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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC86
Full Name:
Coiled-coil domain-containing protein 86
Alias:
CCD86; Coiled-coil domain containing 86; Cytokine-induced protein with coiled-coil domain; FLJ22321; MGC2574
Type:
Ubiquitin conjugating system
Mass (Da):
40236
Number AA:
360
UniProt ID:
Q9H6F5
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0044419
GO:0051704
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
D
T
P
L
R
R
S
R
R
Site 2
S8
M
D
T
P
L
R
R
S
R
R
L
G
G
L
R
Site 3
S18
L
G
G
L
R
P
E
S
P
E
S
L
T
S
V
Site 4
S21
L
R
P
E
S
P
E
S
L
T
S
V
S
R
T
Site 5
T23
P
E
S
P
E
S
L
T
S
V
S
R
T
R
R
Site 6
S24
E
S
P
E
S
L
T
S
V
S
R
T
R
R
A
Site 7
S26
P
E
S
L
T
S
V
S
R
T
R
R
A
L
V
Site 8
T28
S
L
T
S
V
S
R
T
R
R
A
L
V
E
F
Site 9
S37
R
A
L
V
E
F
E
S
N
P
E
E
T
R
E
Site 10
T42
F
E
S
N
P
E
E
T
R
E
P
G
S
P
P
Site 11
S47
E
E
T
R
E
P
G
S
P
P
S
V
Q
R
A
Site 12
S50
R
E
P
G
S
P
P
S
V
Q
R
A
G
L
G
Site 13
S58
V
Q
R
A
G
L
G
S
P
E
R
P
P
K
T
Site 14
T65
S
P
E
R
P
P
K
T
S
P
G
S
P
R
L
Site 15
S66
P
E
R
P
P
K
T
S
P
G
S
P
R
L
Q
Site 16
S69
P
P
K
T
S
P
G
S
P
R
L
Q
Q
G
A
Site 17
S80
Q
Q
G
A
G
L
E
S
P
Q
G
Q
P
E
P
Site 18
S91
Q
P
E
P
G
A
A
S
P
Q
R
Q
Q
D
L
Site 19
S102
Q
Q
D
L
H
L
E
S
P
Q
R
Q
P
E
Y
Site 20
Y109
S
P
Q
R
Q
P
E
Y
S
P
E
S
P
R
C
Site 21
S110
P
Q
R
Q
P
E
Y
S
P
E
S
P
R
C
Q
Site 22
S113
Q
P
E
Y
S
P
E
S
P
R
C
Q
P
K
P
Site 23
S121
P
R
C
Q
P
K
P
S
E
E
A
P
K
C
S
Site 24
S128
S
E
E
A
P
K
C
S
Q
D
Q
G
V
L
A
Site 25
T146
A
Q
N
K
E
E
L
T
P
G
A
P
Q
H
Q
Site 26
S160
Q
L
P
P
V
P
G
S
P
E
P
Y
P
G
Q
Site 27
Y164
V
P
G
S
P
E
P
Y
P
G
Q
Q
A
P
G
Site 28
T182
S
Q
P
L
L
E
L
T
P
R
A
P
G
S
P
Site 29
S188
L
T
P
R
A
P
G
S
P
R
G
Q
H
E
P
Site 30
S196
P
R
G
Q
H
E
P
S
K
P
P
P
A
G
E
Site 31
T204
K
P
P
P
A
G
E
T
V
T
G
G
F
G
A
Site 32
S217
G
A
K
K
R
K
G
S
S
S
Q
A
P
A
S
Site 33
S218
A
K
K
R
K
G
S
S
S
Q
A
P
A
S
K
Site 34
S219
K
K
R
K
G
S
S
S
Q
A
P
A
S
K
K
Site 35
S224
S
S
S
Q
A
P
A
S
K
K
L
N
K
E
E
Site 36
S242
I
P
K
G
K
P
K
S
G
R
V
W
K
D
R
Site 37
S250
G
R
V
W
K
D
R
S
K
K
R
F
S
Q
M
Site 38
S255
D
R
S
K
K
R
F
S
Q
M
L
Q
D
K
P
Site 39
S266
Q
D
K
P
L
R
T
S
W
Q
R
K
M
K
E
Site 40
S338
A
K
K
K
Q
L
R
S
I
E
K
R
D
T
L
Site 41
T344
R
S
I
E
K
R
D
T
L
A
L
L
Q
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation