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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL31
Full Name:
Kelch-like protein 31
Alias:
BTB and kelch domain-containing protein 6;Kelch repeat and BTB domain-containing protein 1;Kelch-like protein KLHL
Type:
Mass (Da):
70246
Number AA:
634
UniProt ID:
Q9H511
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S48
N
G
L
S
C
I
S
S
E
L
T
D
A
S
Y
Site 2
T51
S
C
I
S
S
E
L
T
D
A
S
Y
G
P
N
Site 3
S54
S
S
E
L
T
D
A
S
Y
G
P
N
L
L
E
Site 4
Y55
S
E
L
T
D
A
S
Y
G
P
N
L
L
E
G
Site 5
S64
P
N
L
L
E
G
L
S
K
M
R
Q
E
N
F
Site 6
T81
D
L
V
I
G
T
K
T
K
S
F
D
V
H
K
Site 7
S83
V
I
G
T
K
T
K
S
F
D
V
H
K
S
V
Site 8
S89
K
S
F
D
V
H
K
S
V
M
A
S
C
S
E
Site 9
Y99
A
S
C
S
E
Y
F
Y
N
I
L
K
K
D
P
Site 10
S107
N
I
L
K
K
D
P
S
I
Q
R
V
D
L
N
Site 11
S205
N
F
L
E
F
A
E
S
D
Q
F
M
K
L
T
Site 12
T212
S
D
Q
F
M
K
L
T
F
E
Q
I
N
E
L
Site 13
Y250
F
D
Q
K
R
V
K
Y
A
A
D
L
L
S
N
Site 14
S264
N
I
R
F
G
T
I
S
A
Q
D
L
V
N
Y
Site 15
Y271
S
A
Q
D
L
V
N
Y
V
Q
S
V
P
R
M
Site 16
S306
Y
H
Q
N
T
L
Q
S
R
R
T
R
I
R
G
Site 17
T309
N
T
L
Q
S
R
R
T
R
I
R
G
G
C
R
Site 18
T328
V
G
G
R
P
G
L
T
E
K
S
L
S
R
D
Site 19
S331
R
P
G
L
T
E
K
S
L
S
R
D
I
L
Y
Site 20
S333
G
L
T
E
K
S
L
S
R
D
I
L
Y
R
D
Site 21
Y338
S
L
S
R
D
I
L
Y
R
D
P
E
N
G
W
Site 22
S346
R
D
P
E
N
G
W
S
K
L
T
E
M
P
A
Site 23
T349
E
N
G
W
S
K
L
T
E
M
P
A
K
S
F
Site 24
S413
N
Q
K
R
T
H
F
S
L
S
V
F
N
G
L
Site 25
Y422
S
V
F
N
G
L
V
Y
A
A
G
G
R
N
A
Site 26
S432
G
G
R
N
A
E
G
S
L
A
S
L
E
C
Y
Site 27
S435
N
A
E
G
S
L
A
S
L
E
C
Y
V
P
S
Site 28
Y439
S
L
A
S
L
E
C
Y
V
P
S
T
N
Q
W
Site 29
T450
T
N
Q
W
Q
P
K
T
P
L
E
V
A
R
C
Site 30
S482
I
A
N
A
Y
S
R
S
V
C
A
Y
D
P
A
Site 31
Y486
Y
S
R
S
V
C
A
Y
D
P
A
S
D
S
W
Site 32
S490
V
C
A
Y
D
P
A
S
D
S
W
Q
E
L
P
Site 33
S492
A
Y
D
P
A
S
D
S
W
Q
E
L
P
N
L
Site 34
T501
Q
E
L
P
N
L
S
T
P
R
G
W
H
C
A
Site 35
T534
G
E
R
V
D
V
L
T
V
E
C
Y
S
P
A
Site 36
Y538
D
V
L
T
V
E
C
Y
S
P
A
T
G
Q
W
Site 37
S546
S
P
A
T
G
Q
W
S
Y
A
A
P
L
Q
V
Site 38
Y547
P
A
T
G
Q
W
S
Y
A
A
P
L
Q
V
G
Site 39
Y568
S
A
L
H
G
R
A
Y
L
V
G
G
W
N
E
Site 40
T604
D
D
E
L
P
E
A
T
V
G
V
S
C
C
T
Site 41
S622
P
N
N
V
T
R
E
S
R
A
S
S
V
S
S
Site 42
S625
V
T
R
E
S
R
A
S
S
V
S
S
V
P
V
Site 43
S626
T
R
E
S
R
A
S
S
V
S
S
V
P
V
S
Site 44
S628
E
S
R
A
S
S
V
S
S
V
P
V
S
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation