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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
YY1AP1
Full Name:
YY1-associated protein 1
Alias:
FLJ10875; FLJ13914; HCCA1; HCCA2; Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-associated 2; YAP; YY1 associated 1; YY1AP; YY1-associated; YY1-associated 1; YYAP1
Type:
Cytoplasm, Nucleus protein
Mass (Da):
87944
Number AA:
796
UniProt ID:
Q9H869
International Prot ID:
IPI00640856
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
A
S
R
S
A
A
A
T
N
P
G
S
R
L
T
Site 2
S16
A
A
A
T
N
P
G
S
R
L
T
R
W
P
P
Site 3
T19
T
N
P
G
S
R
L
T
R
W
P
P
P
D
K
Site 4
S30
P
P
D
K
R
E
G
S
A
V
D
P
G
K
R
Site 5
S39
V
D
P
G
K
R
R
S
L
A
A
T
P
S
S
Site 6
T43
K
R
R
S
L
A
A
T
P
S
S
S
L
P
C
Site 7
T51
P
S
S
S
L
P
C
T
L
I
A
L
G
L
R
Site 8
T103
E
P
Q
A
N
F
N
T
P
Q
A
L
R
F
E
Site 9
T157
Q
C
K
E
V
H
Q
T
L
I
L
D
P
A
Q
Site 10
S197
P
N
L
N
P
E
A
S
S
T
R
I
C
L
K
Site 11
S198
N
L
N
P
E
A
S
S
T
R
I
C
L
K
E
Site 12
T199
L
N
P
E
A
S
S
T
R
I
C
L
K
E
L
Site 13
S213
L
G
T
F
A
Q
S
S
I
A
L
H
H
Q
Y
Site 14
Y220
S
I
A
L
H
H
Q
Y
N
P
K
F
Q
T
L
Site 15
T245
Q
L
I
E
D
F
S
T
H
V
S
I
D
C
S
Site 16
S248
E
D
F
S
T
H
V
S
I
D
C
S
P
H
K
Site 17
S252
T
H
V
S
I
D
C
S
P
H
K
T
V
K
K
Site 18
T256
I
D
C
S
P
H
K
T
V
K
K
T
A
N
E
Site 19
T260
P
H
K
T
V
K
K
T
A
N
E
F
P
C
L
Site 20
S291
P
E
L
L
P
V
C
S
L
K
A
K
N
P
Q
Site 21
Y311
T
K
A
E
D
N
K
Y
L
L
T
C
K
T
A
Site 22
T317
K
Y
L
L
T
C
K
T
A
R
Q
L
T
V
R
Site 23
T322
C
K
T
A
R
Q
L
T
V
R
I
K
N
L
N
Site 24
S380
L
P
F
W
L
K
A
S
L
P
S
I
Q
E
E
Site 25
T405
V
G
N
M
T
G
T
T
E
I
N
S
D
Q
G
Site 26
S409
T
G
T
T
E
I
N
S
D
Q
G
L
E
K
D
Site 27
S418
Q
G
L
E
K
D
N
S
E
L
G
S
E
T
R
Site 28
S422
K
D
N
S
E
L
G
S
E
T
R
Y
P
L
L
Site 29
T424
N
S
E
L
G
S
E
T
R
Y
P
L
L
L
P
Site 30
Y426
E
L
G
S
E
T
R
Y
P
L
L
L
P
K
G
Site 31
S455
K
A
W
R
Q
K
R
S
S
V
L
K
P
L
L
Site 32
S456
A
W
R
Q
K
R
S
S
V
L
K
P
L
L
I
Site 33
S466
K
P
L
L
I
Q
P
S
P
S
L
Q
P
S
F
Site 34
S468
L
L
I
Q
P
S
P
S
L
Q
P
S
F
N
P
Site 35
S472
P
S
P
S
L
Q
P
S
F
N
P
G
K
T
P
Site 36
T478
P
S
F
N
P
G
K
T
P
A
Q
S
T
H
S
Site 37
S485
T
P
A
Q
S
T
H
S
E
A
P
P
S
K
M
Site 38
S490
T
H
S
E
A
P
P
S
K
M
V
L
R
I
P
Site 39
T504
P
H
P
I
Q
P
A
T
V
L
Q
T
V
P
G
Site 40
S518
G
V
P
P
L
G
V
S
G
G
E
S
F
E
S
Site 41
S525
S
G
G
E
S
F
E
S
P
A
A
L
P
A
M
Site 42
S539
M
P
P
E
A
R
T
S
F
P
L
S
E
S
Q
Site 43
S543
A
R
T
S
F
P
L
S
E
S
Q
T
L
L
S
Site 44
S545
T
S
F
P
L
S
E
S
Q
T
L
L
S
S
A
Site 45
S550
S
E
S
Q
T
L
L
S
S
A
P
V
P
K
V
Site 46
S551
E
S
Q
T
L
L
S
S
A
P
V
P
K
V
M
Site 47
S564
V
M
M
P
S
P
A
S
S
M
F
R
K
P
Y
Site 48
S565
M
M
P
S
P
A
S
S
M
F
R
K
P
Y
V
Site 49
Y571
S
S
M
F
R
K
P
Y
V
R
R
R
P
S
K
Site 50
S577
P
Y
V
R
R
R
P
S
K
R
R
G
A
R
A
Site 51
S665
S
V
S
P
L
I
V
S
G
N
S
V
N
L
P
Site 52
S675
S
V
N
L
P
I
P
S
T
P
E
D
K
A
H
Site 53
T676
V
N
L
P
I
P
S
T
P
E
D
K
A
H
M
Site 54
S711
K
L
E
P
Q
E
L
S
P
L
S
A
T
V
F
Site 55
S714
P
Q
E
L
S
P
L
S
A
T
V
F
P
K
V
Site 56
T716
E
L
S
P
L
S
A
T
V
F
P
K
V
E
H
Site 57
S724
V
F
P
K
V
E
H
S
P
G
P
P
P
V
D
Site 58
S739
K
Q
C
Q
E
G
L
S
E
N
S
A
Y
R
W
Site 59
Y744
G
L
S
E
N
S
A
Y
R
W
T
V
V
K
T
Site 60
T747
E
N
S
A
Y
R
W
T
V
V
K
T
E
E
G
Site 61
S768
L
P
Q
G
I
Q
E
S
L
N
N
S
S
P
G
Site 62
S772
I
Q
E
S
L
N
N
S
S
P
G
D
L
E
E
Site 63
S773
Q
E
S
L
N
N
S
S
P
G
D
L
E
E
V
Site 64
T789
K
M
E
P
E
D
A
T
E
E
I
S
G
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation