KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ACTR5
Full Name:
Actin-related protein 5
Alias:
Sarcoma antigen NY-SAR-16
Type:
Mass (Da):
68297
Number AA:
607
UniProt ID:
Q9H9F9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S76
R
G
G
A
R
G
A
S
G
P
Q
V
G
N
A
Site 2
S86
Q
V
G
N
A
L
G
S
L
E
P
L
R
W
M
Site 3
S96
P
L
R
W
M
L
R
S
P
F
D
R
N
V
P
Site 4
Y115
L
Q
E
L
L
L
D
Y
S
F
Q
H
L
G
V
Site 5
S116
Q
E
L
L
L
D
Y
S
F
Q
H
L
G
V
S
Site 6
S123
S
F
Q
H
L
G
V
S
S
Q
G
C
V
D
H
Site 7
S124
F
Q
H
L
G
V
S
S
Q
G
C
V
D
H
P
Site 8
Y143
E
A
V
C
N
P
L
Y
S
R
Q
M
M
S
E
Site 9
S170
Y
G
I
D
S
L
F
S
F
Y
H
N
K
P
K
Site 10
S182
K
P
K
N
S
M
C
S
G
L
I
I
S
S
G
Site 11
S188
C
S
G
L
I
I
S
S
G
Y
Q
C
T
H
V
Site 12
S216
K
R
I
N
L
G
G
S
Q
A
A
G
Y
L
Q
Site 13
Y221
G
G
S
Q
A
A
G
Y
L
Q
R
L
L
Q
L
Site 14
Y256
H
S
Y
I
A
E
D
Y
V
E
E
L
H
K
W
Site 15
S281
H
K
M
Q
L
P
F
S
S
K
L
L
G
S
T
Site 16
S287
F
S
S
K
L
L
G
S
T
L
T
S
E
E
K
Site 17
S291
L
L
G
S
T
L
T
S
E
E
K
Q
E
R
R
Site 18
Y329
E
R
L
D
R
L
L
Y
V
Q
E
L
L
E
D
Site 19
S353
L
I
E
L
N
M
D
S
P
E
E
L
Q
S
Y
Site 20
S359
D
S
P
E
E
L
Q
S
Y
I
Q
K
L
S
I
Site 21
Y360
S
P
E
E
L
Q
S
Y
I
Q
K
L
S
I
A
Site 22
S365
Q
S
Y
I
Q
K
L
S
I
A
V
E
Q
A
K
Site 23
S389
L
E
V
D
V
V
D
S
K
P
E
T
P
D
L
Site 24
T393
V
V
D
S
K
P
E
T
P
D
L
E
Q
L
E
Site 25
S402
D
L
E
Q
L
E
P
S
L
E
D
V
E
S
M
Site 26
S408
P
S
L
E
D
V
E
S
M
N
D
F
D
P
L
Site 27
T420
D
P
L
F
S
E
E
T
P
G
V
E
K
P
V
Site 28
T428
P
G
V
E
K
P
V
T
T
V
Q
P
V
F
N
Site 29
S459
P
E
I
I
F
Q
P
S
L
I
G
E
E
Q
A
Site 30
Y474
G
I
A
E
T
L
Q
Y
I
L
D
R
Y
P
K
Site 31
Y479
L
Q
Y
I
L
D
R
Y
P
K
D
I
Q
E
M
Site 32
T498
V
F
L
T
G
G
N
T
M
Y
P
G
M
K
A
Site 33
Y500
L
T
G
G
N
T
M
Y
P
G
M
K
A
R
M
Site 34
S520
E
M
R
P
F
R
S
S
F
Q
V
Q
L
A
S
Site 35
Y535
N
P
V
L
D
A
W
Y
G
A
R
D
W
A
L
Site 36
T553
D
D
N
E
V
W
I
T
R
K
E
Y
E
E
K
Site 37
Y557
V
W
I
T
R
K
E
Y
E
E
K
G
G
E
Y
Site 38
Y574
E
H
C
A
S
N
I
Y
V
P
I
R
L
P
K
Site 39
S584
I
R
L
P
K
Q
A
S
R
S
S
D
A
Q
A
Site 40
S586
L
P
K
Q
A
S
R
S
S
D
A
Q
A
S
S
Site 41
S587
P
K
Q
A
S
R
S
S
D
A
Q
A
S
S
K
Site 42
S592
R
S
S
D
A
Q
A
S
S
K
G
S
A
A
G
Site 43
S593
S
S
D
A
Q
A
S
S
K
G
S
A
A
G
G
Site 44
S596
A
Q
A
S
S
K
G
S
A
A
G
G
G
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation