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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPF1
Full Name:
Ribosome production factor 1
Alias:
Brix domain-containing protein 5;Ribosome biogenesis protein RPF1
Type:
Mass (Da):
40111
Number AA:
349
UniProt ID:
Q9H9Y2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
K
A
G
D
K
S
S
S
S
G
K
K
S
Site 2
S9
A
K
A
G
D
K
S
S
S
S
G
K
K
S
L
Site 3
S10
K
A
G
D
K
S
S
S
S
G
K
K
S
L
K
Site 4
S11
A
G
D
K
S
S
S
S
G
K
K
S
L
K
R
Site 5
S15
S
S
S
S
G
K
K
S
L
K
R
K
A
A
A
Site 6
T36
A
G
A
G
D
G
A
T
E
N
G
V
Q
P
P
Site 7
S55
F
P
P
G
F
S
I
S
E
I
K
N
K
Q
R
Site 8
T68
Q
R
R
H
L
M
F
T
R
W
K
Q
Q
Q
R
Site 9
T104
P
P
K
P
V
P
K
T
I
D
N
Q
R
V
Y
Site 10
Y111
T
I
D
N
Q
R
V
Y
D
E
T
T
V
D
P
Site 11
T114
N
Q
R
V
Y
D
E
T
T
V
D
P
N
D
E
Site 12
T115
Q
R
V
Y
D
E
T
T
V
D
P
N
D
E
E
Site 13
Y125
P
N
D
E
E
V
A
Y
D
E
A
T
D
E
F
Site 14
T129
E
V
A
Y
D
E
A
T
D
E
F
A
S
Y
F
Site 15
Y135
A
T
D
E
F
A
S
Y
F
N
K
Q
T
S
P
Site 16
S141
S
Y
F
N
K
Q
T
S
P
K
I
L
I
T
T
Site 17
T147
T
S
P
K
I
L
I
T
T
S
D
R
P
H
G
Site 18
S149
P
K
I
L
I
T
T
S
D
R
P
H
G
R
T
Site 19
T156
S
D
R
P
H
G
R
T
V
R
L
C
E
Q
L
Site 20
S164
V
R
L
C
E
Q
L
S
T
V
I
P
N
S
H
Site 21
T165
R
L
C
E
Q
L
S
T
V
I
P
N
S
H
V
Site 22
S170
L
S
T
V
I
P
N
S
H
V
Y
Y
R
R
G
Site 23
Y173
V
I
P
N
S
H
V
Y
Y
R
R
G
L
A
L
Site 24
Y174
I
P
N
S
H
V
Y
Y
R
R
G
L
A
L
K
Site 25
T204
V
I
N
E
D
R
K
T
P
N
G
L
I
L
S
Site 26
S211
T
P
N
G
L
I
L
S
H
L
P
N
G
P
T
Site 27
T218
S
H
L
P
N
G
P
T
A
H
F
K
M
S
S
Site 28
S224
P
T
A
H
F
K
M
S
S
V
R
L
R
K
E
Site 29
S225
T
A
H
F
K
M
S
S
V
R
L
R
K
E
I
Site 30
T240
K
R
R
G
K
D
P
T
E
H
I
P
E
I
I
Site 31
S265
S
I
G
R
M
F
A
S
L
F
P
H
N
P
Q
Site 32
Y287
T
F
H
N
Q
R
D
Y
I
F
F
R
F
H
R
Site 33
Y295
I
F
F
R
F
H
R
Y
I
F
R
S
E
K
K
Site 34
T313
Q
E
L
G
P
R
F
T
L
K
L
R
S
L
Q
Site 35
S318
R
F
T
L
K
L
R
S
L
Q
K
G
T
F
D
Site 36
T323
L
R
S
L
Q
K
G
T
F
D
S
K
Y
G
E
Site 37
Y328
K
G
T
F
D
S
K
Y
G
E
Y
E
W
V
H
Site 38
T342
H
K
P
R
E
M
D
T
S
R
R
K
F
H
L
Site 39
S343
K
P
R
E
M
D
T
S
R
R
K
F
H
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation