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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TDRD3
Full Name:
Tudor domain-containing protein 3
Alias:
FLJ21007; TDR; tudor domain containing 3; Tudor domain containing protein 3
Type:
Translation
Mass (Da):
73185
Number AA:
651
UniProt ID:
Q9H7E2
International Prot ID:
IPI00006571
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003676
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
L
R
L
Q
M
T
D
G
H
I
S
C
T
Site 2
S22
A
V
E
F
S
Y
M
S
K
I
S
L
N
T
P
Site 3
S25
F
S
Y
M
S
K
I
S
L
N
T
P
P
G
T
Site 4
T28
M
S
K
I
S
L
N
T
P
P
G
T
K
V
K
Site 5
T32
S
L
N
T
P
P
G
T
K
V
K
L
S
G
I
Site 6
S73
E
K
W
E
L
Q
R
S
L
S
K
H
N
R
S
Site 7
S75
W
E
L
Q
R
S
L
S
K
H
N
R
S
N
I
Site 8
S80
S
L
S
K
H
N
R
S
N
I
G
T
E
G
G
Site 9
T84
H
N
R
S
N
I
G
T
E
G
G
P
P
P
F
Site 10
S100
P
F
G
Q
K
C
V
S
H
V
Q
V
D
S
R
Site 11
T114
R
E
L
D
R
R
K
T
L
Q
V
T
M
P
V
Site 12
T118
R
R
K
T
L
Q
V
T
M
P
V
K
P
T
N
Site 13
T135
D
E
F
E
K
Q
R
T
A
A
I
A
E
V
A
Site 14
S144
A
I
A
E
V
A
K
S
K
E
T
K
T
F
G
Site 15
T147
E
V
A
K
S
K
E
T
K
T
F
G
G
G
G
Site 16
T149
A
K
S
K
E
T
K
T
F
G
G
G
G
G
G
Site 17
S159
G
G
G
G
G
A
R
S
N
L
N
M
N
A
A
Site 18
S179
E
V
L
Q
K
E
K
S
T
K
S
E
G
K
H
Site 19
S182
Q
K
E
K
S
T
K
S
E
G
K
H
E
G
V
Site 20
Y190
E
G
K
H
E
G
V
Y
R
E
L
V
D
E
K
Site 21
T203
E
K
A
L
K
H
I
T
E
M
G
F
S
K
E
Site 22
S208
H
I
T
E
M
G
F
S
K
E
A
S
R
Q
A
Site 23
S212
M
G
F
S
K
E
A
S
R
Q
A
L
M
D
N
Site 24
S256
K
G
R
G
R
I
R
S
E
D
E
E
D
L
G
Site 25
S268
D
L
G
N
A
R
P
S
A
P
S
T
L
F
D
Site 26
S271
N
A
R
P
S
A
P
S
T
L
F
D
F
L
E
Site 27
T272
A
R
P
S
A
P
S
T
L
F
D
F
L
E
S
Site 28
T283
F
L
E
S
K
M
G
T
L
N
V
E
E
P
K
Site 29
S291
L
N
V
E
E
P
K
S
Q
P
Q
Q
L
H
Q
Site 30
Y301
Q
Q
L
H
Q
G
Q
Y
R
S
S
N
T
E
Q
Site 31
S304
H
Q
G
Q
Y
R
S
S
N
T
E
Q
N
G
V
Site 32
T325
R
H
P
P
R
N
D
T
R
Q
P
R
N
E
K
Site 33
S340
P
P
R
F
Q
R
D
S
Q
N
S
K
S
V
L
Site 34
S343
F
Q
R
D
S
Q
N
S
K
S
V
L
E
G
S
Site 35
S345
R
D
S
Q
N
S
K
S
V
L
E
G
S
G
L
Site 36
S350
S
K
S
V
L
E
G
S
G
L
P
R
N
R
G
Site 37
S358
G
L
P
R
N
R
G
S
E
R
P
S
T
S
S
Site 38
S362
N
R
G
S
E
R
P
S
T
S
S
V
S
E
V
Site 39
T363
R
G
S
E
R
P
S
T
S
S
V
S
E
V
W
Site 40
S364
G
S
E
R
P
S
T
S
S
V
S
E
V
W
A
Site 41
S365
S
E
R
P
S
T
S
S
V
S
E
V
W
A
E
Site 42
S367
R
P
S
T
S
S
V
S
E
V
W
A
E
D
R
Site 43
Y381
R
I
K
C
D
R
P
Y
S
R
Y
D
R
T
K
Site 44
S382
I
K
C
D
R
P
Y
S
R
Y
D
R
T
K
D
Site 45
Y384
C
D
R
P
Y
S
R
Y
D
R
T
K
D
T
S
Site 46
T387
P
Y
S
R
Y
D
R
T
K
D
T
S
Y
P
L
Site 47
T390
R
Y
D
R
T
K
D
T
S
Y
P
L
G
S
Q
Site 48
S391
Y
D
R
T
K
D
T
S
Y
P
L
G
S
Q
H
Site 49
Y392
D
R
T
K
D
T
S
Y
P
L
G
S
Q
H
S
Site 50
S396
D
T
S
Y
P
L
G
S
Q
H
S
D
G
A
F
Site 51
S399
Y
P
L
G
S
Q
H
S
D
G
A
F
K
K
R
Site 52
S409
A
F
K
K
R
D
N
S
M
Q
S
R
S
G
K
Site 53
S412
K
R
D
N
S
M
Q
S
R
S
G
K
G
P
S
Site 54
S414
D
N
S
M
Q
S
R
S
G
K
G
P
S
F
A
Site 55
S419
S
R
S
G
K
G
P
S
F
A
E
A
K
E
N
Site 56
Y435
L
P
Q
G
S
V
D
Y
N
N
Q
K
R
G
K
Site 57
S445
Q
K
R
G
K
R
E
S
Q
T
S
I
P
D
Y
Site 58
T447
R
G
K
R
E
S
Q
T
S
I
P
D
Y
F
Y
Site 59
S448
G
K
R
E
S
Q
T
S
I
P
D
Y
F
Y
D
Site 60
Y452
S
Q
T
S
I
P
D
Y
F
Y
D
R
K
S
Q
Site 61
Y454
T
S
I
P
D
Y
F
Y
D
R
K
S
Q
T
I
Site 62
T479
E
K
H
F
N
V
N
T
D
Y
Q
N
P
V
R
Site 63
Y481
H
F
N
V
N
T
D
Y
Q
N
P
V
R
S
N
Site 64
S487
D
Y
Q
N
P
V
R
S
N
S
F
I
G
V
P
Site 65
S489
Q
N
P
V
R
S
N
S
F
I
G
V
P
N
G
Site 66
T517
I
K
P
A
G
P
V
T
A
V
P
C
D
D
K
Site 67
Y527
P
C
D
D
K
I
F
Y
N
S
G
P
K
R
R
Site 68
S529
D
D
K
I
F
Y
N
S
G
P
K
R
R
S
G
Site 69
S535
N
S
G
P
K
R
R
S
G
P
I
K
P
E
K
Site 70
Y552
E
S
S
I
P
M
E
Y
A
K
M
W
K
P
G
Site 71
Y566
G
D
E
C
F
A
L
Y
W
E
D
N
K
F
Y
Site 72
Y597
K
F
I
D
Y
G
N
Y
E
E
V
L
L
S
N
Site 73
S603
N
Y
E
E
V
L
L
S
N
I
K
P
I
Q
T
Site 74
T618
E
A
W
E
E
E
G
T
Y
D
Q
T
L
E
F
Site 75
Y619
A
W
E
E
E
G
T
Y
D
Q
T
L
E
F
R
Site 76
T622
E
E
G
T
Y
D
Q
T
L
E
F
R
R
G
G
Site 77
S636
G
D
G
Q
P
R
R
S
T
R
P
T
Q
Q
F
Site 78
T637
D
G
Q
P
R
R
S
T
R
P
T
Q
Q
F
Y
Site 79
T640
P
R
R
S
T
R
P
T
Q
Q
F
Y
Q
P
P
Site 80
Y644
T
R
P
T
Q
Q
F
Y
Q
P
P
R
A
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation