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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYNPO2L
Full Name:
Synaptopodin 2-like protein
Alias:
FLJ12921; synaptopodin 2-like; SYP2L
Type:
Mass (Da):
102462
Number AA:
977
UniProt ID:
Q9H987
International Prot ID:
IPI00016425
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
Q
R
K
P
L
Q
V
S
K
I
R
R
R
S
Q
Site 2
S40
V
S
K
I
R
R
R
S
Q
A
G
R
A
G
L
Site 3
T83
S
G
N
Q
L
V
L
T
V
Q
R
L
A
D
E
Site 4
S95
A
D
E
G
P
V
Q
S
P
S
P
H
E
L
Q
Site 5
S97
E
G
P
V
Q
S
P
S
P
H
E
L
Q
V
L
Site 6
S105
P
H
E
L
Q
V
L
S
P
L
S
P
L
S
P
Site 7
S108
L
Q
V
L
S
P
L
S
P
L
S
P
E
P
P
Site 8
S111
L
S
P
L
S
P
L
S
P
E
P
P
G
A
P
Site 9
S127
P
Q
P
L
Q
P
G
S
L
R
S
P
P
D
S
Site 10
S130
L
Q
P
G
S
L
R
S
P
P
D
S
E
A
Y
Site 11
S134
S
L
R
S
P
P
D
S
E
A
Y
Y
G
E
T
Site 12
Y138
P
P
D
S
E
A
Y
Y
G
E
T
D
S
D
A
Site 13
T141
S
E
A
Y
Y
G
E
T
D
S
D
A
D
G
P
Site 14
S143
A
Y
Y
G
E
T
D
S
D
A
D
G
P
A
T
Site 15
T150
S
D
A
D
G
P
A
T
Q
E
K
P
R
R
P
Site 16
T163
R
P
R
R
R
G
P
T
R
P
T
P
P
G
A
Site 17
T166
R
R
G
P
T
R
P
T
P
P
G
A
P
P
D
Site 18
Y176
G
A
P
P
D
E
V
Y
L
S
D
S
P
A
E
Site 19
S178
P
P
D
E
V
Y
L
S
D
S
P
A
E
P
A
Site 20
S180
D
E
V
Y
L
S
D
S
P
A
E
P
A
P
T
Site 21
T187
S
P
A
E
P
A
P
T
I
P
G
P
P
S
Q
Site 22
S193
P
T
I
P
G
P
P
S
Q
G
D
S
R
V
S
Site 23
S197
G
P
P
S
Q
G
D
S
R
V
S
S
P
S
W
Site 24
S200
S
Q
G
D
S
R
V
S
S
P
S
W
E
D
G
Site 25
S201
Q
G
D
S
R
V
S
S
P
S
W
E
D
G
A
Site 26
S203
D
S
R
V
S
S
P
S
W
E
D
G
A
A
L
Site 27
T247
H
P
V
A
E
D
L
T
T
T
Y
T
Q
K
A
Site 28
T248
P
V
A
E
D
L
T
T
T
Y
T
Q
K
A
K
Site 29
S264
A
K
L
Q
R
A
E
S
L
Q
E
K
S
I
K
Site 30
T275
K
S
I
K
E
A
K
T
K
C
R
T
I
A
S
Site 31
T285
R
T
I
A
S
L
L
T
A
A
P
N
P
H
S
Site 32
S292
T
A
A
P
N
P
H
S
K
G
V
L
M
F
K
Site 33
Y308
R
R
Q
R
A
K
K
Y
T
L
V
S
F
G
A
Site 34
T309
R
Q
R
A
K
K
Y
T
L
V
S
F
G
A
A
Site 35
T330
E
E
D
G
V
P
P
T
S
E
S
E
L
D
E
Site 36
S331
E
D
G
V
P
P
T
S
E
S
E
L
D
E
E
Site 37
S333
G
V
P
P
T
S
E
S
E
L
D
E
E
A
F
Site 38
S341
E
L
D
E
E
A
F
S
D
A
R
S
L
T
N
Site 39
S345
E
A
F
S
D
A
R
S
L
T
N
Q
S
D
W
Site 40
T347
F
S
D
A
R
S
L
T
N
Q
S
D
W
D
S
Site 41
S350
A
R
S
L
T
N
Q
S
D
W
D
S
P
Y
L
Site 42
S354
T
N
Q
S
D
W
D
S
P
Y
L
D
M
E
L
Site 43
Y356
Q
S
D
W
D
S
P
Y
L
D
M
E
L
A
R
Site 44
S366
M
E
L
A
R
A
G
S
R
A
S
E
G
Q
G
Site 45
S369
A
R
A
G
S
R
A
S
E
G
Q
G
S
G
L
Site 46
S374
R
A
S
E
G
Q
G
S
G
L
G
G
Q
L
S
Site 47
S381
S
G
L
G
G
Q
L
S
E
V
S
G
R
G
V
Site 48
S384
G
G
Q
L
S
E
V
S
G
R
G
V
Q
L
F
Site 49
S400
Q
Q
R
Q
R
A
D
S
S
T
Q
E
L
A
R
Site 50
S401
Q
R
Q
R
A
D
S
S
T
Q
E
L
A
R
V
Site 51
T402
R
Q
R
A
D
S
S
T
Q
E
L
A
R
V
E
Site 52
S421
L
N
G
E
G
L
Q
S
P
P
R
A
Q
S
A
Site 53
S427
Q
S
P
P
R
A
Q
S
A
P
P
E
A
A
V
Site 54
S446
P
L
P
A
P
V
A
S
P
R
P
F
Q
P
G
Site 55
T458
Q
P
G
G
G
A
P
T
P
A
P
S
I
F
N
Site 56
S462
G
A
P
T
P
A
P
S
I
F
N
R
S
A
R
Site 57
S467
A
P
S
I
F
N
R
S
A
R
P
F
T
P
G
Site 58
T472
N
R
S
A
R
P
F
T
P
G
L
Q
G
Q
R
Site 59
T481
G
L
Q
G
Q
R
P
T
T
T
S
V
I
F
R
Site 60
T482
L
Q
G
Q
R
P
T
T
T
S
V
I
F
R
P
Site 61
S484
G
Q
R
P
T
T
T
S
V
I
F
R
P
L
A
Site 62
S498
A
P
K
R
A
N
D
S
L
G
G
L
S
P
A
Site 63
S503
N
D
S
L
G
G
L
S
P
A
P
P
P
F
L
Site 64
S511
P
A
P
P
P
F
L
S
S
Q
G
P
T
P
L
Site 65
S512
A
P
P
P
F
L
S
S
Q
G
P
T
P
L
P
Site 66
T516
F
L
S
S
Q
G
P
T
P
L
P
S
F
T
S
Site 67
S520
Q
G
P
T
P
L
P
S
F
T
S
G
V
P
S
Site 68
T522
P
T
P
L
P
S
F
T
S
G
V
P
S
H
A
Site 69
S523
T
P
L
P
S
F
T
S
G
V
P
S
H
A
P
Site 70
S527
S
F
T
S
G
V
P
S
H
A
P
V
S
G
S
Site 71
S532
V
P
S
H
A
P
V
S
G
S
P
S
T
P
R
Site 72
S534
S
H
A
P
V
S
G
S
P
S
T
P
R
S
S
Site 73
S536
A
P
V
S
G
S
P
S
T
P
R
S
S
G
P
Site 74
T537
P
V
S
G
S
P
S
T
P
R
S
S
G
P
V
Site 75
S540
G
S
P
S
T
P
R
S
S
G
P
V
T
A
T
Site 76
S541
S
P
S
T
P
R
S
S
G
P
V
T
A
T
S
Site 77
T545
P
R
S
S
G
P
V
T
A
T
S
S
L
Y
I
Site 78
S556
S
L
Y
I
P
A
P
S
R
P
V
T
P
G
G
Site 79
T560
P
A
P
S
R
P
V
T
P
G
G
A
P
E
P
Site 80
S572
P
E
P
P
A
P
P
S
A
A
A
M
T
S
T
Site 81
S591
L
S
A
P
L
R
P
S
A
R
P
E
A
P
A
Site 82
S608
P
G
A
P
E
P
P
S
A
R
E
Q
R
I
S
Site 83
S615
S
A
R
E
Q
R
I
S
V
P
A
A
R
T
G
Site 84
T632
Q
E
A
R
R
R
G
T
R
K
Q
M
F
R
P
Site 85
T644
F
R
P
G
K
E
E
T
K
N
S
P
N
P
E
Site 86
S647
G
K
E
E
T
K
N
S
P
N
P
E
L
L
S
Site 87
S654
S
P
N
P
E
L
L
S
L
V
Q
N
L
D
E
Site 88
S670
P
R
A
G
G
A
E
S
G
P
E
E
D
A
L
Site 89
S678
G
P
E
E
D
A
L
S
L
G
A
E
A
C
N
Site 90
Y695
Q
P
V
G
A
R
S
Y
K
T
L
P
H
V
T
Site 91
T697
V
G
A
R
S
Y
K
T
L
P
H
V
T
P
K
Site 92
T702
Y
K
T
L
P
H
V
T
P
K
T
P
P
P
M
Site 93
T705
L
P
H
V
T
P
K
T
P
P
P
M
A
P
K
Site 94
T713
P
P
P
M
A
P
K
T
P
P
P
M
T
P
K
Site 95
T718
P
K
T
P
P
P
M
T
P
K
T
P
P
P
V
Site 96
T721
P
P
P
M
T
P
K
T
P
P
P
V
A
P
K
Site 97
S731
P
V
A
P
K
P
P
S
R
G
L
L
D
G
L
Site 98
S767
E
L
F
A
K
R
Q
S
R
A
D
R
Y
V
V
Site 99
Y772
R
Q
S
R
A
D
R
Y
V
V
E
G
T
P
G
Site 100
T777
D
R
Y
V
V
E
G
T
P
G
P
G
L
G
P
Site 101
S788
G
L
G
P
R
P
R
S
P
S
P
T
P
S
L
Site 102
S790
G
P
R
P
R
S
P
S
P
T
P
S
L
P
P
Site 103
T792
R
P
R
S
P
S
P
T
P
S
L
P
P
S
W
Site 104
S794
R
S
P
S
P
T
P
S
L
P
P
S
W
K
Y
Site 105
S798
P
T
P
S
L
P
P
S
W
K
Y
S
P
N
I
Site 106
Y801
S
L
P
P
S
W
K
Y
S
P
N
I
R
A
P
Site 107
S802
L
P
P
S
W
K
Y
S
P
N
I
R
A
P
P
Site 108
S833
R
T
L
P
K
A
Q
S
Q
G
P
R
A
T
P
Site 109
T839
Q
S
Q
G
P
R
A
T
P
K
Q
G
I
K
A
Site 110
T870
C
F
D
E
V
P
P
T
P
G
P
I
A
S
G
Site 111
S876
P
T
P
G
P
I
A
S
G
S
P
K
T
A
R
Site 112
S878
P
G
P
I
A
S
G
S
P
K
T
A
R
V
Q
Site 113
T881
I
A
S
G
S
P
K
T
A
R
V
Q
E
I
R
Site 114
S891
V
Q
E
I
R
R
F
S
T
P
A
P
Q
P
T
Site 115
T892
Q
E
I
R
R
F
S
T
P
A
P
Q
P
T
A
Site 116
T898
S
T
P
A
P
Q
P
T
A
E
P
L
A
P
T
Site 117
T905
T
A
E
P
L
A
P
T
V
L
A
P
R
A
A
Site 118
T913
V
L
A
P
R
A
A
T
T
L
D
E
P
I
W
Site 119
S926
I
W
R
T
E
L
A
S
A
P
V
P
S
P
A
Site 120
S931
L
A
S
A
P
V
P
S
P
A
P
P
P
E
A
Site 121
S945
A
P
R
G
L
G
A
S
P
S
S
C
G
F
Q
Site 122
S959
Q
V
A
R
P
R
F
S
A
T
R
T
G
L
Q
Site 123
T963
P
R
F
S
A
T
R
T
G
L
Q
A
H
V
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation