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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYST1
Full Name:
Probable histone acetyltransferase MYST1
Alias:
FLJ14040; HMOF; KAT8; MOF; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST protein 1
Type:
Acetyltransferase; EC 2.3.1.48
Mass (Da):
52403
Number AA:
458
UniProt ID:
Q9H7Z6
International Prot ID:
IPI00550352
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003682
GO:0004402
GO:0008134
PhosphoSite+
KinaseNET
Biological Process:
GO:0006333
GO:0016573
GO:0030099
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
A
A
E
G
T
A
P
S
P
G
R
V
S
P
P
Site 2
S42
A
P
S
P
G
R
V
S
P
P
T
P
A
R
G
Site 3
T45
P
G
R
V
S
P
P
T
P
A
R
G
E
P
E
Site 4
T54
A
R
G
E
P
E
V
T
V
E
I
G
E
T
Y
Site 5
T60
V
T
V
E
I
G
E
T
Y
L
C
R
R
P
D
Site 6
Y61
T
V
E
I
G
E
T
Y
L
C
R
R
P
D
S
Site 7
S68
Y
L
C
R
R
P
D
S
T
W
H
S
A
E
V
Site 8
T69
L
C
R
R
P
D
S
T
W
H
S
A
E
V
I
Site 9
S72
R
P
D
S
T
W
H
S
A
E
V
I
Q
S
R
Site 10
Y90
Q
E
G
R
E
E
F
Y
V
H
Y
V
G
F
N
Site 11
Y93
R
E
E
F
Y
V
H
Y
V
G
F
N
R
R
L
Site 12
T112
D
K
N
R
L
A
L
T
K
T
V
K
D
A
V
Site 13
T114
N
R
L
A
L
T
K
T
V
K
D
A
V
Q
K
Site 14
Y126
V
Q
K
N
S
E
K
Y
L
S
E
L
A
E
Q
Site 15
S128
K
N
S
E
K
Y
L
S
E
L
A
E
Q
P
E
Site 16
T139
E
Q
P
E
R
K
I
T
R
N
Q
K
R
K
H
Site 17
T162
T
Y
A
E
M
D
P
T
T
A
A
L
E
K
E
Site 18
T163
Y
A
E
M
D
P
T
T
A
A
L
E
K
E
H
Site 19
T174
E
K
E
H
E
A
I
T
K
V
K
Y
V
D
K
Site 20
Y178
E
A
I
T
K
V
K
Y
V
D
K
I
H
I
G
Site 21
Y187
D
K
I
H
I
G
N
Y
E
I
D
A
W
Y
F
Site 22
Y193
N
Y
E
I
D
A
W
Y
F
S
P
F
P
E
D
Site 23
Y201
F
S
P
F
P
E
D
Y
G
K
Q
P
K
L
W
Site 24
Y216
L
C
E
Y
C
L
K
Y
M
K
Y
E
K
S
Y
Site 25
Y219
Y
C
L
K
Y
M
K
Y
E
K
S
Y
R
F
H
Site 26
S244
G
K
E
I
Y
R
K
S
N
I
S
V
Y
E
V
Site 27
S247
I
Y
R
K
S
N
I
S
V
Y
E
V
D
G
K
Site 28
Y249
R
K
S
N
I
S
V
Y
E
V
D
G
K
D
H
Site 29
Y259
D
G
K
D
H
K
I
Y
C
Q
N
L
C
L
L
Site 30
T275
K
L
F
L
D
H
K
T
L
Y
F
D
V
E
P
Site 31
Y277
F
L
D
H
K
T
L
Y
F
D
V
E
P
F
V
Site 32
Y286
D
V
E
P
F
V
F
Y
I
L
T
E
V
D
R
Site 33
Y301
Q
G
A
H
I
V
G
Y
F
S
K
E
K
E
S
Site 34
S303
A
H
I
V
G
Y
F
S
K
E
K
E
S
P
D
Site 35
S308
Y
F
S
K
E
K
E
S
P
D
G
N
N
V
A
Site 36
T319
N
N
V
A
C
I
L
T
L
P
P
Y
Q
R
R
Site 37
Y323
C
I
L
T
L
P
P
Y
Q
R
R
G
Y
G
K
Site 38
Y328
P
P
Y
Q
R
R
G
Y
G
K
F
L
I
A
F
Site 39
S344
Y
E
L
S
K
L
E
S
T
V
G
S
P
E
K
Site 40
T345
E
L
S
K
L
E
S
T
V
G
S
P
E
K
P
Site 41
S348
K
L
E
S
T
V
G
S
P
E
K
P
L
S
D
Site 42
S354
G
S
P
E
K
P
L
S
D
L
G
K
L
S
Y
Site 43
S360
L
S
D
L
G
K
L
S
Y
R
S
Y
W
S
W
Site 44
Y361
S
D
L
G
K
L
S
Y
R
S
Y
W
S
W
V
Site 45
S363
L
G
K
L
S
Y
R
S
Y
W
S
W
V
L
L
Site 46
Y364
G
K
L
S
Y
R
S
Y
W
S
W
V
L
L
E
Site 47
T379
I
L
R
D
F
R
G
T
L
S
I
K
D
L
S
Site 48
S381
R
D
F
R
G
T
L
S
I
K
D
L
S
Q
M
Site 49
S386
T
L
S
I
K
D
L
S
Q
M
T
S
I
T
Q
Site 50
S390
K
D
L
S
Q
M
T
S
I
T
Q
N
D
I
I
Site 51
S398
I
T
Q
N
D
I
I
S
T
L
Q
S
L
N
M
Site 52
Y408
Q
S
L
N
M
V
K
Y
W
K
G
Q
H
V
I
Site 53
T418
G
Q
H
V
I
C
V
T
P
K
L
V
E
E
H
Site 54
S428
L
V
E
E
H
L
K
S
A
Q
Y
K
K
P
P
Site 55
Y431
E
H
L
K
S
A
Q
Y
K
K
P
P
I
T
V
Site 56
T437
Q
Y
K
K
P
P
I
T
V
D
S
V
C
L
K
Site 57
S456
K
H
K
Q
V
K
L
S
K
K
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation