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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NXF3
Full Name:
Nuclear RNA export factor 3
Alias:
Nuclear RNA export factor 2; TAP like 2; TAPL2; TAPL-2
Type:
Intracellular, Nuclear RNA export factor complex, Cytoplasm, Nucleus protein
Mass (Da):
60102
Number AA:
531
UniProt ID:
Q9H4D5
International Prot ID:
IPI00004930
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0042272
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
S
L
P
S
G
H
T
T
G
H
T
D
Q
V
V
Site 2
T12
S
G
H
T
T
G
H
T
D
Q
V
V
Q
R
R
Site 3
Y26
R
A
R
C
W
D
I
Y
Q
R
R
F
S
S
R
Site 4
S31
D
I
Y
Q
R
R
F
S
S
R
S
E
P
V
N
Site 5
S32
I
Y
Q
R
R
F
S
S
R
S
E
P
V
N
P
Site 6
S34
Q
R
R
F
S
S
R
S
E
P
V
N
P
G
M
Site 7
S43
P
V
N
P
G
M
H
S
S
S
H
Q
Q
Q
D
Site 8
S44
V
N
P
G
M
H
S
S
S
H
Q
Q
Q
D
G
Site 9
S45
N
P
G
M
H
S
S
S
H
Q
Q
Q
D
G
D
Site 10
Y66
H
M
D
S
P
V
R
Y
T
P
Y
T
I
S
P
Site 11
T67
M
D
S
P
V
R
Y
T
P
Y
T
I
S
P
Y
Site 12
Y69
S
P
V
R
Y
T
P
Y
T
I
S
P
Y
N
R
Site 13
T70
P
V
R
Y
T
P
Y
T
I
S
P
Y
N
R
K
Site 14
S72
R
Y
T
P
Y
T
I
S
P
Y
N
R
K
G
S
Site 15
Y74
T
P
Y
T
I
S
P
Y
N
R
K
G
S
F
R
Site 16
S79
S
P
Y
N
R
K
G
S
F
R
K
Q
D
Q
T
Site 17
T86
S
F
R
K
Q
D
Q
T
H
V
N
M
E
R
E
Site 18
T109
E
G
N
M
P
D
G
T
L
G
S
W
F
K
I
Site 19
Y124
T
V
P
F
G
I
K
Y
N
E
K
W
L
L
N
Site 20
Y148
F
V
P
V
E
F
H
Y
E
N
M
H
A
S
F
Site 21
S200
F
V
H
R
E
L
K
S
E
K
V
E
Q
I
K
Site 22
Y229
D
I
Q
R
L
P
F
Y
P
D
M
V
N
R
D
Site 23
T237
P
D
M
V
N
R
D
T
K
M
A
S
N
P
R
Site 24
S241
N
R
D
T
K
M
A
S
N
P
R
K
C
M
A
Site 25
T260
V
H
E
E
N
I
P
T
V
M
S
A
G
E
M
Site 26
S283
G
E
K
C
A
D
R
S
P
V
C
T
T
F
S
Site 27
T287
A
D
R
S
P
V
C
T
T
F
S
D
T
S
S
Site 28
T288
D
R
S
P
V
C
T
T
F
S
D
T
S
S
N
Site 29
S290
S
P
V
C
T
T
F
S
D
T
S
S
N
I
N
Site 30
T292
V
C
T
T
F
S
D
T
S
S
N
I
N
S
I
Site 31
S294
T
T
F
S
D
T
S
S
N
I
N
S
I
L
E
Site 32
S298
D
T
S
S
N
I
N
S
I
L
E
L
F
P
K
Site 33
S314
L
C
L
D
G
Q
Q
S
P
R
A
T
L
C
G
Site 34
T318
G
Q
Q
S
P
R
A
T
L
C
G
T
E
A
H
Site 35
T330
E
A
H
K
R
L
P
T
C
K
G
S
F
F
G
Site 36
S334
R
L
P
T
C
K
G
S
F
F
G
S
E
M
L
Site 37
Y353
L
Q
F
L
Q
Q
Y
Y
L
I
Y
D
S
G
D
Site 38
Y356
L
Q
Q
Y
Y
L
I
Y
D
S
G
D
R
Q
G
Site 39
S366
G
D
R
Q
G
L
L
S
A
Y
H
D
E
A
C
Site 40
Y368
R
Q
G
L
L
S
A
Y
H
D
E
A
C
F
S
Site 41
S377
D
E
A
C
F
S
L
S
I
P
F
N
P
E
D
Site 42
S385
I
P
F
N
P
E
D
S
A
P
S
S
F
C
K
Site 43
S389
P
E
D
S
A
P
S
S
F
C
K
F
F
K
D
Site 44
Y407
I
K
I
L
K
D
P
Y
L
R
G
E
L
L
K
Site 45
S425
L
D
I
V
D
S
L
S
A
L
P
K
T
Q
H
Site 46
T430
S
L
S
A
L
P
K
T
Q
H
D
L
S
S
F
Site 47
S464
F
K
E
V
E
G
Q
S
Q
G
S
V
L
A
F
Site 48
S484
A
T
P
G
S
S
S
S
L
C
I
V
N
D
K
Site 49
T497
D
K
L
F
V
R
D
T
S
H
Q
G
T
Q
S
Site 50
S498
K
L
F
V
R
D
T
S
H
Q
G
T
Q
S
A
Site 51
T502
R
D
T
S
H
Q
G
T
Q
S
A
L
F
T
L
Site 52
S517
V
P
T
A
F
S
S
S
V
P
A
F
S
Q
E
Site 53
S522
S
S
S
V
P
A
F
S
Q
E
Q
Q
K
M
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation