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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACTR8
Full Name:
Actin-related protein 8
Alias:
ARP8; ARP8 actin-related protein 8; INO80 complex subunit N; INO80N
Type:
Cytoskeletal protein
Mass (Da):
70484
Number AA:
624
UniProt ID:
Q9H981
International Prot ID:
IPI00025646
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
T
Q
A
E
K
G
D
T
E
N
G
K
E
K
G
Site 2
S38
V
P
A
L
V
P
E
S
L
Q
E
Q
I
Q
S
Site 3
T57
V
I
H
P
G
S
T
T
L
R
I
G
R
A
T
Site 4
T66
R
I
G
R
A
T
D
T
L
P
A
S
I
P
H
Site 5
Y87
K
Q
Q
G
Q
P
L
Y
K
D
S
W
L
L
R
Site 6
S102
E
G
L
N
K
P
E
S
N
E
Q
R
Q
N
G
Site 7
S119
M
V
D
Q
A
I
W
S
K
K
M
S
N
G
T
Site 8
S123
A
I
W
S
K
K
M
S
N
G
T
R
R
I
P
Site 9
S132
G
T
R
R
I
P
V
S
P
E
Q
A
R
S
Y
Site 10
S138
V
S
P
E
Q
A
R
S
Y
N
K
Q
M
R
P
Site 11
Y139
S
P
E
Q
A
R
S
Y
N
K
Q
M
R
P
A
Site 12
Y165
N
T
S
H
H
P
E
Y
L
V
G
E
E
A
L
Site 13
Y219
W
S
H
A
I
Q
K
Y
L
E
I
P
L
K
D
Site 14
Y240
I
L
L
I
P
D
I
Y
N
K
Q
H
V
K
E
Site 15
T271
H
Q
E
S
V
C
A
T
Y
G
S
G
L
S
S
Site 16
Y272
Q
E
S
V
C
A
T
Y
G
S
G
L
S
S
T
Site 17
T289
V
D
V
G
D
Q
K
T
S
V
C
C
V
E
D
Site 18
S290
D
V
G
D
Q
K
T
S
V
C
C
V
E
D
G
Site 19
T303
D
G
V
S
H
R
N
T
R
L
C
L
A
Y
G
Site 20
Y309
N
T
R
L
C
L
A
Y
G
G
S
D
V
S
R
Site 21
S315
A
Y
G
G
S
D
V
S
R
C
F
Y
W
L
M
Site 22
Y319
S
D
V
S
R
C
F
Y
W
L
M
Q
R
A
G
Site 23
Y329
M
Q
R
A
G
F
P
Y
R
E
C
Q
L
T
N
Site 24
T349
L
L
Q
H
L
K
E
T
F
C
H
L
D
Q
D
Site 25
S372
F
Q
I
R
H
P
D
S
P
A
L
L
Y
Q
F
Site 26
Y377
P
D
S
P
A
L
L
Y
Q
F
R
L
G
D
E
Site 27
Y394
Q
A
P
M
A
L
F
Y
P
A
T
F
G
I
V
Site 28
T407
I
V
G
Q
K
M
T
T
L
Q
H
R
S
Q
G
Site 29
S412
M
T
T
L
Q
H
R
S
Q
G
D
P
E
D
P
Site 30
Y424
E
D
P
H
D
E
H
Y
L
L
A
T
Q
S
K
Site 31
S430
H
Y
L
L
A
T
Q
S
K
Q
E
Q
S
A
K
Site 32
T439
Q
E
Q
S
A
K
A
T
A
D
R
K
S
A
S
Site 33
S444
K
A
T
A
D
R
K
S
A
S
K
P
I
G
F
Site 34
S446
T
A
D
R
K
S
A
S
K
P
I
G
F
E
G
Site 35
S459
E
G
D
L
R
G
Q
S
S
D
L
P
E
R
L
Site 36
S460
G
D
L
R
G
Q
S
S
D
L
P
E
R
L
H
Site 37
S468
D
L
P
E
R
L
H
S
Q
E
V
D
L
G
S
Site 38
S475
S
Q
E
V
D
L
G
S
A
Q
G
D
G
L
M
Site 39
T492
N
D
S
E
E
A
L
T
A
L
M
S
R
K
T
Site 40
S502
M
S
R
K
T
A
I
S
L
F
E
G
K
A
L
Site 41
S523
L
H
S
I
D
C
C
S
S
D
D
T
K
K
K
Site 42
T527
D
C
C
S
S
D
D
T
K
K
K
M
Y
S
S
Site 43
S534
T
K
K
K
M
Y
S
S
I
L
V
V
G
G
G
Site 44
S562
I
L
N
K
M
P
P
S
F
R
R
I
I
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation