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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRDM12
Full Name:
PR domain zinc finger protein 12
Alias:
PR domain-containing protein 12
Type:
Mass (Da):
40403
Number AA:
367
UniProt ID:
Q9H4Q4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
D
I
L
H
S
F
L
Y
G
R
W
R
N
V
L
Site 2
S54
E
Q
L
F
E
D
K
S
H
H
A
S
P
K
T
Site 3
S58
E
D
K
S
H
H
A
S
P
K
T
A
F
T
A
Site 4
S71
T
A
E
V
L
A
Q
S
F
S
G
E
V
Q
K
Site 5
S73
E
V
L
A
Q
S
F
S
G
E
V
Q
K
L
S
Site 6
S80
S
G
E
V
Q
K
L
S
S
L
V
L
P
A
E
Site 7
T118
G
T
E
M
G
P
F
T
G
R
V
I
A
P
E
Site 8
T145
E
V
F
N
E
D
G
T
V
R
Y
F
I
D
A
Site 9
Y148
N
E
D
G
T
V
R
Y
F
I
D
A
S
Q
E
Site 10
S254
I
C
H
R
G
F
N
S
R
S
N
L
R
S
H
Site 11
S256
H
R
G
F
N
S
R
S
N
L
R
S
H
M
R
Site 12
S260
N
S
R
S
N
L
R
S
H
M
R
I
H
T
L
Site 13
T266
R
S
H
M
R
I
H
T
L
D
K
P
F
V
C
Site 14
S281
R
F
C
N
R
R
F
S
Q
S
S
T
L
R
N
Site 15
S283
C
N
R
R
F
S
Q
S
S
T
L
R
N
H
V
Site 16
S284
N
R
R
F
S
Q
S
S
T
L
R
N
H
V
R
Site 17
T285
R
R
F
S
Q
S
S
T
L
R
N
H
V
R
L
Site 18
T294
R
N
H
V
R
L
H
T
G
E
R
P
Y
K
C
Site 19
Y299
L
H
T
G
E
R
P
Y
K
C
Q
V
C
Q
S
Site 20
S309
Q
V
C
Q
S
A
Y
S
Q
L
A
G
L
R
A
Site 21
S320
G
L
R
A
H
Q
K
S
A
R
H
R
P
P
S
Site 22
S327
S
A
R
H
R
P
P
S
T
A
L
Q
A
H
S
Site 23
S334
S
T
A
L
Q
A
H
S
P
A
L
P
A
P
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation