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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C14orf169
Full Name:
Lysine-specific demethylase NO66
Alias:
chromosome 14 open reading frame 169; FLJ21802; NO66; nucleolar protein 66
Type:
Mass (Da):
71090
Number AA:
641
UniProt ID:
Q9H6W3
International Prot ID:
IPI00002879
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005654
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
D
G
L
Q
A
S
A
G
P
L
R
R
G
Site 2
S26
R
R
K
P
Q
P
H
S
G
S
V
L
A
L
P
Site 3
S28
K
P
Q
P
H
S
G
S
V
L
A
L
P
L
R
Site 4
S45
K
I
R
K
Q
L
R
S
V
V
S
R
M
A
A
Site 5
S48
K
Q
L
R
S
V
V
S
R
M
A
A
L
R
T
Site 6
T57
M
A
A
L
R
T
Q
T
L
P
S
E
N
S
E
Site 7
S60
L
R
T
Q
T
L
P
S
E
N
S
E
E
S
R
Site 8
S63
Q
T
L
P
S
E
N
S
E
E
S
R
V
E
S
Site 9
S66
P
S
E
N
S
E
E
S
R
V
E
S
T
A
D
Site 10
S70
S
E
E
S
R
V
E
S
T
A
D
D
L
G
D
Site 11
Y97
D
A
A
R
R
E
P
Y
G
H
L
G
P
A
E
Site 12
S109
P
A
E
L
L
E
A
S
P
A
A
R
S
L
Q
Site 13
S114
E
A
S
P
A
A
R
S
L
Q
T
P
S
A
R
Site 14
T117
P
A
A
R
S
L
Q
T
P
S
A
R
L
V
P
Site 15
S119
A
R
S
L
Q
T
P
S
A
R
L
V
P
A
S
Site 16
T166
Q
S
S
G
A
P
A
T
A
S
G
P
Q
V
D
Site 17
S168
S
G
A
P
A
T
A
S
G
P
Q
V
D
N
T
Site 18
T175
S
G
P
Q
V
D
N
T
G
G
E
P
A
W
D
Site 19
S183
G
G
E
P
A
W
D
S
P
L
R
R
V
L
A
Site 20
S197
A
E
L
N
R
I
P
S
S
R
R
R
A
A
R
Site 21
S198
E
L
N
R
I
P
S
S
R
R
R
A
A
R
L
Site 22
Y219
P
M
P
P
D
H
F
Y
R
R
L
W
E
R
E
Site 23
T236
L
V
R
R
Q
D
H
T
Y
Y
Q
G
L
F
S
Site 24
Y237
V
R
R
Q
D
H
T
Y
Y
Q
G
L
F
S
T
Site 25
Y238
R
R
Q
D
H
T
Y
Y
Q
G
L
F
S
T
A
Site 26
S243
T
Y
Y
Q
G
L
F
S
T
A
D
L
D
S
M
Site 27
S249
F
S
T
A
D
L
D
S
M
L
R
N
E
E
V
Site 28
T274
Y
I
N
G
R
R
E
T
L
N
P
P
G
R
A
Site 29
S321
V
L
Q
E
Q
F
G
S
M
A
G
S
N
V
Y
Site 30
S325
Q
F
G
S
M
A
G
S
N
V
Y
L
T
P
P
Site 31
Y328
S
M
A
G
S
N
V
Y
L
T
P
P
N
S
Q
Site 32
T330
A
G
S
N
V
Y
L
T
P
P
N
S
Q
G
F
Site 33
S334
V
Y
L
T
P
P
N
S
Q
G
F
A
P
H
Y
Site 34
Y341
S
Q
G
F
A
P
H
Y
D
D
I
E
A
F
V
Site 35
Y360
G
R
K
L
W
R
V
Y
R
P
R
A
P
T
E
Site 36
T366
V
Y
R
P
R
A
P
T
E
E
L
A
L
T
S
Site 37
T372
P
T
E
E
L
A
L
T
S
S
P
N
F
S
Q
Site 38
S373
T
E
E
L
A
L
T
S
S
P
N
F
S
Q
D
Site 39
S374
E
E
L
A
L
T
S
S
P
N
F
S
Q
D
D
Site 40
S378
L
T
S
S
P
N
F
S
Q
D
D
L
G
E
P
Site 41
S415
E
C
Q
D
G
V
H
S
L
H
L
T
L
S
T
Site 42
T419
G
V
H
S
L
H
L
T
L
S
T
Y
Q
R
N
Site 43
Y423
L
H
L
T
L
S
T
Y
Q
R
N
T
W
G
D
Site 44
T427
L
S
T
Y
Q
R
N
T
W
G
D
F
L
E
A
Site 45
Y461
L
P
R
D
F
M
D
Y
M
G
A
Q
H
S
D
Site 46
S467
D
Y
M
G
A
Q
H
S
D
S
K
D
P
R
R
Site 47
S469
M
G
A
Q
H
S
D
S
K
D
P
R
R
T
A
Site 48
T475
D
S
K
D
P
R
R
T
A
F
M
E
K
V
R
Site 49
S509
A
K
D
F
I
H
D
S
L
P
P
V
L
T
D
Site 50
T515
D
S
L
P
P
V
L
T
D
R
E
R
A
L
S
Site 51
S522
T
D
R
E
R
A
L
S
V
Y
G
L
P
I
R
Site 52
Y524
R
E
R
A
L
S
V
Y
G
L
P
I
R
W
E
Site 53
Y568
E
G
G
H
L
F
L
Y
Y
T
V
E
N
S
R
Site 54
Y569
G
G
H
L
F
L
Y
Y
T
V
E
N
S
R
V
Site 55
T570
G
H
L
F
L
Y
Y
T
V
E
N
S
R
V
Y
Site 56
Y577
T
V
E
N
S
R
V
Y
H
L
E
E
P
K
C
Site 57
Y588
E
P
K
C
L
E
I
Y
P
Q
Q
A
D
A
M
Site 58
S615
V
G
D
L
P
C
D
S
V
E
D
Q
L
S
L
Site 59
S621
D
S
V
E
D
Q
L
S
L
A
T
T
L
Y
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation