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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SUV39H2
Full Name:
Histone-lysine N-methyltransferase SUV39H2
Alias:
EC 2.1.1.43; H3-K9-HMTase 2; Histone H3-K9 methyltransferase 2; Histone-lysine N-methyltransferase; KMT1B; Lysine N-methyltransferase 1B; Su(var)3-9 homologue 2; Suppressor of variegation 3-9 homologue 2; SUV92
Type:
Mass (Da):
46682
Number AA:
410
UniProt ID:
Q9H5I1
International Prot ID:
IPI00002929
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000775
GO:0000785
GO:0000790
Uniprot
OncoNet
Molecular Function:
GO:0003682
GO:0003824
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006325
GO:0006333
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T33
L
C
R
K
E
K
L
T
C
K
S
I
G
I
T
Site 2
S36
K
E
K
L
T
C
K
S
I
G
I
T
K
R
N
Site 3
T40
T
C
K
S
I
G
I
T
K
R
N
L
N
N
Y
Site 4
Y47
T
K
R
N
L
N
N
Y
E
V
E
Y
L
C
D
Site 5
Y51
L
N
N
Y
E
V
E
Y
L
C
D
Y
K
V
V
Site 6
Y55
E
V
E
Y
L
C
D
Y
K
V
V
K
D
M
E
Site 7
Y63
K
V
V
K
D
M
E
Y
Y
L
V
K
W
K
G
Site 8
Y64
V
V
K
D
M
E
Y
Y
L
V
K
W
K
G
W
Site 9
S94
P
L
L
L
Q
Q
F
S
N
D
K
H
N
Y
L
Site 10
Y100
F
S
N
D
K
H
N
Y
L
S
Q
V
K
K
G
Site 11
S102
N
D
K
H
N
Y
L
S
Q
V
K
K
G
K
A
Site 12
T111
V
K
K
G
K
A
I
T
P
K
D
N
N
K
T
Site 13
T118
T
P
K
D
N
N
K
T
L
K
P
A
I
A
E
Site 14
S167
V
D
L
E
G
P
P
S
D
F
Y
Y
I
N
E
Site 15
Y170
E
G
P
P
S
D
F
Y
Y
I
N
E
Y
K
P
Site 16
Y171
G
P
P
S
D
F
Y
Y
I
N
E
Y
K
P
A
Site 17
Y175
D
F
Y
Y
I
N
E
Y
K
P
A
P
G
I
S
Site 18
Y212
E
A
G
V
L
L
A
Y
N
K
N
Q
Q
I
K
Site 19
T224
Q
I
K
I
P
P
G
T
P
I
Y
E
C
N
S
Site 20
Y227
I
P
P
G
T
P
I
Y
E
C
N
S
R
C
Q
Site 21
S251
V
Q
K
G
T
Q
Y
S
L
C
I
F
R
T
S
Site 22
T267
G
R
G
W
G
V
K
T
L
V
K
I
K
R
M
Site 23
S287
Y
V
G
E
V
I
T
S
E
E
A
E
R
R
G
Site 24
Y297
A
E
R
R
G
Q
F
Y
D
N
K
G
I
T
Y
Site 25
T303
F
Y
D
N
K
G
I
T
Y
L
F
D
L
D
Y
Site 26
Y310
T
Y
L
F
D
L
D
Y
E
S
D
E
F
T
V
Site 27
S312
L
F
D
L
D
Y
E
S
D
E
F
T
V
D
A
Site 28
T316
D
Y
E
S
D
E
F
T
V
D
A
A
R
Y
G
Site 29
T369
I
N
A
G
E
E
L
T
F
D
Y
Q
M
K
G
Site 30
Y372
G
E
E
L
T
F
D
Y
Q
M
K
G
S
G
D
Site 31
S377
F
D
Y
Q
M
K
G
S
G
D
I
S
S
D
S
Site 32
S381
M
K
G
S
G
D
I
S
S
D
S
I
D
H
S
Site 33
S382
K
G
S
G
D
I
S
S
D
S
I
D
H
S
P
Site 34
S384
S
G
D
I
S
S
D
S
I
D
H
S
P
A
K
Site 35
S388
S
S
D
S
I
D
H
S
P
A
K
K
R
V
R
Site 36
T396
P
A
K
K
R
V
R
T
V
C
K
C
G
A
V
Site 37
T404
V
C
K
C
G
A
V
T
C
R
G
Y
L
N
_
Site 38
Y408
G
A
V
T
C
R
G
Y
L
N
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation