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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBE2Z
Full Name:
Ubiquitin-conjugating enzyme E2 Z
Alias:
EC 6.3.2.19; Flj13855; Hoys7; Uba6-specific E2 conjugating enzyme 1; Ube2z; Ubiquitin carrier protein Z; Ubiquitin-conjugating enzyme e2z; Ubiquitin-protein ligase Z; Use1
Type:
Ubiquitin conjugating system, Ubiquitin ligase, Ligase
Mass (Da):
38210
Number AA:
354
UniProt ID:
Q9H832
International Prot ID:
IPI00011996
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0019941
GO:0043687
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
S
P
T
E
E
A
A
T
A
G
A
G
A
A
G
Site 2
S81
A
H
G
A
A
L
L
S
H
W
D
P
T
L
S
Site 3
T86
L
L
S
H
W
D
P
T
L
S
S
D
W
D
G
Site 4
S89
H
W
D
P
T
L
S
S
D
W
D
G
E
R
T
Site 5
S110
R
I
K
R
D
I
M
S
I
Y
K
E
P
P
P
Site 6
Y112
K
R
D
I
M
S
I
Y
K
E
P
P
P
G
M
Site 7
T125
G
M
F
V
V
P
D
T
V
D
M
T
K
I
H
Site 8
Y158
V
F
R
C
P
P
D
Y
P
I
H
P
P
R
V
Site 9
T169
P
P
R
V
K
L
M
T
T
G
N
N
T
V
R
Site 10
T174
L
M
T
T
G
N
N
T
V
R
F
N
P
N
F
Site 11
T194
V
C
L
S
I
L
G
T
W
T
G
P
A
W
S
Site 12
S201
T
W
T
G
P
A
W
S
P
A
Q
S
I
S
S
Site 13
Y222
S
L
M
T
E
N
P
Y
H
N
E
P
G
F
E
Site 14
S274
L
R
G
V
M
E
K
S
F
L
E
Y
Y
D
F
Site 15
Y278
M
E
K
S
F
L
E
Y
Y
D
F
Y
E
V
A
Site 16
Y279
E
K
S
F
L
E
Y
Y
D
F
Y
E
V
A
C
Site 17
Y282
F
L
E
Y
Y
D
F
Y
E
V
A
C
K
D
R
Site 18
Y310
E
K
R
G
H
F
D
Y
Q
S
L
L
M
R
L
Site 19
S312
R
G
H
F
D
Y
Q
S
L
L
M
R
L
G
L
Site 20
S337
N
E
N
A
E
M
D
S
D
S
S
S
S
G
T
Site 21
S339
N
A
E
M
D
S
D
S
S
S
S
G
T
E
T
Site 22
S340
A
E
M
D
S
D
S
S
S
S
G
T
E
T
D
Site 23
S341
E
M
D
S
D
S
S
S
S
G
T
E
T
D
L
Site 24
S342
M
D
S
D
S
S
S
S
G
T
E
T
D
L
H
Site 25
T344
S
D
S
S
S
S
G
T
E
T
D
L
H
G
S
Site 26
T346
S
S
S
S
G
T
E
T
D
L
H
G
S
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation