KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF395
Full Name:
Zinc finger protein 395
Alias:
DKFZp434K1210; HDBP2; Papillomavirus regulatory factor PRF- 1; Papillomavirus-binding factor; PBF; PRF-1; ZN395
Type:
Transcription factor
Mass (Da):
54939
Number AA:
513
UniProt ID:
Q9H8N7
International Prot ID:
IPI00386410
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
S
V
L
S
R
R
L
G
K
R
S
Site 2
S13
S
R
R
L
G
K
R
S
L
L
G
A
R
V
L
Site 3
S23
G
A
R
V
L
G
P
S
A
S
E
G
P
S
A
Site 4
S25
R
V
L
G
P
S
A
S
E
G
P
S
A
A
P
Site 5
S29
P
S
A
S
E
G
P
S
A
A
P
P
S
E
P
Site 6
S34
G
P
S
A
A
P
P
S
E
P
L
L
E
G
A
Site 7
T47
G
A
A
P
Q
P
F
T
T
S
D
D
T
P
C
Site 8
S49
A
P
Q
P
F
T
T
S
D
D
T
P
C
Q
E
Site 9
T52
P
F
T
T
S
D
D
T
P
C
Q
E
Q
P
K
Site 10
S66
K
E
V
L
K
A
P
S
T
S
G
L
Q
Q
V
Site 11
Y82
F
Q
P
G
Q
K
V
Y
V
W
Y
G
G
Q
E
Site 12
S98
T
G
L
V
E
Q
H
S
W
M
E
G
Q
V
T
Site 13
Y146
P
G
A
Q
A
L
A
Y
R
P
V
S
R
N
I
Site 14
S150
A
L
A
Y
R
P
V
S
R
N
I
D
V
P
K
Site 15
S160
I
D
V
P
K
R
K
S
D
A
V
E
M
D
E
Site 16
S185
S
C
S
P
V
V
Q
S
P
P
G
T
E
A
N
Site 17
T189
V
V
Q
S
P
P
G
T
E
A
N
F
S
A
S
Site 18
S194
P
G
T
E
A
N
F
S
A
S
R
A
A
C
D
Site 19
S206
A
C
D
P
W
K
E
S
G
D
I
S
D
S
G
Site 20
S210
W
K
E
S
G
D
I
S
D
S
G
S
S
T
T
Site 21
S212
E
S
G
D
I
S
D
S
G
S
S
T
T
S
G
Site 22
S214
G
D
I
S
D
S
G
S
S
T
T
S
G
H
W
Site 23
S215
D
I
S
D
S
G
S
S
T
T
S
G
H
W
S
Site 24
T216
I
S
D
S
G
S
S
T
T
S
G
H
W
S
G
Site 25
S218
D
S
G
S
S
T
T
S
G
H
W
S
G
S
S
Site 26
S222
S
T
T
S
G
H
W
S
G
S
S
G
V
S
T
Site 27
S224
T
S
G
H
W
S
G
S
S
G
V
S
T
P
S
Site 28
S225
S
G
H
W
S
G
S
S
G
V
S
T
P
S
P
Site 29
S228
W
S
G
S
S
G
V
S
T
P
S
P
P
H
P
Site 30
T229
S
G
S
S
G
V
S
T
P
S
P
P
H
P
Q
Site 31
S231
S
S
G
V
S
T
P
S
P
P
H
P
Q
A
S
Site 32
S238
S
P
P
H
P
Q
A
S
P
K
Y
L
G
D
A
Site 33
Y241
H
P
Q
A
S
P
K
Y
L
G
D
A
F
G
S
Site 34
S248
Y
L
G
D
A
F
G
S
P
Q
T
D
H
G
F
Site 35
T251
D
A
F
G
S
P
Q
T
D
H
G
F
E
T
D
Site 36
T257
Q
T
D
H
G
F
E
T
D
P
D
P
F
L
L
Site 37
S275
A
P
R
K
R
K
N
S
V
K
V
M
Y
K
C
Site 38
Y280
K
N
S
V
K
V
M
Y
K
C
L
W
P
N
C
Site 39
S293
N
C
G
K
V
L
R
S
I
V
G
I
K
R
H
Site 40
T309
K
A
L
H
L
G
D
T
V
D
S
D
Q
F
K
Site 41
S312
H
L
G
D
T
V
D
S
D
Q
F
K
R
E
E
Site 42
Y322
F
K
R
E
E
D
F
Y
Y
T
E
V
Q
L
K
Site 43
Y323
K
R
E
E
D
F
Y
Y
T
E
V
Q
L
K
E
Site 44
T348
A
G
T
P
V
P
G
T
P
T
S
E
P
A
P
Site 45
T350
T
P
V
P
G
T
P
T
S
E
P
A
P
T
P
Site 46
S351
P
V
P
G
T
P
T
S
E
P
A
P
T
P
S
Site 47
T356
P
T
S
E
P
A
P
T
P
S
M
T
G
L
P
Site 48
S358
S
E
P
A
P
T
P
S
M
T
G
L
P
L
S
Site 49
S376
P
P
L
H
K
A
Q
S
S
G
P
E
H
P
G
Site 50
S377
P
L
H
K
A
Q
S
S
G
P
E
H
P
G
P
Site 51
S386
P
E
H
P
G
P
E
S
S
L
P
S
G
A
L
Site 52
S387
E
H
P
G
P
E
S
S
L
P
S
G
A
L
S
Site 53
S390
G
P
E
S
S
L
P
S
G
A
L
S
K
S
A
Site 54
S394
S
L
P
S
G
A
L
S
K
S
A
P
G
S
F
Site 55
S396
P
S
G
A
L
S
K
S
A
P
G
S
F
W
H
Site 56
S400
L
S
K
S
A
P
G
S
F
W
H
I
Q
A
D
Site 57
Y410
H
I
Q
A
D
H
A
Y
Q
A
L
P
S
F
Q
Site 58
S415
H
A
Y
Q
A
L
P
S
F
Q
I
P
V
S
P
Site 59
S439
A
A
P
S
A
A
C
S
L
S
P
V
R
S
R
Site 60
S441
P
S
A
A
C
S
L
S
P
V
R
S
R
S
L
Site 61
S445
C
S
L
S
P
V
R
S
R
S
L
S
F
S
E
Site 62
S447
L
S
P
V
R
S
R
S
L
S
F
S
E
P
Q
Site 63
S449
P
V
R
S
R
S
L
S
F
S
E
P
Q
Q
P
Site 64
S451
R
S
R
S
L
S
F
S
E
P
Q
Q
P
A
P
Site 65
S462
Q
P
A
P
A
M
K
S
H
L
I
V
T
S
P
Site 66
S468
K
S
H
L
I
V
T
S
P
P
R
A
Q
S
G
Site 67
S474
T
S
P
P
R
A
Q
S
G
A
R
K
A
R
G
Site 68
Y490
A
K
K
C
R
K
V
Y
G
I
E
H
R
D
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation