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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKZF1
Full Name:
Ankyrin repeat and zinc finger domain-containing protein 1
Alias:
Ankyrin repeat and zinc finger domain containing 1; ANKZ1; FLJ10415; Zinc finger protein 744; ZNF744
Type:
Unknown function
Mass (Da):
80927
Number AA:
726
UniProt ID:
Q9H8Y5
International Prot ID:
IPI00335437
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0008270
GO:0043167
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T46
A
L
A
R
A
P
R
T
S
C
S
G
S
G
E
Site 2
S47
L
A
R
A
P
R
T
S
C
S
G
S
G
E
R
Site 3
S49
R
A
P
R
T
S
C
S
G
S
G
E
R
E
S
Site 4
S51
P
R
T
S
C
S
G
S
G
E
R
E
S
P
E
Site 5
S56
S
G
S
G
E
R
E
S
P
E
R
K
L
L
Q
Site 6
S69
L
Q
G
P
M
D
I
S
E
K
L
F
C
S
T
Site 7
S111
L
K
D
K
P
L
L
S
A
L
D
F
E
K
Q
Site 8
S119
A
L
D
F
E
K
Q
S
S
T
G
D
L
S
S
Site 9
S120
L
D
F
E
K
Q
S
S
T
G
D
L
S
S
I
Site 10
T121
D
F
E
K
Q
S
S
T
G
D
L
S
S
I
S
Site 11
S125
Q
S
S
T
G
D
L
S
S
I
S
G
S
E
D
Site 12
S126
S
S
T
G
D
L
S
S
I
S
G
S
E
D
S
Site 13
S128
T
G
D
L
S
S
I
S
G
S
E
D
S
D
S
Site 14
S130
D
L
S
S
I
S
G
S
E
D
S
D
S
A
S
Site 15
S133
S
I
S
G
S
E
D
S
D
S
A
S
E
E
D
Site 16
S135
S
G
S
E
D
S
D
S
A
S
E
E
D
L
Q
Site 17
S137
S
E
D
S
D
S
A
S
E
E
D
L
Q
T
L
Site 18
T143
A
S
E
E
D
L
Q
T
L
D
R
E
R
A
T
Site 19
T150
T
L
D
R
E
R
A
T
F
E
K
L
S
R
P
Site 20
S155
R
A
T
F
E
K
L
S
R
P
P
G
F
Y
P
Site 21
Y161
L
S
R
P
P
G
F
Y
P
H
R
V
L
F
Q
Site 22
Y176
N
A
Q
G
Q
F
L
Y
A
Y
R
C
V
L
G
Site 23
Y178
Q
G
Q
F
L
Y
A
Y
R
C
V
L
G
P
H
Site 24
S201
L
L
L
Q
N
L
Q
S
R
G
P
R
D
C
V
Site 25
T232
R
E
V
V
T
H
K
T
F
H
R
Y
T
V
R
Site 26
T237
H
K
T
F
H
R
Y
T
V
R
A
K
R
G
T
Site 27
T244
T
V
R
A
K
R
G
T
A
Q
G
L
R
D
A
Site 28
S258
A
R
G
G
P
S
H
S
A
G
A
N
L
R
R
Site 29
Y266
A
G
A
N
L
R
R
Y
N
E
A
T
L
Y
K
Site 30
T270
L
R
R
Y
N
E
A
T
L
Y
K
D
V
R
D
Site 31
Y272
R
Y
N
E
A
T
L
Y
K
D
V
R
D
L
L
Site 32
S283
R
D
L
L
A
G
P
S
W
A
K
A
L
E
E
Site 33
T293
K
A
L
E
E
A
G
T
I
L
L
R
A
P
R
Site 34
S304
R
A
P
R
S
G
R
S
L
F
F
G
G
K
G
Site 35
T332
P
L
A
T
R
R
P
T
F
Q
E
L
Q
R
V
Site 36
T345
R
V
L
H
K
L
T
T
L
H
V
Y
E
E
D
Site 37
S361
R
E
A
V
R
L
H
S
P
Q
T
H
W
K
T
Site 38
T364
V
R
L
H
S
P
Q
T
H
W
K
T
V
R
E
Site 39
T368
S
P
Q
T
H
W
K
T
V
R
E
E
R
K
K
Site 40
S398
A
L
G
Q
N
E
E
S
P
K
Q
G
S
G
S
Site 41
S405
S
P
K
Q
G
S
G
S
E
G
E
D
G
F
Q
Site 42
S430
G
T
L
D
L
C
E
S
E
V
L
P
K
R
R
Site 43
S447
K
R
N
K
K
E
K
S
R
D
Q
E
A
G
A
Site 44
S468
Q
T
Q
E
E
E
P
S
T
Q
S
S
Q
A
V
Site 45
T469
T
Q
E
E
E
P
S
T
Q
S
S
Q
A
V
A
Site 46
S472
E
E
P
S
T
Q
S
S
Q
A
V
A
A
P
L
Site 47
S533
L
L
S
A
P
L
G
S
G
G
F
T
L
L
H
Site 48
T537
P
L
G
S
G
G
F
T
L
L
H
A
A
A
A
Site 49
T562
L
E
A
G
A
D
P
T
V
Q
D
S
R
A
R
Site 50
S566
A
D
P
T
V
Q
D
S
R
A
R
P
P
Y
T
Site 51
Y572
D
S
R
A
R
P
P
Y
T
V
A
A
D
K
S
Site 52
T573
S
R
A
R
P
P
Y
T
V
A
A
D
K
S
T
Site 53
S579
Y
T
V
A
A
D
K
S
T
R
N
E
F
R
R
Site 54
T580
T
V
A
A
D
K
S
T
R
N
E
F
R
R
F
Site 55
Y595
M
E
K
N
P
D
A
Y
D
Y
N
K
A
Q
V
Site 56
Y597
K
N
P
D
A
Y
D
Y
N
K
A
Q
V
P
G
Site 57
T607
A
Q
V
P
G
P
L
T
P
E
M
E
A
R
Q
Site 58
T616
E
M
E
A
R
Q
A
T
R
K
R
E
Q
K
A
Site 59
S653
Q
R
R
F
A
A
L
S
D
R
E
K
R
A
L
Site 60
T674
A
A
Q
L
G
A
P
T
S
P
I
P
D
S
A
Site 61
S675
A
Q
L
G
A
P
T
S
P
I
P
D
S
A
I
Site 62
S680
P
T
S
P
I
P
D
S
A
I
V
N
T
R
R
Site 63
S690
V
N
T
R
R
C
W
S
C
G
A
S
L
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation