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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMYD3
Full Name:
SET and MYND domain-containing protein 3
Alias:
ZMYND1, ZNFN3A1
Type:
Mass (Da):
49083
Number AA:
428
UniProt ID:
Q9H7B4
International Prot ID:
Isoform1 - IPI00165073
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0018024
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
L
K
V
E
K
F
A
T
A
K
R
G
N
G
L
Site 2
T22
G
N
G
L
R
A
V
T
P
L
R
P
G
E
L
Site 3
Y38
F
R
S
D
P
L
A
Y
T
V
C
K
G
S
R
Site 4
T39
R
S
D
P
L
A
Y
T
V
C
K
G
S
R
G
Site 5
S63
K
E
K
L
M
R
C
S
Q
C
R
V
A
K
Y
Site 6
Y70
S
Q
C
R
V
A
K
Y
C
S
A
K
C
Q
K
Site 7
Y97
L
K
S
C
K
P
R
Y
P
P
D
S
V
R
L
Site 8
S101
K
P
R
Y
P
P
D
S
V
R
L
L
G
R
V
Site 9
S118
K
L
M
D
G
A
P
S
E
S
E
K
L
Y
S
Site 10
S120
M
D
G
A
P
S
E
S
E
K
L
Y
S
F
Y
Site 11
Y124
P
S
E
S
E
K
L
Y
S
F
Y
D
L
E
S
Site 12
S125
S
E
S
E
K
L
Y
S
F
Y
D
L
E
S
N
Site 13
Y127
S
E
K
L
Y
S
F
Y
D
L
E
S
N
I
N
Site 14
T150
G
L
R
Q
L
V
M
T
F
Q
H
F
M
R
E
Site 15
S163
R
E
E
I
Q
D
A
S
Q
L
P
P
A
F
D
Site 16
S207
S
I
S
L
L
N
H
S
C
D
P
N
C
S
I
Site 17
Y239
G
E
E
L
T
I
C
Y
L
D
M
L
M
T
S
Site 18
S246
Y
L
D
M
L
M
T
S
E
E
R
R
K
Q
L
Site 19
Y257
R
K
Q
L
R
D
Q
Y
C
F
E
C
D
C
F
Site 20
T277
D
K
D
A
D
M
L
T
G
D
E
Q
V
W
K
Site 21
S289
V
W
K
E
V
Q
E
S
L
K
K
I
E
E
L
Site 22
S317
Q
A
I
I
S
S
N
S
E
R
L
P
D
I
N
Site 23
Y350
L
L
E
E
A
L
F
Y
G
T
R
T
M
E
P
Site 24
T354
A
L
F
Y
G
T
R
T
M
E
P
Y
R
I
F
Site 25
Y358
G
T
R
T
M
E
P
Y
R
I
F
F
P
G
S
Site 26
S365
Y
R
I
F
F
P
G
S
H
P
V
R
G
V
Q
Site 27
T403
A
F
D
I
M
R
V
T
H
G
R
E
H
S
L
Site 28
S409
V
T
H
G
R
E
H
S
L
I
E
D
L
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation