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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DSN1
Full Name:
Kinetochore-associated protein DSN1 homolog
Alias:
C20orf172; Chromosome 20 open reading frame 172; CT172; DJ469A13.2; DSN1, MIND kinetochore complex component,; FLJ13346; Kinetochore null 3; KNL3; MGC32987; MIS13
Type:
Mass (Da):
40067
Number AA:
356
UniProt ID:
Q9H410
International Prot ID:
IPI00016580
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000444
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007059
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
S
V
T
R
S
E
I
Site 2
T5
_
_
_
M
T
S
V
T
R
S
E
I
I
D
E
Site 3
S7
_
M
T
S
V
T
R
S
E
I
I
D
E
K
G
Site 4
T20
K
G
P
V
M
S
K
T
H
D
H
Q
L
E
S
Site 5
S27
T
H
D
H
Q
L
E
S
S
L
S
P
V
E
V
Site 6
S28
H
D
H
Q
L
E
S
S
L
S
P
V
E
V
F
Site 7
S30
H
Q
L
E
S
S
L
S
P
V
E
V
F
A
K
Site 8
T38
P
V
E
V
F
A
K
T
S
A
S
L
E
M
N
Site 9
S41
V
F
A
K
T
S
A
S
L
E
M
N
Q
G
V
Site 10
S49
L
E
M
N
Q
G
V
S
E
E
R
I
H
L
G
Site 11
S57
E
E
R
I
H
L
G
S
S
P
K
K
G
G
N
Site 12
S58
E
R
I
H
L
G
S
S
P
K
K
G
G
N
C
Site 13
S68
K
G
G
N
C
D
L
S
H
Q
E
R
L
Q
S
Site 14
S75
S
H
Q
E
R
L
Q
S
K
S
L
H
L
S
P
Site 15
S77
Q
E
R
L
Q
S
K
S
L
H
L
S
P
Q
E
Site 16
S81
Q
S
K
S
L
H
L
S
P
Q
E
Q
S
A
S
Site 17
S86
H
L
S
P
Q
E
Q
S
A
S
Y
Q
D
R
R
Site 18
S88
S
P
Q
E
Q
S
A
S
Y
Q
D
R
R
Q
S
Site 19
Y89
P
Q
E
Q
S
A
S
Y
Q
D
R
R
Q
S
W
Site 20
S95
S
Y
Q
D
R
R
Q
S
W
R
R
A
S
M
K
Site 21
S100
R
Q
S
W
R
R
A
S
M
K
E
T
N
R
R
Site 22
T104
R
R
A
S
M
K
E
T
N
R
R
K
S
L
H
Site 23
S109
K
E
T
N
R
R
K
S
L
H
P
I
H
Q
G
Site 24
T118
H
P
I
H
Q
G
I
T
E
L
S
R
S
I
S
Site 25
S121
H
Q
G
I
T
E
L
S
R
S
I
S
V
D
L
Site 26
S123
G
I
T
E
L
S
R
S
I
S
V
D
L
A
E
Site 27
S125
T
E
L
S
R
S
I
S
V
D
L
A
E
S
K
Site 28
S131
I
S
V
D
L
A
E
S
K
R
L
G
C
L
L
Site 29
T156
L
E
P
F
L
R
D
T
K
G
F
S
L
E
S
Site 30
S160
L
R
D
T
K
G
F
S
L
E
S
F
R
A
K
Site 31
S163
T
K
G
F
S
L
E
S
F
R
A
K
A
S
S
Site 32
S170
S
F
R
A
K
A
S
S
L
S
E
E
L
K
H
Site 33
S172
R
A
K
A
S
S
L
S
E
E
L
K
H
F
A
Site 34
T187
D
G
L
E
T
D
G
T
L
Q
K
C
F
E
D
Site 35
S200
E
D
S
N
G
K
A
S
D
F
S
L
E
A
S
Site 36
S203
N
G
K
A
S
D
F
S
L
E
A
S
V
A
E
Site 37
S207
S
D
F
S
L
E
A
S
V
A
E
M
K
E
Y
Site 38
Y214
S
V
A
E
M
K
E
Y
I
T
K
F
S
L
E
Site 39
S219
K
E
Y
I
T
K
F
S
L
E
R
Q
T
W
D
Site 40
T224
K
F
S
L
E
R
Q
T
W
D
Q
L
L
L
H
Site 41
S244
K
E
I
L
S
R
G
S
T
E
A
K
I
T
E
Site 42
T245
E
I
L
S
R
G
S
T
E
A
K
I
T
E
V
Site 43
T250
G
S
T
E
A
K
I
T
E
V
K
V
E
P
M
Site 44
T258
E
V
K
V
E
P
M
T
Y
L
G
S
S
Q
N
Site 45
Y259
V
K
V
E
P
M
T
Y
L
G
S
S
Q
N
E
Site 46
S263
P
M
T
Y
L
G
S
S
Q
N
E
V
L
N
T
Site 47
T270
S
Q
N
E
V
L
N
T
K
P
D
Y
Q
K
I
Site 48
Y274
V
L
N
T
K
P
D
Y
Q
K
I
L
Q
N
Q
Site 49
S298
V
M
D
E
L
Q
G
S
V
K
Q
L
Q
A
F
Site 50
T310
Q
A
F
M
D
E
S
T
Q
C
F
Q
K
V
S
Site 51
S331
S
M
Q
Q
L
D
P
S
P
A
R
K
L
L
K
Site 52
S350
N
P
P
A
I
H
G
S
G
S
G
S
C
Q
_
Site 53
S352
P
A
I
H
G
S
G
S
G
S
C
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation