PhosphoNET

           
Protein Info 
   
Short Name:  LIME1
Full Name:  Lck-interacting transmembrane adapter 1
Alias:  Lck-interacting molecule; LP8067
Type:  Adapter/scaffold protein
Mass (Da):  31288
Number AA:  295
UniProt ID:  Q9H400
International Prot ID:  IPI00646802
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0005886   Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0006955     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T29LSLWALCTACRRPED
Site 2S61SATAAEASLLRRTHL
Site 3T66EASLLRRTHLCSLSK
Site 4S70LRRTHLCSLSKSDTR
Site 5S72RTHLCSLSKSDTRLH
Site 6S74HLCSLSKSDTRLHEL
Site 7T76CSLSKSDTRLHELHR
Site 8S87ELHRGPRSSRALRPA
Site 9S88LHRGPRSSRALRPAS
Site 10S95SRALRPASMDLLRPH
Site 11T111LEVSRDITGPQAAPS
Site 12S118TGPQAAPSAFPHQEL
Site 13Y145CAGLEATYSNVGLAA
Site 14Y167ASPVVAEYARVQKRK
Site 15T176RVQKRKGTHRSPQEP
Site 16S179KRKGTHRSPQEPQQG
Site 17T191QQGKTEVTPAAQVDV
Site 18Y200AAQVDVLYSRVCKPK
Site 19S201AQVDVLYSRVCKPKR
Site 20T214KRRDPGPTTDPLDPK
Site 21T215RRDPGPTTDPLDPKG
Site 22Y235ALAGDLAYQTLPLRA
Site 23S247LRALDVDSGPLENVY
Site 24Y254SGPLENVYESIRELG
Site 25S256PLENVYESIRELGDP
Site 26S267LGDPAGRSSTCGAGT
Site 27S268GDPAGRSSTCGAGTP
Site 28T269DPAGRSSTCGAGTPP
Site 29T274SSTCGAGTPPASSCP
Site 30S278GAGTPPASSCPSLGR
Site 31S279AGTPPASSCPSLGRG
Site 32S282PPASSCPSLGRGWRP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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