N
Y
F
H
S
E
E
A
P
Site 46
S682
E
A
P
R
R
A
A
S
L
V
P
K
A
K
I
Site 47
S697
I
T
I
L
I
D
P
S
D
R
A
Y
S
W
Y
Site 48
Y701
I
D
P
S
D
R
A
Y
S
W
Y
Q
H
Q
R
Site 49
S702
D
P
S
D
R
A
Y
S
W
Y
Q
H
Q
R
S
Site 50
Y704
S
D
R
A
Y
S
W
Y
Q
H
Q
R
S
H
E
Site 51
T726
N
F
Y
E
V
I
S
T
G
H
W
A
P
S
D
Site 52
S732
S
T
G
H
W
A
P
S
D
L
K
T
L
Q
R
Site 53
T736
W
A
P
S
D
L
K
T
L
Q
R
R
C
L
V
Site 54
Y757
H
I
E
R
W
L
T
Y
F
A
T
S
Q
L
L
Site 55
T777
Q
L
R
S
D
P
A
T
V
M
D
E
V
Q
K
Site 56
T789
V
Q
K
F
L
G
V
T
P
R
Y
N
Y
S
E
Site 57
Y792
F
L
G
V
T
P
R
Y
N
Y
S
E
A
L
T
Site 58
Y794
G
V
T
P
R
Y
N
Y
S
E
A
L
T
F
D
Site 59
T799
Y
N
Y
S
E
A
L
T
F
D
P
Q
K
G
F
Site 60
T816
Q
L
L
E
G
G
K
T
K
C
L
G
K
S
K
Site 61
S822
K
T
K
C
L
G
K
S
K
G
R
K
Y
P
P
Site 62
Y827
G
K
S
K
G
R
K
Y
P
P
M
D
P
E
S
Site 63
S834
Y
P
P
M
D
P
E
S
R
T
F
L
S
N
Y
Site 64
T836
P
M
D
P
E
S
R
T
F
L
S
N
Y
Y
R
Site 65
S839
P
E
S
R
T
F
L
S
N
Y
Y
R
D
H
N
Site 66
Y841
S
R
T
F
L
S
N
Y
Y
R
D
H
N
V
E
Site 67
S862
R
L
G
Q
P
L
P
S
W
L
R
Q
E
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation