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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SRMS
Full Name:
Tyrosine-protein kinase Srms
Alias:
Type:
Mass (Da):
54507
Number AA:
488
UniProt ID:
Q9H3Y6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
G
G
E
P
D
H
G
T
P
G
S
L
D
P
N
Site 2
S33
P
D
H
G
T
P
G
S
L
D
P
N
T
D
P
Site 3
T38
P
G
S
L
D
P
N
T
D
P
V
P
T
L
P
Site 4
T43
P
N
T
D
P
V
P
T
L
P
A
E
P
C
S
Site 5
S71
A
R
C
G
G
E
L
S
V
R
R
G
D
R
L
Site 6
Y87
A
L
E
E
G
G
G
Y
I
F
A
R
R
L
S
Site 7
S94
Y
I
F
A
R
R
L
S
G
Q
P
S
A
G
L
Site 8
S98
R
R
L
S
G
Q
P
S
A
G
L
V
P
I
T
Site 9
S111
I
T
H
V
A
K
A
S
P
E
T
L
S
D
Q
Site 10
T114
V
A
K
A
S
P
E
T
L
S
D
Q
P
W
Y
Site 11
S116
K
A
S
P
E
T
L
S
D
Q
P
W
Y
F
S
Site 12
Y121
T
L
S
D
Q
P
W
Y
F
S
G
V
S
R
T
Site 13
S136
Q
A
Q
Q
L
L
L
S
P
P
N
E
P
G
A
Site 14
S149
G
A
F
L
I
R
P
S
E
S
S
L
G
G
Y
Site 15
S152
L
I
R
P
S
E
S
S
L
G
G
Y
S
L
S
Site 16
S157
E
S
S
L
G
G
Y
S
L
S
V
R
A
Q
A
Site 17
S172
K
V
C
H
Y
R
V
S
M
A
A
D
G
S
L
Site 18
S178
V
S
M
A
A
D
G
S
L
Y
L
Q
K
G
R
Site 19
T195
P
G
L
E
E
L
L
T
Y
Y
K
A
N
W
K
Site 20
Y196
G
L
E
E
L
L
T
Y
Y
K
A
N
W
K
L
Site 21
Y197
L
E
E
L
L
T
Y
Y
K
A
N
W
K
L
I
Site 22
S228
D
V
W
E
R
P
H
S
E
F
A
L
G
R
K
Site 23
Y240
G
R
K
L
G
E
G
Y
F
G
E
V
W
E
G
Site 24
T316
N
L
Q
A
F
L
G
T
P
E
G
R
A
L
R
Site 25
Y340
Q
V
A
E
G
M
S
Y
L
E
E
Q
R
V
V
Site 26
Y380
R
L
L
K
D
D
I
Y
S
P
S
S
S
S
K
Site 27
S381
L
L
K
D
D
I
Y
S
P
S
S
S
S
K
I
Site 28
S383
K
D
D
I
Y
S
P
S
S
S
S
K
I
P
V
Site 29
S384
D
D
I
Y
S
P
S
S
S
S
K
I
P
V
K
Site 30
S385
D
I
Y
S
P
S
S
S
S
K
I
P
V
K
W
Site 31
S386
I
Y
S
P
S
S
S
S
K
I
P
V
K
W
T
Site 32
Y400
T
A
P
E
A
A
N
Y
R
V
F
S
Q
K
S
Site 33
S404
A
A
N
Y
R
V
F
S
Q
K
S
D
V
W
S
Site 34
S407
Y
R
V
F
S
Q
K
S
D
V
W
S
F
G
V
Site 35
S411
S
Q
K
S
D
V
W
S
F
G
V
L
L
H
E
Site 36
Y422
L
L
H
E
V
F
T
Y
G
Q
C
P
Y
E
G
Site 37
Y427
F
T
Y
G
Q
C
P
Y
E
G
M
T
N
H
E
Site 38
Y443
L
Q
Q
I
M
R
G
Y
R
L
P
R
P
A
A
Site 39
S465
L
M
L
E
C
W
R
S
S
P
E
E
R
P
S
Site 40
S466
M
L
E
C
W
R
S
S
P
E
E
R
P
S
F
Site 41
S472
S
S
P
E
E
R
P
S
F
A
T
L
R
E
K
Site 42
T475
E
E
R
P
S
F
A
T
L
R
E
K
L
H
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation