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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM38B
Full Name:
Protein PIEZO2
Alias:
Protein FAM38B
Type:
Mass (Da):
62671
Number AA:
544
UniProt ID:
Q9H5I5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y31
V
P
I
K
Q
F
F
Y
N
L
I
H
P
E
Y
Site 2
Y38
Y
N
L
I
H
P
E
Y
S
A
V
T
D
V
Y
Site 3
T76
H
S
A
A
A
D
I
T
S
S
L
S
E
D
Q
Site 4
S80
A
D
I
T
S
S
L
S
E
D
Q
V
P
G
P
Site 5
Y103
A
K
V
N
G
R
V
Y
L
I
I
N
S
I
K
Site 6
T137
F
F
I
L
P
G
V
T
E
R
K
F
S
Q
N
Site 7
S142
G
V
T
E
R
K
F
S
Q
N
L
V
A
Q
L
Site 8
Y169
A
Y
Q
I
R
C
G
Y
P
T
R
V
L
G
N
Site 9
T179
R
V
L
G
N
F
L
T
K
S
Y
N
Y
V
N
Site 10
S218
T
D
T
T
L
S
L
S
S
W
I
C
V
E
D
Site 11
S247
E
K
P
I
F
T
M
S
A
Q
Q
S
Q
L
K
Site 12
S251
F
T
M
S
A
Q
Q
S
Q
L
K
V
M
D
Q
Site 13
T272
I
Q
A
F
S
R
D
T
G
A
M
Q
F
L
E
Site 14
T287
N
Y
E
K
E
D
I
T
V
A
E
L
E
G
N
Site 15
S297
E
L
E
G
N
S
N
S
L
W
T
I
S
P
P
Site 16
S302
S
N
S
L
W
T
I
S
P
P
S
K
Q
K
M
Site 17
S318
H
E
L
L
D
P
N
S
S
F
S
V
V
F
S
Site 18
S333
W
S
I
Q
R
N
L
S
L
G
A
K
S
E
I
Site 19
T342
G
A
K
S
E
I
A
T
D
K
L
S
F
P
L
Site 20
S346
E
I
A
T
D
K
L
S
F
P
L
K
N
I
T
Site 21
S365
A
K
M
I
A
G
N
S
T
E
S
S
K
T
P
Site 22
T366
K
M
I
A
G
N
S
T
E
S
S
K
T
P
V
Site 23
S369
A
G
N
S
T
E
S
S
K
T
P
V
T
I
E
Site 24
T371
N
S
T
E
S
S
K
T
P
V
T
I
E
K
I
Site 25
T374
E
S
S
K
T
P
V
T
I
E
K
I
Y
P
Y
Site 26
Y379
P
V
T
I
E
K
I
Y
P
Y
Y
V
K
A
P
Site 27
Y381
T
I
E
K
I
Y
P
Y
Y
V
K
A
P
S
D
Site 28
Y382
I
E
K
I
Y
P
Y
Y
V
K
A
P
S
D
S
Site 29
S387
P
Y
Y
V
K
A
P
S
D
S
N
S
K
P
I
Site 30
S389
Y
V
K
A
P
S
D
S
N
S
K
P
I
K
Q
Site 31
S391
K
A
P
S
D
S
N
S
K
P
I
K
Q
L
L
Site 32
S399
K
P
I
K
Q
L
L
S
E
N
N
F
M
D
I
Site 33
Y408
Y
F
I
N
Y
F
F
Y
K
F
G
L
E
T
C
Site 34
T415
I
I
L
S
R
D
N
T
T
K
Y
N
S
E
W
Site 35
Y418
S
R
D
N
T
T
K
Y
N
S
E
W
W
V
L
Site 36
Y433
N
L
T
G
N
R
I
Y
N
P
N
S
Q
A
L
Site 37
S437
N
R
I
Y
N
P
N
S
Q
A
L
E
L
V
V
Site 38
S450
V
V
F
N
D
K
V
S
P
P
S
L
G
F
L
Site 39
S453
N
D
K
V
S
P
P
S
L
G
F
L
A
G
Y
Site 40
T512
D
I
F
L
V
R
E
T
G
E
L
E
L
E
E
Site 41
S531
K
L
I
F
L
Y
R
S
P
E
T
M
I
K
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation