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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNNM2
Full Name:
Metal transporter CNNM2
Alias:
Ancient conserved domain-containing protein 2;Cyclin-M2
Type:
Mass (Da):
96623
Number AA:
875
UniProt ID:
Q9H8M5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
W
K
M
A
A
R
R
S
L
S
A
R
G
R
G
Site 2
S34
M
A
A
R
R
S
L
S
A
R
G
R
G
I
L
Site 3
T82
I
G
L
R
L
E
D
T
N
D
V
S
F
M
E
Site 4
S86
L
E
D
T
N
D
V
S
F
M
E
G
G
A
L
Site 5
S96
E
G
G
A
L
R
V
S
E
R
T
R
V
K
L
Site 6
Y106
T
R
V
K
L
R
V
Y
G
Q
N
I
N
N
E
Site 7
S129
E
H
E
R
R
R
H
S
P
G
E
R
G
L
G
Site 8
S145
P
A
P
P
E
P
D
S
G
P
Q
R
C
G
I
Site 9
S186
P
L
R
K
M
E
K
S
K
S
Y
Y
L
C
T
Site 10
S188
R
K
M
E
K
S
K
S
Y
Y
L
C
T
S
L
Site 11
Y190
M
E
K
S
K
S
Y
Y
L
C
T
S
L
S
T
Site 12
T193
S
K
S
Y
Y
L
C
T
S
L
S
T
P
A
L
Site 13
T407
V
L
G
Q
E
I
G
T
V
Y
N
R
E
K
L
Site 14
Y409
G
Q
E
I
G
T
V
Y
N
R
E
K
L
L
E
Site 15
Y424
M
L
R
V
T
D
P
Y
N
D
L
V
K
E
E
Site 16
T445
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
Site 17
T451
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
Site 18
T469
E
A
I
L
D
F
N
T
M
S
E
I
M
E
S
Site 19
S476
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
Site 20
Y478
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
Site 21
T479
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
Site 22
T509
F
V
D
P
D
D
C
T
P
L
K
T
I
T
K
Site 23
T513
D
D
C
T
P
L
K
T
I
T
K
F
Y
N
H
Site 24
Y518
L
K
T
I
T
K
F
Y
N
H
P
L
H
F
V
Site 25
S543
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
Site 26
S579
V
I
E
E
I
I
K
S
E
I
L
D
E
T
D
Site 27
T585
K
S
E
I
L
D
E
T
D
L
Y
T
D
N
R
Site 28
Y588
I
L
D
E
T
D
L
Y
T
D
N
R
T
K
K
Site 29
T589
L
D
E
T
D
L
Y
T
D
N
R
T
K
K
K
Site 30
S607
R
E
R
K
Q
D
F
S
A
F
K
Q
T
D
S
Site 31
S640
A
T
E
V
E
A
F
S
P
S
Q
M
S
E
K
Site 32
S642
E
V
E
A
F
S
P
S
Q
M
S
E
K
I
L
Site 33
Y664
N
V
I
Q
E
L
K
Y
D
E
K
N
K
K
A
Site 34
Y674
K
N
K
K
A
P
E
Y
Y
L
Y
Q
R
N
K
Site 35
Y677
K
A
P
E
Y
Y
L
Y
Q
R
N
K
P
V
D
Site 36
Y685
Q
R
N
K
P
V
D
Y
F
V
L
I
L
Q
G
Site 37
S708
E
G
M
K
F
E
A
S
A
F
S
Y
Y
G
V
Site 38
S711
K
F
E
A
S
A
F
S
Y
Y
G
V
M
A
L
Site 39
Y712
F
E
A
S
A
F
S
Y
Y
G
V
M
A
L
T
Site 40
Y713
E
A
S
A
F
S
Y
Y
G
V
M
A
L
T
A
Site 41
S726
T
A
S
P
V
P
L
S
L
S
R
T
F
V
V
Site 42
S728
S
P
V
P
L
S
L
S
R
T
F
V
V
S
R
Site 43
S743
T
E
L
L
A
A
G
S
P
G
E
N
K
S
P
Site 44
S749
G
S
P
G
E
N
K
S
P
P
R
P
C
G
L
Site 45
S759
R
P
C
G
L
N
H
S
D
S
L
S
R
S
D
Site 46
S761
C
G
L
N
H
S
D
S
L
S
R
S
D
R
I
Site 47
S763
L
N
H
S
D
S
L
S
R
S
D
R
I
D
A
Site 48
S765
H
S
D
S
L
S
R
S
D
R
I
D
A
V
T
Site 49
T772
S
D
R
I
D
A
V
T
P
T
L
G
S
S
N
Site 50
T774
R
I
D
A
V
T
P
T
L
G
S
S
N
N
Q
Site 51
S778
V
T
P
T
L
G
S
S
N
N
Q
L
N
S
S
Site 52
S785
S
N
N
Q
L
N
S
S
L
L
Q
V
Y
I
P
Site 53
Y790
N
S
S
L
L
Q
V
Y
I
P
D
Y
S
V
R
Site 54
Y794
L
Q
V
Y
I
P
D
Y
S
V
R
A
L
S
D
Site 55
S795
Q
V
Y
I
P
D
Y
S
V
R
A
L
S
D
L
Site 56
Y812
V
K
I
S
R
Q
Q
Y
Q
N
A
L
M
A
S
Site 57
T824
M
A
S
R
M
D
K
T
P
Q
S
S
D
S
E
Site 58
S827
R
M
D
K
T
P
Q
S
S
D
S
E
N
T
K
Site 59
S828
M
D
K
T
P
Q
S
S
D
S
E
N
T
K
I
Site 60
S830
K
T
P
Q
S
S
D
S
E
N
T
K
I
E
L
Site 61
T840
T
K
I
E
L
T
L
T
E
L
H
D
G
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation