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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR76
Full Name:
WD repeat-containing protein 76
Alias:
Type:
Mass (Da):
69753
Number AA:
626
UniProt ID:
Q9H967
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
A
A
A
E
K
A
D
S
R
Q
R
P
Q
M
K
Site 2
Y32
K
E
N
Q
N
I
A
Y
V
S
L
R
P
A
Q
Site 3
S34
N
Q
N
I
A
Y
V
S
L
R
P
A
Q
T
T
Site 4
T41
S
L
R
P
A
Q
T
T
V
L
I
K
T
A
K
Site 5
S55
K
V
Y
L
A
P
F
S
L
S
N
Y
Q
L
D
Site 6
Y59
A
P
F
S
L
S
N
Y
Q
L
D
Q
L
M
C
Site 7
S69
D
Q
L
M
C
P
K
S
L
S
E
K
N
S
N
Site 8
S71
L
M
C
P
K
S
L
S
E
K
N
S
N
N
E
Site 9
S75
K
S
L
S
E
K
N
S
N
N
E
V
A
C
K
Site 10
T89
K
K
T
K
I
K
K
T
C
R
R
I
I
P
P
Site 11
S102
P
P
K
M
K
N
T
S
S
K
A
E
S
T
L
Site 12
S103
P
K
M
K
N
T
S
S
K
A
E
S
T
L
Q
Site 13
S107
N
T
S
S
K
A
E
S
T
L
Q
N
S
S
S
Site 14
T108
T
S
S
K
A
E
S
T
L
Q
N
S
S
S
A
Site 15
S114
S
T
L
Q
N
S
S
S
A
V
H
T
E
S
N
Site 16
T118
N
S
S
S
A
V
H
T
E
S
N
K
L
Q
P
Site 17
S120
S
S
A
V
H
T
E
S
N
K
L
Q
P
K
R
Site 18
S135
T
A
D
A
M
N
L
S
V
D
V
E
S
S
Q
Site 19
S141
L
S
V
D
V
E
S
S
Q
D
G
D
S
D
E
Site 20
S146
E
S
S
Q
D
G
D
S
D
E
D
T
T
P
A
Site 21
T150
D
G
D
S
D
E
D
T
T
P
A
L
D
F
S
Site 22
T151
G
D
S
D
E
D
T
T
P
A
L
D
F
S
G
Site 23
S157
T
T
P
A
L
D
F
S
G
L
S
P
Y
E
R
Site 24
S160
A
L
D
F
S
G
L
S
P
Y
E
R
K
R
L
Site 25
Y162
D
F
S
G
L
S
P
Y
E
R
K
R
L
K
N
Site 26
S171
R
K
R
L
K
N
I
S
E
N
A
D
F
F
A
Site 27
S179
E
N
A
D
F
F
A
S
L
Q
L
S
E
S
A
Site 28
S185
A
S
L
Q
L
S
E
S
A
A
R
L
R
E
M
Site 29
S201
E
K
R
Q
P
P
K
S
K
R
K
K
P
K
R
Site 30
S217
N
G
I
G
C
R
R
S
M
R
L
L
K
V
D
Site 31
S229
K
V
D
P
S
G
V
S
L
P
A
A
P
T
P
Site 32
T238
P
A
A
P
T
P
P
T
L
V
A
D
E
T
P
Site 33
T272
R
F
K
G
F
L
H
T
W
A
G
M
S
K
P
Site 34
S277
L
H
T
W
A
G
M
S
K
P
S
S
K
N
T
Site 35
S281
A
G
M
S
K
P
S
S
K
N
T
E
K
G
L
Site 36
T284
S
K
P
S
S
K
N
T
E
K
G
L
S
S
I
Site 37
S289
K
N
T
E
K
G
L
S
S
I
K
S
Y
K
A
Site 38
S293
K
G
L
S
S
I
K
S
Y
K
A
N
L
N
G
Site 39
Y294
G
L
S
S
I
K
S
Y
K
A
N
L
N
G
M
Site 40
T328
L
H
P
S
E
T
R
T
L
V
A
V
G
A
K
Site 41
T345
Q
V
G
L
C
D
L
T
Q
Q
P
K
E
D
G
Site 42
Y354
Q
P
K
E
D
G
V
Y
V
F
H
P
H
S
Q
Site 43
S364
H
P
H
S
Q
P
V
S
C
L
Y
F
S
P
A
Site 44
Y367
S
Q
P
V
S
C
L
Y
F
S
P
A
N
P
A
Site 45
T384
L
S
L
S
Y
D
G
T
L
R
C
G
D
F
S
Site 46
S391
T
L
R
C
G
D
F
S
R
A
I
F
E
E
V
Site 47
Y399
R
A
I
F
E
E
V
Y
R
N
E
R
S
S
F
Site 48
S404
E
V
Y
R
N
E
R
S
S
F
S
S
F
D
F
Site 49
S405
V
Y
R
N
E
R
S
S
F
S
S
F
D
F
L
Site 50
S407
R
N
E
R
S
S
F
S
S
F
D
F
L
A
E
Site 51
S408
N
E
R
S
S
F
S
S
F
D
F
L
A
E
D
Site 52
S429
G
H
W
D
G
N
M
S
L
V
D
R
R
T
P
Site 53
T435
M
S
L
V
D
R
R
T
P
G
T
S
Y
E
K
Site 54
T438
V
D
R
R
T
P
G
T
S
Y
E
K
L
T
S
Site 55
S439
D
R
R
T
P
G
T
S
Y
E
K
L
T
S
S
Site 56
Y440
R
R
T
P
G
T
S
Y
E
K
L
T
S
S
S
Site 57
S445
T
S
Y
E
K
L
T
S
S
S
M
G
K
I
R
Site 58
S446
S
Y
E
K
L
T
S
S
S
M
G
K
I
R
T
Site 59
T453
S
S
M
G
K
I
R
T
V
H
V
H
P
V
H
Site 60
Y463
V
H
P
V
H
R
Q
Y
F
I
T
A
G
L
R
Site 61
T466
V
H
R
Q
Y
F
I
T
A
G
L
R
D
T
H
Site 62
T472
I
T
A
G
L
R
D
T
H
I
Y
D
A
R
R
Site 63
Y475
G
L
R
D
T
H
I
Y
D
A
R
R
L
N
S
Site 64
S482
Y
D
A
R
R
L
N
S
R
R
S
Q
P
L
I
Site 65
S485
R
R
L
N
S
R
R
S
Q
P
L
I
S
L
T
Site 66
S490
R
R
S
Q
P
L
I
S
L
T
E
H
T
K
S
Site 67
T492
S
Q
P
L
I
S
L
T
E
H
T
K
S
I
A
Site 68
T495
L
I
S
L
T
E
H
T
K
S
I
A
S
A
Y
Site 69
S497
S
L
T
E
H
T
K
S
I
A
S
A
Y
F
S
Site 70
S500
E
H
T
K
S
I
A
S
A
Y
F
S
P
L
T
Site 71
Y502
T
K
S
I
A
S
A
Y
F
S
P
L
T
G
N
Site 72
T507
S
A
Y
F
S
P
L
T
G
N
R
V
V
T
T
Site 73
S526
N
L
R
I
F
D
S
S
C
I
S
S
K
I
P
Site 74
T536
S
S
K
I
P
L
L
T
T
I
R
H
N
T
F
Site 75
T537
S
K
I
P
L
L
T
T
I
R
H
N
T
F
T
Site 76
T542
L
T
T
I
R
H
N
T
F
T
G
R
W
L
T
Site 77
T544
T
I
R
H
N
T
F
T
G
R
W
L
T
R
F
Site 78
S586
E
T
G
K
R
V
H
S
F
G
G
E
Y
L
V
Site 79
Y606
N
A
M
H
P
T
R
Y
I
L
A
G
G
N
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation