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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM45
Full Name:
Tripartite motif-containing protein 45
Alias:
RING finger protein 99
Type:
Mass (Da):
64359
Number AA:
580
UniProt ID:
Q9H8W5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S69
V
D
I
R
G
G
D
S
D
T
S
S
E
G
S
Site 2
T71
I
R
G
G
D
S
D
T
S
S
E
G
S
I
F
Site 3
S72
R
G
G
D
S
D
T
S
S
E
G
S
I
F
Q
Site 4
S73
G
G
D
S
D
T
S
S
E
G
S
I
F
Q
E
Site 5
S76
S
D
T
S
S
E
G
S
I
F
Q
E
L
K
P
Site 6
S85
F
Q
E
L
K
P
R
S
L
Q
S
Q
I
G
I
Site 7
S125
V
N
D
V
M
L
E
S
L
R
G
E
G
Q
G
Site 8
T169
H
R
R
Q
K
K
T
T
Y
H
T
M
V
D
L
Site 9
Y170
R
R
Q
K
K
T
T
Y
H
T
M
V
D
L
K
Site 10
Y182
D
L
K
D
L
K
G
Y
S
R
I
G
K
P
I
Site 11
S237
V
I
H
K
H
G
D
S
V
W
E
L
L
K
G
Site 12
T326
Q
L
L
A
D
M
R
T
G
V
E
F
T
E
H
Site 13
T336
E
F
T
E
H
L
L
T
S
G
S
D
L
E
I
Site 14
Y362
R
K
L
N
K
V
Q
Y
S
T
R
P
G
V
N
Site 15
S363
K
L
N
K
V
Q
Y
S
T
R
P
G
V
N
D
Site 16
Y386
K
A
G
Q
C
R
G
Y
E
I
Y
G
T
I
N
Site 17
Y389
Q
C
R
G
Y
E
I
Y
G
T
I
N
T
K
E
Site 18
T391
R
G
Y
E
I
Y
G
T
I
N
T
K
E
V
D
Site 19
S419
A
R
E
K
Q
T
A
S
F
T
L
L
C
K
D
Site 20
S451
V
P
K
D
K
K
D
S
P
V
R
T
M
V
Q
Site 21
T455
K
K
D
S
P
V
R
T
M
V
Q
D
N
K
D
Site 22
T464
V
Q
D
N
K
D
G
T
Y
Y
I
S
Y
T
P
Site 23
Y465
Q
D
N
K
D
G
T
Y
Y
I
S
Y
T
P
K
Site 24
Y466
D
N
K
D
G
T
Y
Y
I
S
Y
T
P
K
E
Site 25
S468
K
D
G
T
Y
Y
I
S
Y
T
P
K
E
P
G
Site 26
Y469
D
G
T
Y
Y
I
S
Y
T
P
K
E
P
G
V
Site 27
T470
G
T
Y
Y
I
S
Y
T
P
K
E
P
G
V
Y
Site 28
S491
K
E
Q
H
V
Q
G
S
P
F
T
V
M
V
R
Site 29
T494
H
V
Q
G
S
P
F
T
V
M
V
R
R
K
H
Site 30
T521
C
S
S
G
G
Q
K
T
A
R
C
A
C
G
G
Site 31
Y534
G
G
T
M
P
G
G
Y
L
G
C
G
H
G
H
Site 32
S551
H
P
G
H
P
H
W
S
C
C
G
K
F
N
E
Site 33
T565
E
K
S
E
C
T
W
T
G
G
Q
S
A
P
R
Site 34
S569
C
T
W
T
G
G
Q
S
A
P
R
S
L
L
R
Site 35
S573
G
G
Q
S
A
P
R
S
L
L
R
T
V
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation