PhosphoNET

           
Protein Info 
   
Short Name:  POFUT1
Full Name:  GDP-fucose protein O-fucosyltransferase 1
Alias:  EC 2.4.1.221; GDP-fucose protein O-fucosyltransferase 1; KIAA0180; O-FucT-1; OFUT1
Type:  Transferase
Mass (Da):  43956
Number AA:  388
UniProt ID:  Q9H488
International Prot ID:  IPI00058192
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0016020   Uniprot OncoNet
Molecular Function:  GO:0030145  GO:0046922   PhosphoSite+ KinaseNET
Biological Process:  GO:0007219  GO:0016266  GO:0006004 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S28LPGMPAGSWDPAGYL
Site 2T81QHHKPPFTNLHVSYQ
Site 3Y87FTNLHVSYQKYFKLE
Site 4Y90LHVSYQKYFKLEPLQ
Site 5Y99KLEPLQAYHRVISLE
Site 6S104QAYHRVISLEDFMEK
Site 7Y125PPEKRVAYCFEVAAQ
Site 8S134FEVAAQRSPDKKTCP
Site 9T139QRSPDKKTCPMKEGN
Site 10T166FNKSELFTGISFSAS
Site 11S169SELFTGISFSASYRE
Site 12S171LFTGISFSASYREQW
Site 13S173TGISFSASYREQWSQ
Site 14S179ASYREQWSQRFSPKE
Site 15S183EQWSQRFSPKEHPVL
Site 16Y211EHRPLQKYMVWSDEM
Site 17T221WSDEMVKTGEAQIHA
Site 18S259LKDGTAGSHFMASPQ
Site 19S264AGSHFMASPQCVGYS
Site 20S273QCVGYSRSTAAPLTM
Site 21S305VRSLDAQSVYVATDS
Site 22Y307SLDAQSVYVATDSES
Site 23S312SVYVATDSESYVPEL
Site 24S314YVATDSESYVPELQQ
Site 25Y315VATDSESYVPELQQL
Site 26S331KGKVKVVSLKPEVAQ
Site 27S373RDLQGRPSSFFGMDR
Site 28S374DLQGRPSSFFGMDRP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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