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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM83D
Full Name:
Protein FAM83D
Alias:
C20orf129; CT129; DJ616B8.3; FA83D; Family with sequence similarity 83, member D; Spindle protein CHICA
Type:
Unknown function
Mass (Da):
64424
Number AA:
585
UniProt ID:
Q9H4H8
International Prot ID:
IPI00480103
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
E
V
P
A
A
C
L
S
P
C
G
P
P
N
P
Site 2
T25
P
C
G
P
P
N
P
T
E
L
F
S
E
S
R
Site 3
S29
P
N
P
T
E
L
F
S
E
S
R
R
L
A
L
Site 4
S31
P
T
E
L
F
S
E
S
R
R
L
A
L
E
E
Site 5
S89
A
A
A
A
A
E
D
S
F
G
S
S
H
D
C
Site 6
S92
A
A
E
D
S
F
G
S
S
H
D
C
S
S
G
Site 7
S93
A
E
D
S
F
G
S
S
H
D
C
S
S
G
T
Site 8
S97
F
G
S
S
H
D
C
S
S
G
T
Y
F
P
E
Site 9
S98
G
S
S
H
D
C
S
S
G
T
Y
F
P
E
Q
Site 10
T100
S
H
D
C
S
S
G
T
Y
F
P
E
Q
S
D
Site 11
Y101
H
D
C
S
S
G
T
Y
F
P
E
Q
S
D
L
Site 12
S106
G
T
Y
F
P
E
Q
S
D
L
E
P
P
L
L
Site 13
T129
Q
G
A
Y
R
G
A
T
R
V
E
T
H
F
Q
Site 14
T133
R
G
A
T
R
V
E
T
H
F
Q
P
R
G
A
Site 15
Y146
G
A
G
E
G
G
P
Y
G
C
K
D
A
L
R
Site 16
S158
A
L
R
Q
Q
L
R
S
A
R
E
V
I
A
V
Site 17
T220
P
E
Q
E
K
L
M
T
V
R
T
I
T
G
N
Site 18
T223
E
K
L
M
T
V
R
T
I
T
G
N
I
Y
Y
Site 19
Y229
R
T
I
T
G
N
I
Y
Y
A
R
S
G
T
K
Site 20
Y230
T
I
T
G
N
I
Y
Y
A
R
S
G
T
K
I
Site 21
T235
I
Y
Y
A
R
S
G
T
K
I
I
G
K
V
H
Site 22
S257
G
I
R
V
A
T
G
S
Y
S
F
T
W
T
D
Site 23
S259
R
V
A
T
G
S
Y
S
F
T
W
T
D
G
K
Site 24
T261
A
T
G
S
Y
S
F
T
W
T
D
G
K
L
N
Site 25
T263
G
S
Y
S
F
T
W
T
D
G
K
L
N
S
S
Site 26
S270
T
D
G
K
L
N
S
S
N
L
V
I
L
S
G
Site 27
Y291
D
L
E
F
R
I
L
Y
A
Q
S
K
P
I
S
Site 28
S294
F
R
I
L
Y
A
Q
S
K
P
I
S
P
K
L
Site 29
S298
Y
A
Q
S
K
P
I
S
P
K
L
L
S
H
F
Site 30
S303
P
I
S
P
K
L
L
S
H
F
Q
S
S
N
K
Site 31
S307
K
L
L
S
H
F
Q
S
S
N
K
F
D
H
L
Site 32
T315
S
N
K
F
D
H
L
T
N
R
K
P
Q
S
K
Site 33
S321
L
T
N
R
K
P
Q
S
K
E
L
T
L
G
N
Site 34
T325
K
P
Q
S
K
E
L
T
L
G
N
L
L
R
M
Site 35
S338
R
M
R
L
A
R
L
S
S
T
P
R
K
A
D
Site 36
S339
M
R
L
A
R
L
S
S
T
P
R
K
A
D
L
Site 37
T340
R
L
A
R
L
S
S
T
P
R
K
A
D
L
D
Site 38
S365
R
K
P
H
D
C
E
S
S
T
V
S
E
E
D
Site 39
S366
K
P
H
D
C
E
S
S
T
V
S
E
E
D
Y
Site 40
T367
P
H
D
C
E
S
S
T
V
S
E
E
D
Y
F
Site 41
S369
D
C
E
S
S
T
V
S
E
E
D
Y
F
S
S
Site 42
Y373
S
T
V
S
E
E
D
Y
F
S
S
H
R
D
E
Site 43
S375
V
S
E
E
D
Y
F
S
S
H
R
D
E
L
Q
Site 44
S376
S
E
E
D
Y
F
S
S
H
R
D
E
L
Q
S
Site 45
S383
S
H
R
D
E
L
Q
S
R
K
A
I
D
A
A
Site 46
S403
G
E
E
M
P
G
L
S
V
S
E
V
G
T
Q
Site 47
S405
E
M
P
G
L
S
V
S
E
V
G
T
Q
T
S
Site 48
S431
V
I
T
R
I
A
S
S
Q
T
T
I
W
S
R
Site 49
T434
R
I
A
S
S
Q
T
T
I
W
S
R
S
T
T
Site 50
S437
S
S
Q
T
T
I
W
S
R
S
T
T
T
Q
T
Site 51
T440
T
T
I
W
S
R
S
T
T
T
Q
T
D
M
D
Site 52
T441
T
I
W
S
R
S
T
T
T
Q
T
D
M
D
E
Site 53
T456
N
I
L
F
P
R
G
T
Q
S
T
E
G
S
P
Site 54
S458
L
F
P
R
G
T
Q
S
T
E
G
S
P
V
S
Site 55
T459
F
P
R
G
T
Q
S
T
E
G
S
P
V
S
K
Site 56
S462
G
T
Q
S
T
E
G
S
P
V
S
K
M
S
V
Site 57
S465
S
T
E
G
S
P
V
S
K
M
S
V
S
R
S
Site 58
S468
G
S
P
V
S
K
M
S
V
S
R
S
S
S
L
Site 59
S470
P
V
S
K
M
S
V
S
R
S
S
S
L
K
S
Site 60
S472
S
K
M
S
V
S
R
S
S
S
L
K
S
S
S
Site 61
S473
K
M
S
V
S
R
S
S
S
L
K
S
S
S
S
Site 62
S474
M
S
V
S
R
S
S
S
L
K
S
S
S
S
V
Site 63
S477
S
R
S
S
S
L
K
S
S
S
S
V
S
S
Q
Site 64
S478
R
S
S
S
L
K
S
S
S
S
V
S
S
Q
G
Site 65
S479
S
S
S
L
K
S
S
S
S
V
S
S
Q
G
S
Site 66
S480
S
S
L
K
S
S
S
S
V
S
S
Q
G
S
V
Site 67
S482
L
K
S
S
S
S
V
S
S
Q
G
S
V
A
S
Site 68
S483
K
S
S
S
S
V
S
S
Q
G
S
V
A
S
S
Site 69
S486
S
S
V
S
S
Q
G
S
V
A
S
S
T
G
S
Site 70
S489
S
S
Q
G
S
V
A
S
S
T
G
S
P
A
S
Site 71
S490
S
Q
G
S
V
A
S
S
T
G
S
P
A
S
I
Site 72
T491
Q
G
S
V
A
S
S
T
G
S
P
A
S
I
R
Site 73
S493
S
V
A
S
S
T
G
S
P
A
S
I
R
T
T
Site 74
S496
S
S
T
G
S
P
A
S
I
R
T
T
D
F
H
Site 75
T500
S
P
A
S
I
R
T
T
D
F
H
N
P
G
Y
Site 76
Y507
T
D
F
H
N
P
G
Y
P
K
Y
L
G
T
P
Site 77
Y510
H
N
P
G
Y
P
K
Y
L
G
T
P
H
L
E
Site 78
T513
G
Y
P
K
Y
L
G
T
P
H
L
E
L
Y
L
Site 79
Y519
G
T
P
H
L
E
L
Y
L
S
D
S
L
R
N
Site 80
S521
P
H
L
E
L
Y
L
S
D
S
L
R
N
L
N
Site 81
S523
L
E
L
Y
L
S
D
S
L
R
N
L
N
K
E
Site 82
S550
N
H
M
L
A
M
L
S
R
R
T
L
F
T
E
Site 83
T553
L
A
M
L
S
R
R
T
L
F
T
E
N
H
L
Site 84
T556
L
S
R
R
T
L
F
T
E
N
H
L
G
L
H
Site 85
S564
E
N
H
L
G
L
H
S
G
N
F
S
R
V
N
Site 86
Y581
A
V
R
D
V
A
L
Y
P
S
Y
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation