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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPF2
Full Name:
Ribosome production factor 2 homolog
Alias:
Brix domain-containing protein 1;Ribosome biogenesis protein RPF2 homolog
Type:
Uncharacterized
Mass (Da):
35583
Number AA:
306
UniProt ID:
Q9H7B2
International Prot ID:
IPI00396329
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
D
R
V
V
K
P
K
T
K
R
A
K
R
F
L
Site 2
T44
K
G
G
N
A
N
A
T
V
T
K
V
L
K
D
Site 3
Y53
T
K
V
L
K
D
V
Y
A
L
K
K
P
Y
G
Site 4
Y59
V
Y
A
L
K
K
P
Y
G
V
L
Y
K
K
K
Site 5
Y63
K
K
P
Y
G
V
L
Y
K
K
K
N
I
T
R
Site 6
T69
L
Y
K
K
K
N
I
T
R
P
F
E
D
Q
T
Site 7
T76
T
R
P
F
E
D
Q
T
S
L
E
F
F
S
K
Site 8
S77
R
P
F
E
D
Q
T
S
L
E
F
F
S
K
K
Site 9
S82
Q
T
S
L
E
F
F
S
K
K
S
D
C
S
L
Site 10
S88
F
S
K
K
S
D
C
S
L
F
M
F
G
S
H
Site 11
Y109
N
L
V
I
G
R
M
Y
D
Y
H
V
L
D
M
Site 12
S126
L
G
I
E
N
F
V
S
L
K
D
I
K
N
S
Site 13
S133
S
L
K
D
I
K
N
S
K
C
P
E
G
T
K
Site 14
T153
A
G
D
D
F
D
V
T
E
D
Y
R
R
L
K
Site 15
Y156
D
F
D
V
T
E
D
Y
R
R
L
K
S
L
L
Site 16
S161
E
D
Y
R
R
L
K
S
L
L
I
D
F
F
R
Site 17
T187
L
E
Y
V
L
H
F
T
A
L
N
G
K
I
Y
Site 18
Y194
T
A
L
N
G
K
I
Y
F
R
S
Y
K
L
L
Site 19
S197
N
G
K
I
Y
F
R
S
Y
K
L
L
L
K
K
Site 20
Y198
G
K
I
Y
F
R
S
Y
K
L
L
L
K
K
S
Site 21
S205
Y
K
L
L
L
K
K
S
G
C
R
T
P
R
I
Site 22
T209
L
K
K
S
G
C
R
T
P
R
I
E
L
E
E
Site 23
S220
E
L
E
E
M
G
P
S
L
D
L
V
L
R
R
Site 24
T228
L
D
L
V
L
R
R
T
H
L
A
S
D
D
L
Site 25
S232
L
R
R
T
H
L
A
S
D
D
L
Y
K
L
S
Site 26
Y236
H
L
A
S
D
D
L
Y
K
L
S
M
K
M
P
Site 27
S239
S
D
D
L
Y
K
L
S
M
K
M
P
K
A
L
Site 28
S255
P
K
K
K
K
N
I
S
H
D
T
F
G
T
T
Site 29
T258
K
K
N
I
S
H
D
T
F
G
T
T
Y
G
R
Site 30
Y263
H
D
T
F
G
T
T
Y
G
R
I
H
M
Q
K
Site 31
S274
H
M
Q
K
Q
D
L
S
K
L
Q
T
R
K
M
Site 32
T278
Q
D
L
S
K
L
Q
T
R
K
M
K
G
L
K
Site 33
T293
K
R
P
A
E
R
I
T
E
D
H
E
K
K
S
Site 34
S300
T
E
D
H
E
K
K
S
K
R
I
K
K
N
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation