KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DPEP2
Full Name:
Dipeptidase 2
Alias:
Type:
Mass (Da):
53306
Number AA:
486
UniProt ID:
Q9H4A9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
S
G
L
E
G
P
G
T
F
G
R
W
P
L
L
Site 2
Y34
L
Q
P
V
T
C
A
Y
T
T
P
G
P
P
R
Site 3
T36
P
V
T
C
A
Y
T
T
P
G
P
P
R
A
L
Site 4
T44
P
G
P
P
R
A
L
T
T
L
G
A
P
R
A
Site 5
T53
L
G
A
P
R
A
H
T
M
P
G
T
Y
A
P
Site 6
T57
R
A
H
T
M
P
G
T
Y
A
P
S
T
T
L
Site 7
S61
M
P
G
T
Y
A
P
S
T
T
L
S
S
P
S
Site 8
T62
P
G
T
Y
A
P
S
T
T
L
S
S
P
S
T
Site 9
T63
G
T
Y
A
P
S
T
T
L
S
S
P
S
T
Q
Site 10
S65
Y
A
P
S
T
T
L
S
S
P
S
T
Q
G
L
Site 11
S66
A
P
S
T
T
L
S
S
P
S
T
Q
G
L
Q
Site 12
S68
S
T
T
L
S
S
P
S
T
Q
G
L
Q
E
Q
Site 13
T69
T
T
L
S
S
P
S
T
Q
G
L
Q
E
Q
A
Site 14
Y100
P
L
V
L
R
Q
V
Y
Q
K
G
L
Q
D
V
Site 15
S113
D
V
N
L
R
N
F
S
Y
G
Q
T
S
L
D
Site 16
Y114
V
N
L
R
N
F
S
Y
G
Q
T
S
L
D
R
Site 17
T117
R
N
F
S
Y
G
Q
T
S
L
D
R
L
R
D
Site 18
S118
N
F
S
Y
G
Q
T
S
L
D
R
L
R
D
G
Site 19
Y135
G
A
Q
F
W
S
A
Y
V
P
C
Q
T
Q
D
Site 20
T149
D
R
D
A
L
R
L
T
L
E
Q
I
D
L
I
Site 21
S164
R
R
M
C
A
S
Y
S
E
L
E
L
V
T
S
Site 22
S171
S
E
L
E
L
V
T
S
A
K
A
L
N
D
T
Site 23
S196
G
G
H
S
L
D
N
S
L
S
I
L
R
T
F
Site 24
S198
H
S
L
D
N
S
L
S
I
L
R
T
F
Y
M
Site 25
T214
G
V
R
Y
L
T
L
T
H
T
C
N
T
P
W
Site 26
T216
R
Y
L
T
L
T
H
T
C
N
T
P
W
A
E
Site 27
T219
T
L
T
H
T
C
N
T
P
W
A
E
S
S
A
Site 28
S225
N
T
P
W
A
E
S
S
A
K
G
V
H
S
F
Site 29
S231
S
S
A
K
G
V
H
S
F
Y
N
N
I
S
G
Site 30
Y233
A
K
G
V
H
S
F
Y
N
N
I
S
G
L
T
Site 31
S291
A
A
R
G
V
C
N
S
A
R
N
V
P
D
D
Site 32
S328
C
N
P
S
A
N
V
S
T
V
A
D
H
F
D
Site 33
S366
P
Q
G
L
E
D
V
S
T
Y
P
V
L
I
E
Site 34
T367
Q
G
L
E
D
V
S
T
Y
P
V
L
I
E
E
Site 35
S377
V
L
I
E
E
L
L
S
R
G
W
S
E
E
E
Site 36
S381
E
L
L
S
R
G
W
S
E
E
E
L
Q
G
V
Site 37
S411
Q
E
E
N
K
W
Q
S
P
L
E
D
K
F
P
Site 38
S423
K
F
P
D
E
Q
L
S
S
S
C
H
S
D
L
Site 39
S424
F
P
D
E
Q
L
S
S
S
C
H
S
D
L
S
Site 40
S425
P
D
E
Q
L
S
S
S
C
H
S
D
L
S
R
Site 41
S428
Q
L
S
S
S
C
H
S
D
L
S
R
L
R
Q
Site 42
S431
S
S
C
H
S
D
L
S
R
L
R
Q
R
Q
S
Site 43
S438
S
R
L
R
Q
R
Q
S
L
T
S
G
Q
E
L
Site 44
S441
R
Q
R
Q
S
L
T
S
G
Q
E
L
T
E
I
Site 45
T446
L
T
S
G
Q
E
L
T
E
I
P
I
H
W
T
Site 46
S461
A
K
L
P
A
K
W
S
V
S
E
S
S
P
H
Site 47
S463
L
P
A
K
W
S
V
S
E
S
S
P
H
M
A
Site 48
S465
A
K
W
S
V
S
E
S
S
P
H
M
A
P
V
Site 49
S466
K
W
S
V
S
E
S
S
P
H
M
A
P
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation