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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP13A3
Full Name:
Probable cation-transporting ATPase 13A3
Alias:
AFURS1; AT133; ATPase family homolog up-regulated in senescence cells 1; ATPase family homologue up-regulated in senescence cells 1; ATPase family up regulated in senescence cells; ATPase type 13A3; Cation-transporting ATPase 13A3
Type:
Transporter; Hydrolase; EC 3.6.3.-
Mass (Da):
138043
Number AA:
1226
UniProt ID:
Q9H7F0
International Prot ID:
IPI00234337
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0015662
GO:0000287
PhosphoSite+
KinaseNET
Biological Process:
GO:0006754
GO:0006812
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
D
R
E
E
R
K
T
I
N
Q
G
Q
E
D
Site 2
Y20
Q
E
D
E
M
E
I
Y
G
Y
N
L
S
R
W
Site 3
Y22
D
E
M
E
I
Y
G
Y
N
L
S
R
W
K
L
Site 4
T93
I
R
V
L
S
L
E
T
Y
P
V
S
S
P
K
Site 5
Y94
R
V
L
S
L
E
T
Y
P
V
S
S
P
K
S
Site 6
S97
S
L
E
T
Y
P
V
S
S
P
K
S
M
S
N
Site 7
S98
L
E
T
Y
P
V
S
S
P
K
S
M
S
N
K
Site 8
S101
Y
P
V
S
S
P
K
S
M
S
N
K
L
S
N
Site 9
S103
V
S
S
P
K
S
M
S
N
K
L
S
N
G
H
Site 10
S107
K
S
M
S
N
K
L
S
N
G
H
A
V
C
L
Site 11
S127
E
E
N
R
H
R
I
S
K
Y
S
Q
T
E
S
Site 12
Y129
N
R
H
R
I
S
K
Y
S
Q
T
E
S
Q
Q
Site 13
S130
R
H
R
I
S
K
Y
S
Q
T
E
S
Q
Q
I
Site 14
T132
R
I
S
K
Y
S
Q
T
E
S
Q
Q
I
R
Y
Site 15
S134
S
K
Y
S
Q
T
E
S
Q
Q
I
R
Y
F
T
Site 16
Y139
T
E
S
Q
Q
I
R
Y
F
T
H
H
S
V
K
Site 17
T141
S
Q
Q
I
R
Y
F
T
H
H
S
V
K
Y
F
Site 18
S167
K
G
L
D
E
G
V
S
C
T
S
I
Y
E
K
Site 19
Y172
G
V
S
C
T
S
I
Y
E
K
H
S
A
G
L
Site 20
T180
E
K
H
S
A
G
L
T
K
G
M
H
A
Y
R
Site 21
Y191
H
A
Y
R
K
L
L
Y
G
V
N
E
I
A
V
Site 22
S273
T
H
S
T
V
R
V
S
V
C
R
V
N
E
E
Site 23
S286
E
E
I
E
E
I
F
S
T
D
L
V
P
G
D
Site 24
T330
T
G
E
S
V
P
V
T
K
T
N
L
P
N
P
Site 25
T332
E
S
V
P
V
T
K
T
N
L
P
N
P
S
V
Site 26
S338
K
T
N
L
P
N
P
S
V
D
V
K
G
I
G
Site 27
Y349
K
G
I
G
D
E
L
Y
N
P
E
T
H
K
R
Site 28
T353
D
E
L
Y
N
P
E
T
H
K
R
H
T
L
F
Site 29
T358
P
E
T
H
K
R
H
T
L
F
C
G
T
T
V
Site 30
T387
V
V
R
T
G
F
S
T
S
K
G
Q
L
V
R
Site 31
Y398
Q
L
V
R
S
I
L
Y
P
K
P
T
D
F
K
Site 32
T402
S
I
L
Y
P
K
P
T
D
F
K
L
Y
R
D
Site 33
Y407
K
P
T
D
F
K
L
Y
R
D
A
Y
L
F
L
Site 34
Y468
A
M
T
A
G
I
V
Y
A
Q
R
R
L
K
K
Site 35
T500
N
L
V
C
F
D
K
T
G
T
L
T
E
D
G
Site 36
S523
V
E
N
A
R
F
L
S
P
E
E
N
V
C
N
Site 37
S556
T
K
I
E
G
V
L
S
G
D
P
L
D
L
K
Site 38
T589
L
H
N
R
I
M
P
T
V
V
R
P
P
K
Q
Site 39
S601
P
K
Q
L
L
P
E
S
T
P
A
G
N
Q
E
Site 40
T602
K
Q
L
L
P
E
S
T
P
A
G
N
Q
E
M
Site 41
S629
I
V
R
Q
F
P
F
S
S
A
L
Q
R
M
S
Site 42
S630
V
R
Q
F
P
F
S
S
A
L
Q
R
M
S
V
Site 43
Y650
G
D
R
K
M
D
A
Y
M
K
G
A
P
E
A
Site 44
T666
A
G
L
C
K
P
E
T
V
P
V
D
F
Q
N
Site 45
T698
R
K
L
E
S
K
L
T
W
H
K
V
Q
N
I
Site 46
T730
Q
N
K
L
K
Q
E
T
P
A
V
L
E
D
L
Site 47
S817
P
V
K
L
V
H
D
S
L
E
D
L
Q
M
T
Site 48
Y826
E
D
L
Q
M
T
R
Y
H
F
A
M
N
G
K
Site 49
T865
R
M
A
P
D
Q
K
T
Q
L
I
E
A
L
Q
Site 50
S899
K
R
A
H
G
G
I
S
L
S
E
L
E
A
S
Site 51
S909
E
L
E
A
S
V
A
S
P
F
T
S
K
T
P
Site 52
S913
S
V
A
S
P
F
T
S
K
T
P
S
I
S
C
Site 53
T915
A
S
P
F
T
S
K
T
P
S
I
S
C
V
P
Site 54
S917
P
F
T
S
K
T
P
S
I
S
C
V
P
N
L
Site 55
S919
T
S
K
T
P
S
I
S
C
V
P
N
L
I
R
Site 56
T1047
K
S
D
A
C
N
T
T
G
S
G
F
W
N
S
Site 57
S1054
T
G
S
G
F
W
N
S
S
H
V
D
N
E
T
Site 58
T1061
S
S
H
V
D
N
E
T
E
L
D
E
H
N
I
Site 59
Y1071
D
E
H
N
I
Q
N
Y
E
N
T
T
V
F
F
Site 60
Y1102
K
P
F
R
Q
P
C
Y
K
N
Y
F
F
V
F
Site 61
S1163
V
S
I
T
V
E
E
S
V
D
R
W
G
K
C
Site 62
T1182
A
L
G
C
R
K
K
T
P
K
A
K
Y
M
Y
Site 63
Y1189
T
P
K
A
K
Y
M
Y
L
A
Q
E
L
L
V
Site 64
S1219
A
L
V
K
E
N
G
S
C
Q
I
I
T
I
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation