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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
THAP9
Full Name:
THAP domain-containing protein 9
Alias:
Type:
Mass (Da):
103411
Number AA:
903
UniProt ID:
Q9H5L6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
V
G
C
S
T
R
D
T
V
L
S
R
E
R
G
Site 2
S18
S
T
R
D
T
V
L
S
R
E
R
G
L
S
F
Site 3
S24
L
S
R
E
R
G
L
S
F
H
Q
F
P
T
D
Site 4
S49
V
N
R
V
D
P
R
S
K
K
I
W
I
P
G
Site 5
S69
C
S
K
H
F
Q
E
S
D
F
E
S
Y
G
I
Site 6
S73
F
Q
E
S
D
F
E
S
Y
G
I
R
R
K
L
Site 7
S89
K
G
A
V
P
S
V
S
L
Y
K
I
P
Q
G
Site 8
S116
K
Q
P
L
P
D
N
S
Q
E
V
A
T
E
D
Site 9
Y126
V
A
T
E
D
H
N
Y
S
L
K
T
P
L
T
Site 10
S127
A
T
E
D
H
N
Y
S
L
K
T
P
L
T
I
Site 11
T130
D
H
N
Y
S
L
K
T
P
L
T
I
G
A
E
Site 12
S155
V
S
K
K
R
L
I
S
V
K
N
Y
R
M
I
Site 13
Y159
R
L
I
S
V
K
N
Y
R
M
I
K
K
R
K
Site 14
Y200
S
D
F
K
W
E
L
Y
N
W
R
E
T
D
E
Site 15
T205
E
L
Y
N
W
R
E
T
D
E
Y
S
A
E
M
Site 16
Y208
N
W
R
E
T
D
E
Y
S
A
E
M
K
Q
F
Site 17
T218
E
M
K
Q
F
A
C
T
L
Y
L
C
S
S
K
Site 18
Y227
Y
L
C
S
S
K
V
Y
D
Y
V
R
K
I
L
Site 19
Y229
C
S
S
K
V
Y
D
Y
V
R
K
I
L
K
L
Site 20
T244
P
H
S
S
I
L
R
T
W
L
S
K
C
Q
P
Site 21
S247
S
I
L
R
T
W
L
S
K
C
Q
P
S
P
G
Site 22
S252
W
L
S
K
C
Q
P
S
P
G
F
N
S
N
I
Site 23
S257
Q
P
S
P
G
F
N
S
N
I
F
S
F
L
Q
Site 24
S261
G
F
N
S
N
I
F
S
F
L
Q
R
R
V
E
Site 25
Y274
V
E
N
G
D
Q
L
Y
Q
Y
C
S
L
L
I
Site 26
Y276
N
G
D
Q
L
Y
Q
Y
C
S
L
L
I
K
S
Site 27
S295
Q
Q
L
Q
W
D
P
S
S
H
S
L
Q
G
F
Site 28
S296
Q
L
Q
W
D
P
S
S
H
S
L
Q
G
F
M
Site 29
T315
G
K
L
D
A
D
E
T
P
L
A
S
E
T
V
Site 30
Y339
H
W
R
T
P
L
G
Y
F
F
V
N
R
A
S
Site 31
T398
D
G
D
D
M
K
C
T
F
Q
H
P
S
S
S
Site 32
S403
K
C
T
F
Q
H
P
S
S
S
S
Q
Q
I
A
Site 33
S404
C
T
F
Q
H
P
S
S
S
S
Q
Q
I
A
Y
Site 34
S405
T
F
Q
H
P
S
S
S
S
Q
Q
I
A
Y
F
Site 35
S406
F
Q
H
P
S
S
S
S
Q
Q
I
A
Y
F
F
Site 36
Y411
S
S
S
Q
Q
I
A
Y
F
F
D
S
C
H
L
Site 37
S456
A
L
E
E
Q
E
L
S
N
M
E
R
I
P
S
Site 38
S463
S
N
M
E
R
I
P
S
T
L
A
N
L
K
N
Site 39
T464
N
M
E
R
I
P
S
T
L
A
N
L
K
N
H
Site 40
Y527
I
F
N
S
R
N
C
Y
G
K
G
L
K
G
P
Site 41
T539
K
G
P
L
L
P
E
T
Y
S
K
I
N
H
V
Site 42
T556
E
A
K
T
I
F
V
T
L
S
D
T
S
N
N
Site 43
S558
K
T
I
F
V
T
L
S
D
T
S
N
N
Q
I
Site 44
S583
G
F
L
L
N
A
E
S
L
K
W
L
Y
Q
N
Site 45
Y588
A
E
S
L
K
W
L
Y
Q
N
Y
V
F
P
K
Site 46
Y591
L
K
W
L
Y
Q
N
Y
V
F
P
K
V
M
P
Site 47
Y605
P
F
P
Y
L
L
T
Y
K
F
S
H
D
H
L
Site 48
S662
K
V
S
I
F
D
I
S
I
A
R
R
K
D
L
Site 49
T673
R
K
D
L
A
L
W
T
V
Q
R
Q
Y
G
V
Site 50
Y678
L
W
T
V
Q
R
Q
Y
G
V
S
V
T
K
T
Site 51
S681
V
Q
R
Q
Y
G
V
S
V
T
K
T
V
F
H
Site 52
S700
C
Q
D
W
S
H
C
S
L
S
E
A
L
L
D
Site 53
S702
D
W
S
H
C
S
L
S
E
A
L
L
D
L
S
Site 54
S709
S
E
A
L
L
D
L
S
D
H
R
R
N
L
I
Site 55
Y718
H
R
R
N
L
I
C
Y
A
G
Y
V
A
N
K
Site 56
Y740
E
D
C
I
T
A
L
Y
A
S
D
L
K
A
S
Site 57
S783
E
R
V
V
R
T
H
S
R
M
A
I
F
E
L
Site 58
Y798
V
S
K
Q
R
E
L
Y
L
Q
Q
K
I
L
C
Site 59
S860
Q
N
P
L
K
H
H
S
E
R
T
D
M
K
T
Site 60
T867
S
E
R
T
D
M
K
T
L
S
R
K
H
W
S
Site 61
S869
R
T
D
M
K
T
L
S
R
K
H
W
S
S
V
Site 62
S875
L
S
R
K
H
W
S
S
V
Q
D
Y
K
C
S
Site 63
Y879
H
W
S
S
V
Q
D
Y
K
C
S
S
F
A
N
Site 64
S883
V
Q
D
Y
K
C
S
S
F
A
N
T
S
S
K
Site 65
T887
K
C
S
S
F
A
N
T
S
S
K
F
R
H
L
Site 66
S889
S
S
F
A
N
T
S
S
K
F
R
H
L
L
S
Site 67
S896
S
K
F
R
H
L
L
S
N
D
G
Y
P
F
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation