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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYNC1
Full Name:
Syncoilin
Alias:
SYNCOILIN; Syncoilin intermediate filament 1; Syncoilin, intermediate filament protein
Type:
Mass (Da):
55551
Number AA:
483
UniProt ID:
Q9H7C4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005882
GO:0048471
GO:0005882
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
L
L
A
Q
R
K
K
T
R
V
E
A
N
S
P
Site 2
S27
K
T
R
V
E
A
N
S
P
L
P
K
N
S
G
Site 3
S35
P
L
P
K
N
S
G
S
L
N
E
A
E
A
L
Site 4
T47
E
A
L
N
P
E
V
T
L
S
S
E
G
S
L
Site 5
S49
L
N
P
E
V
T
L
S
S
E
G
S
L
N
L
Site 6
Y61
L
N
L
E
D
I
L
Y
L
E
D
T
G
D
L
Site 7
T65
D
I
L
Y
L
E
D
T
G
D
L
D
E
T
L
Site 8
T71
D
T
G
D
L
D
E
T
L
Y
V
Q
E
T
E
Site 9
Y73
G
D
L
D
E
T
L
Y
V
Q
E
T
E
K
A
Site 10
Y85
E
K
A
E
E
A
L
Y
I
E
E
A
M
Q
P
Site 11
T107
E
P
G
N
P
E
E
T
V
C
V
E
E
T
T
Site 12
T132
P
V
E
P
G
K
P
T
S
P
E
H
V
V
Y
Site 13
S133
V
E
P
G
K
P
T
S
P
E
H
V
V
Y
E
Site 14
Y139
T
S
P
E
H
V
V
Y
E
G
E
T
V
T
R
Site 15
S150
T
V
T
R
A
E
K
S
N
P
E
E
S
L
R
Site 16
S155
E
K
S
N
P
E
E
S
L
R
A
E
Q
S
P
Site 17
S161
E
S
L
R
A
E
Q
S
P
S
M
E
E
N
L
Site 18
S163
L
R
A
E
Q
S
P
S
M
E
E
N
L
S
I
Site 19
S169
P
S
M
E
E
N
L
S
I
E
D
L
E
L
L
Site 20
Y257
V
T
K
E
C
V
A
Y
Q
Y
Q
L
E
C
R
Site 21
T279
A
D
F
R
E
V
L
T
T
R
A
T
Q
L
S
Site 22
T280
D
F
R
E
V
L
T
T
R
A
T
Q
L
S
E
Site 23
T283
E
V
L
T
T
R
A
T
Q
L
S
E
E
L
A
Site 24
S286
T
T
R
A
T
Q
L
S
E
E
L
A
Q
L
R
Site 25
Y296
L
A
Q
L
R
D
A
Y
Q
K
Q
K
E
Q
L
Site 26
S312
Q
Q
L
E
A
P
P
S
Q
R
D
G
H
F
L
Site 27
S322
D
G
H
F
L
Q
E
S
R
R
L
S
A
Q
F
Site 28
S326
L
Q
E
S
R
R
L
S
A
Q
F
E
N
L
M
Site 29
Y344
R
Q
D
L
E
E
E
Y
E
P
Q
F
L
R
L
Site 30
Y411
R
D
E
E
V
Q
Q
Y
R
E
Q
L
E
E
M
Site 31
S445
E
M
E
Q
L
R
L
S
L
A
E
E
L
S
T
Site 32
S461
K
A
M
L
L
P
K
S
L
E
Q
A
D
A
P
Site 33
S470
E
Q
A
D
A
P
T
S
Q
A
G
G
M
E
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation