KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TFB2M
Full Name:
Dimethyladenosine transferase 2, mitochondrial
Alias:
Hepatitis C virus NS5A-transactivated protein 5;Mitochondrial 12S rRNA dimethylase 2;Mitochondrial transcription factor B2;S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2
Type:
Mass (Da):
45349
Number AA:
396
UniProt ID:
Q9H5Q4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
L
P
R
R
L
R
L
S
A
L
A
G
A
G
R
Site 2
T32
I
L
G
S
E
A
A
T
R
K
H
L
P
A
R
Site 3
S45
A
R
N
H
C
G
L
S
D
S
S
P
Q
L
W
Site 4
S47
N
H
C
G
L
S
D
S
S
P
Q
L
W
P
E
Site 5
S48
H
C
G
L
S
D
S
S
P
Q
L
W
P
E
P
Site 6
S65
R
N
P
P
R
K
A
S
K
A
S
L
D
F
K
Site 7
S68
P
R
K
A
S
K
A
S
L
D
F
K
R
Y
V
Site 8
Y74
A
S
L
D
F
K
R
Y
V
T
D
R
R
L
A
Site 9
T76
L
D
F
K
R
Y
V
T
D
R
R
L
A
E
T
Site 10
T83
T
D
R
R
L
A
E
T
L
A
Q
I
Y
L
G
Site 11
S93
Q
I
Y
L
G
K
P
S
R
P
P
H
L
L
L
Site 12
T128
V
A
L
E
S
D
K
T
F
I
P
H
L
E
S
Site 13
S135
T
F
I
P
H
L
E
S
L
G
K
N
L
D
G
Site 14
S158
F
F
K
L
D
P
R
S
G
G
V
I
K
P
P
Site 15
S168
V
I
K
P
P
A
M
S
S
R
G
L
F
K
N
Site 16
Y209
R
A
L
W
K
L
A
Y
D
L
Y
S
C
T
S
Site 17
Y212
W
K
L
A
Y
D
L
Y
S
C
T
S
I
Y
K
Site 18
Y247
D
P
G
N
P
D
L
Y
H
V
L
S
V
I
W
Site 19
Y274
P
W
S
S
F
D
I
Y
T
R
K
G
P
L
E
Site 20
Y297
D
Q
L
Q
Q
K
L
Y
L
I
Q
M
I
P
R
Site 21
T309
I
P
R
Q
N
L
F
T
K
N
L
T
P
M
N
Site 22
S332
K
H
C
F
G
R
R
S
A
T
V
I
D
H
L
Site 23
T334
C
F
G
R
R
S
A
T
V
I
D
H
L
R
S
Site 24
S341
T
V
I
D
H
L
R
S
L
T
P
L
D
A
R
Site 25
T343
I
D
H
L
R
S
L
T
P
L
D
A
R
D
I
Site 26
T372
M
H
P
Q
D
F
K
T
L
F
E
T
I
E
R
Site 27
T376
D
F
K
T
L
F
E
T
I
E
R
S
K
D
C
Site 28
Y385
E
R
S
K
D
C
A
Y
K
W
L
Y
D
E
T
Site 29
Y389
D
C
A
Y
K
W
L
Y
D
E
T
L
E
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation