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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TUBB1
Full Name:
Tubulin beta-1 chain
Alias:
Type:
Mass (Da):
50327
Number AA:
451
UniProt ID:
Q9H4B7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S35
H
G
I
D
L
A
G
S
D
R
G
A
S
A
L
Site 2
S40
A
G
S
D
R
G
A
S
A
L
Q
L
E
R
I
Site 3
S48
A
L
Q
L
E
R
I
S
V
Y
Y
N
E
A
Y
Site 4
Y50
Q
L
E
R
I
S
V
Y
Y
N
E
A
Y
G
R
Site 5
Y51
L
E
R
I
S
V
Y
Y
N
E
A
Y
G
R
K
Site 6
Y55
S
V
Y
Y
N
E
A
Y
G
R
K
Y
V
P
R
Site 7
Y59
N
E
A
Y
G
R
K
Y
V
P
R
A
V
L
V
Site 8
T72
L
V
D
L
E
P
G
T
M
D
S
I
R
S
S
Site 9
S75
L
E
P
G
T
M
D
S
I
R
S
S
K
L
G
Site 10
S79
T
M
D
S
I
R
S
S
K
L
G
A
L
F
Q
Site 11
S89
G
A
L
F
Q
P
D
S
F
V
H
G
N
S
G
Site 12
S124
L
E
V
V
R
H
E
S
E
S
C
D
C
L
Q
Site 13
S126
V
V
R
H
E
S
E
S
C
D
C
L
Q
G
F
Site 14
S138
Q
G
F
Q
I
V
H
S
L
G
G
G
T
G
S
Site 15
T149
G
T
G
S
G
M
G
T
L
L
M
N
K
I
R
Site 16
Y159
M
N
K
I
R
E
E
Y
P
D
R
I
M
N
S
Site 17
S166
Y
P
D
R
I
M
N
S
F
S
V
M
P
S
P
Site 18
S168
D
R
I
M
N
S
F
S
V
M
P
S
P
K
V
Site 19
S172
N
S
F
S
V
M
P
S
P
K
V
S
D
T
V
Site 20
S176
V
M
P
S
P
K
V
S
D
T
V
V
E
P
Y
Site 21
T178
P
S
P
K
V
S
D
T
V
V
E
P
Y
N
A
Site 22
Y208
C
I
D
N
E
A
L
Y
D
I
C
F
R
T
L
Site 23
T218
C
F
R
T
L
K
L
T
T
P
T
Y
G
D
L
Site 24
T219
F
R
T
L
K
L
T
T
P
T
Y
G
D
L
N
Site 25
Y222
L
K
L
T
T
P
T
Y
G
D
L
N
H
L
V
Site 26
T274
M
P
G
F
A
P
L
T
A
Q
G
S
Q
Q
Y
Site 27
S278
A
P
L
T
A
Q
G
S
Q
Q
Y
R
A
L
S
Site 28
S285
S
Q
Q
Y
R
A
L
S
V
A
E
L
T
Q
Q
Site 29
T323
I
F
R
G
K
M
S
T
K
E
V
D
Q
Q
L
Site 30
S332
E
V
D
Q
Q
L
L
S
V
Q
T
R
N
S
S
Site 31
S339
S
V
Q
T
R
N
S
S
C
F
V
E
W
I
P
Site 32
S386
N
R
V
S
E
H
F
S
A
M
F
K
R
K
A
Site 33
Y398
R
K
A
F
V
H
W
Y
T
S
E
G
M
D
I
Site 34
T439
L
E
E
D
E
E
V
T
E
E
A
E
M
E
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation