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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EPB41L1
Full Name:
Band 4.1-like protein 1
Alias:
4.1N; E41L1; E4L1; Erythrocyte membrane protein band 4.1-like 1; KIAA0338; Neuronal protein 4.1
Type:
Adapter/scaffold protein
Mass (Da):
98503
Number AA:
881
UniProt ID:
Q9H4G0
International Prot ID:
IPI00024062
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005198
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006996
GO:0007010
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
T
E
T
G
P
D
S
E
V
K
K
A
Q
E
Site 2
T33
A
A
V
T
T
P
V
T
P
A
G
H
G
H
P
Site 3
S44
H
G
H
P
E
A
N
S
N
E
K
H
P
S
Q
Site 4
S50
N
S
N
E
K
H
P
S
Q
Q
D
T
R
P
A
Site 5
T54
K
H
P
S
Q
Q
D
T
R
P
A
E
Q
S
L
Site 6
S60
D
T
R
P
A
E
Q
S
L
D
M
E
E
K
D
Site 7
Y68
L
D
M
E
E
K
D
Y
S
E
A
D
G
L
S
Site 8
S69
D
M
E
E
K
D
Y
S
E
A
D
G
L
S
E
Site 9
S75
Y
S
E
A
D
G
L
S
E
R
T
T
P
S
K
Site 10
T78
A
D
G
L
S
E
R
T
T
P
S
K
A
Q
K
Site 11
T79
D
G
L
S
E
R
T
T
P
S
K
A
Q
K
S
Site 12
S81
L
S
E
R
T
T
P
S
K
A
Q
K
S
P
Q
Site 13
S86
T
P
S
K
A
Q
K
S
P
Q
K
I
A
K
K
Site 14
Y94
P
Q
K
I
A
K
K
Y
K
S
A
I
C
R
V
Site 15
S96
K
I
A
K
K
Y
K
S
A
I
C
R
V
T
L
Site 16
T102
K
S
A
I
C
R
V
T
L
L
D
A
S
E
Y
Site 17
S107
R
V
T
L
L
D
A
S
E
Y
E
C
E
V
E
Site 18
Y109
T
L
L
D
A
S
E
Y
E
C
E
V
E
K
H
Site 19
T141
E
K
D
Y
F
G
L
T
F
C
D
A
D
S
Q
Site 20
S155
Q
K
N
W
L
D
P
S
K
E
I
K
K
Q
I
Site 21
S165
I
K
K
Q
I
R
S
S
P
W
N
F
A
F
T
Site 22
T184
P
P
D
P
A
Q
L
T
E
D
I
T
R
Y
Y
Site 23
Y190
L
T
E
D
I
T
R
Y
Y
L
C
L
Q
L
R
Site 24
Y191
T
E
D
I
T
R
Y
Y
L
C
L
Q
L
R
A
Site 25
T202
Q
L
R
A
D
I
I
T
G
R
L
P
C
S
F
Site 26
Y227
V
Q
A
E
L
G
D
Y
D
A
E
E
H
V
G
Site 27
Y236
A
E
E
H
V
G
N
Y
V
S
E
L
R
F
A
Site 28
S238
E
H
V
G
N
Y
V
S
E
L
R
F
A
P
N
Site 29
T260
R
I
M
E
L
H
K
T
Y
R
G
M
T
P
G
Site 30
Y261
I
M
E
L
H
K
T
Y
R
G
M
T
P
G
E
Site 31
T265
H
K
T
Y
R
G
M
T
P
G
E
A
E
I
H
Site 32
Y283
N
A
K
K
L
S
M
Y
G
V
D
L
H
H
A
Site 33
Y329
P
K
I
L
K
I
S
Y
K
R
S
N
F
Y
I
Site 34
S332
L
K
I
S
Y
K
R
S
N
F
Y
I
K
I
R
Site 35
Y335
S
Y
K
R
S
N
F
Y
I
K
I
R
P
G
E
Site 36
Y343
I
K
I
R
P
G
E
Y
E
Q
F
E
S
T
I
Site 37
S348
G
E
Y
E
Q
F
E
S
T
I
G
F
K
L
P
Site 38
T349
E
Y
E
Q
F
E
S
T
I
G
F
K
L
P
N
Site 39
S359
F
K
L
P
N
H
R
S
A
K
R
L
W
K
V
Site 40
S391
K
G
F
L
V
M
G
S
K
F
R
Y
S
G
R
Site 41
Y395
V
M
G
S
K
F
R
Y
S
G
R
T
Q
A
Q
Site 42
S396
M
G
S
K
F
R
Y
S
G
R
T
Q
A
Q
T
Site 43
T399
K
F
R
Y
S
G
R
T
Q
A
Q
T
R
Q
A
Site 44
T403
S
G
R
T
Q
A
Q
T
R
Q
A
S
A
L
I
Site 45
S407
Q
A
Q
T
R
Q
A
S
A
L
I
D
R
P
A
Site 46
S420
P
A
P
F
F
E
R
S
S
S
K
R
Y
T
M
Site 47
S421
A
P
F
F
E
R
S
S
S
K
R
Y
T
M
S
Site 48
S422
P
F
F
E
R
S
S
S
K
R
Y
T
M
S
R
Site 49
Y425
E
R
S
S
S
K
R
Y
T
M
S
R
S
L
D
Site 50
T426
R
S
S
S
K
R
Y
T
M
S
R
S
L
D
G
Site 51
S428
S
S
K
R
Y
T
M
S
R
S
L
D
G
A
E
Site 52
S430
K
R
Y
T
M
S
R
S
L
D
G
A
E
F
S
Site 53
S437
S
L
D
G
A
E
F
S
R
P
A
S
V
S
E
Site 54
S441
A
E
F
S
R
P
A
S
V
S
E
N
H
D
A
Site 55
S443
F
S
R
P
A
S
V
S
E
N
H
D
A
G
P
Site 56
S461
K
R
D
E
D
G
E
S
G
G
Q
R
S
E
A
Site 57
S466
G
E
S
G
G
Q
R
S
E
A
E
E
G
E
V
Site 58
T475
A
E
E
G
E
V
R
T
P
T
K
I
K
E
L
Site 59
T477
E
G
E
V
R
T
P
T
K
I
K
E
L
K
P
Site 60
T489
L
K
P
E
Q
E
T
T
P
R
H
K
Q
E
F
Site 61
S510
V
L
L
K
H
Q
A
S
I
N
E
L
K
R
T
Site 62
T517
S
I
N
E
L
K
R
T
L
K
E
P
N
S
K
Site 63
S523
R
T
L
K
E
P
N
S
K
L
I
H
R
D
R
Site 64
S540
E
R
E
R
R
L
P
S
S
P
A
S
P
S
P
Site 65
S541
R
E
R
R
L
P
S
S
P
A
S
P
S
P
K
Site 66
S544
R
L
P
S
S
P
A
S
P
S
P
K
G
T
P
Site 67
S546
P
S
S
P
A
S
P
S
P
K
G
T
P
E
K
Site 68
T550
A
S
P
S
P
K
G
T
P
E
K
A
N
E
R
Site 69
S564
R
A
G
L
R
E
G
S
E
E
K
V
K
P
P
Site 70
S578
P
R
P
R
A
P
E
S
D
T
G
D
E
D
Q
Site 71
T580
P
R
A
P
E
S
D
T
G
D
E
D
Q
D
Q
Site 72
T591
D
Q
D
Q
E
R
D
T
V
F
L
K
D
N
H
Site 73
S607
A
I
E
R
K
C
S
S
I
T
V
S
S
T
S
Site 74
T609
E
R
K
C
S
S
I
T
V
S
S
T
S
S
L
Site 75
S611
K
C
S
S
I
T
V
S
S
T
S
S
L
E
A
Site 76
S612
C
S
S
I
T
V
S
S
T
S
S
L
E
A
E
Site 77
Y628
D
F
T
V
I
G
D
Y
H
G
S
A
F
E
D
Site 78
S637
G
S
A
F
E
D
F
S
R
S
L
P
E
L
D
Site 79
S639
A
F
E
D
F
S
R
S
L
P
E
L
D
R
D
Site 80
S648
P
E
L
D
R
D
K
S
D
S
D
T
E
G
L
Site 81
S650
L
D
R
D
K
S
D
S
D
T
E
G
L
L
F
Site 82
T652
R
D
K
S
D
S
D
T
E
G
L
L
F
S
R
Site 83
S667
D
L
N
K
G
A
P
S
Q
D
D
E
S
G
G
Site 84
S672
A
P
S
Q
D
D
E
S
G
G
I
E
D
S
P
Site 85
S678
E
S
G
G
I
E
D
S
P
D
R
G
A
C
S
Site 86
S685
S
P
D
R
G
A
C
S
T
P
D
M
P
Q
F
Site 87
T686
P
D
R
G
A
C
S
T
P
D
M
P
Q
F
E
Site 88
T697
P
Q
F
E
P
V
K
T
E
T
M
T
V
S
S
Site 89
S722
A
V
L
Q
T
R
V
S
A
M
D
N
T
Q
Q
Site 90
T727
R
V
S
A
M
D
N
T
Q
Q
V
D
G
S
A
Site 91
S733
N
T
Q
Q
V
D
G
S
A
S
V
G
R
E
F
Site 92
S735
Q
Q
V
D
G
S
A
S
V
G
R
E
F
I
A
Site 93
T743
V
G
R
E
F
I
A
T
T
P
S
I
T
T
E
Site 94
T744
G
R
E
F
I
A
T
T
P
S
I
T
T
E
T
Site 95
S753
S
I
T
T
E
T
I
S
T
T
M
E
N
S
L
Site 96
T754
I
T
T
E
T
I
S
T
T
M
E
N
S
L
K
Site 97
T755
T
T
E
T
I
S
T
T
M
E
N
S
L
K
S
Site 98
S759
I
S
T
T
M
E
N
S
L
K
S
G
K
G
A
Site 99
S762
T
M
E
N
S
L
K
S
G
K
G
A
A
A
M
Site 100
T778
P
G
P
Q
T
V
A
T
E
I
R
S
L
S
P
Site 101
S782
T
V
A
T
E
I
R
S
L
S
P
I
I
G
K
Site 102
S784
A
T
E
I
R
S
L
S
P
I
I
G
K
D
V
Site 103
S794
I
G
K
D
V
L
T
S
T
Y
G
A
T
A
E
Site 104
T795
G
K
D
V
L
T
S
T
Y
G
A
T
A
E
T
Site 105
Y796
K
D
V
L
T
S
T
Y
G
A
T
A
E
T
L
Site 106
T802
T
Y
G
A
T
A
E
T
L
S
T
S
T
T
T
Site 107
S804
G
A
T
A
E
T
L
S
T
S
T
T
T
H
V
Site 108
T808
E
T
L
S
T
S
T
T
T
H
V
T
K
T
V
Site 109
T814
T
T
T
H
V
T
K
T
V
K
G
G
F
S
E
Site 110
S820
K
T
V
K
G
G
F
S
E
T
R
I
E
K
R
Site 111
Y864
L
V
T
K
A
V
V
Y
R
E
T
D
P
S
P
Site 112
T867
K
A
V
V
Y
R
E
T
D
P
S
P
E
E
R
Site 113
S870
V
Y
R
E
T
D
P
S
P
E
E
R
D
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation