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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIF1
Full Name:
ATP-dependent DNA helicase PIF1
Alias:
EC 3.6.1.-; PIF; PIF1 ''to-''DNA helicase; PIF1/RRM3 DNA helicase-like protein
Type:
Helicase, DNA binding protein
Mass (Da):
69799
Number AA:
641
UniProt ID:
Q9H611
International Prot ID:
IPI00017925
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000784
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0043141
GO:0033682
PhosphoSite+
KinaseNET
Biological Process:
GO:0051974
GO:0032204
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
A
G
E
Y
E
D
S
E
L
R
C
R
V
A
Site 2
S27
R
V
A
V
E
E
L
S
P
G
G
Q
P
R
R
Site 3
T40
R
R
R
Q
A
L
R
T
A
E
L
S
L
G
R
Site 4
S44
A
L
R
T
A
E
L
S
L
G
R
N
E
R
R
Site 5
T78
L
R
A
A
R
L
F
T
R
F
A
E
A
G
R
Site 6
S86
R
F
A
E
A
G
R
S
T
L
R
L
P
A
H
Site 7
T87
F
A
E
A
G
R
S
T
L
R
L
P
A
H
D
Site 8
T95
L
R
L
P
A
H
D
T
P
G
A
G
A
V
Q
Site 9
T119
R
L
R
R
F
L
R
T
L
R
L
K
L
A
A
Site 10
S134
A
P
G
P
G
P
A
S
A
R
A
Q
L
L
G
Site 11
T149
P
R
P
R
D
F
V
T
I
S
P
V
Q
P
E
Site 12
S151
P
R
D
F
V
T
I
S
P
V
Q
P
E
E
R
Site 13
T164
E
R
R
L
R
A
A
T
R
V
P
D
T
T
L
Site 14
T169
A
A
T
R
V
P
D
T
T
L
V
K
R
P
V
Site 15
T170
A
T
R
V
P
D
T
T
L
V
K
R
P
V
E
Site 16
T186
Q
A
G
A
E
P
S
T
E
A
P
R
W
P
L
Site 17
S199
P
L
P
V
K
R
L
S
L
P
S
T
K
P
Q
Site 18
S202
V
K
R
L
S
L
P
S
T
K
P
Q
L
S
E
Site 19
T203
K
R
L
S
L
P
S
T
K
P
Q
L
S
E
E
Site 20
S208
P
S
T
K
P
Q
L
S
E
E
Q
A
A
V
L
Site 21
T227
K
G
Q
S
I
F
F
T
G
S
A
G
T
G
K
Site 22
S229
Q
S
I
F
F
T
G
S
A
G
T
G
K
S
Y
Site 23
S235
G
S
A
G
T
G
K
S
Y
L
L
K
R
I
L
Site 24
Y236
S
A
G
T
G
K
S
Y
L
L
K
R
I
L
G
Site 25
S354
L
P
P
V
T
K
G
S
Q
P
P
R
F
C
F
Site 26
S400
A
V
R
L
G
R
C
S
D
E
V
T
R
Q
L
Site 27
T404
G
R
C
S
D
E
V
T
R
Q
L
Q
A
T
A
Site 28
T410
V
T
R
Q
L
Q
A
T
A
S
H
K
V
G
R
Site 29
S412
R
Q
L
Q
A
T
A
S
H
K
V
G
R
D
G
Site 30
S455
H
R
F
E
A
M
D
S
N
P
E
L
A
S
T
Site 31
T462
S
N
P
E
L
A
S
T
L
D
A
Q
C
P
V
Site 32
T530
V
I
H
A
D
R
W
T
V
Q
A
T
G
G
Q
Site 33
S540
A
T
G
G
Q
L
L
S
R
Q
Q
L
P
L
Q
Site 34
T561
I
H
K
S
Q
G
M
T
L
D
C
V
E
I
S
Site 35
S583
G
Q
A
Y
V
A
L
S
R
A
R
S
L
Q
G
Site 36
Y611
D
P
R
V
L
H
F
Y
A
T
L
R
R
G
R
Site 37
T613
R
V
L
H
F
Y
A
T
L
R
R
G
R
S
L
Site 38
S619
A
T
L
R
R
G
R
S
L
S
L
E
S
P
D
Site 39
S621
L
R
R
G
R
S
L
S
L
E
S
P
D
D
D
Site 40
S624
G
R
S
L
S
L
E
S
P
D
D
D
E
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation