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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBC1D17
Full Name:
TBC1 domain family member 17
Alias:
Type:
Mass (Da):
72636
Number AA:
648
UniProt ID:
Q9HA65
International Prot ID:
IPI00002957
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005083
GO:0005096
GO:0005097
PhosphoSite+
KinaseNET
Biological Process:
GO:0032313
GO:0032318
GO:0043087
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
V
F
E
K
G
G
V
Y
L
H
T
S
A
K
K
Site 2
T19
K
G
G
V
Y
L
H
T
S
A
K
K
Y
Q
D
Site 3
S20
G
G
V
Y
L
H
T
S
A
K
K
Y
Q
D
R
Site 4
Y24
L
H
T
S
A
K
K
Y
Q
D
R
D
S
L
I
Site 5
S29
K
K
Y
Q
D
R
D
S
L
I
A
G
V
I
R
Site 6
S57
P
V
E
E
A
G
D
S
T
Q
I
L
F
S
K
Site 7
T58
V
E
E
A
G
D
S
T
Q
I
L
F
S
K
K
Site 8
S63
D
S
T
Q
I
L
F
S
K
K
D
S
S
G
G
Site 9
S67
I
L
F
S
K
K
D
S
S
G
G
D
S
C
A
Site 10
S68
L
F
S
K
K
D
S
S
G
G
D
S
C
A
S
Site 11
S72
K
D
S
S
G
G
D
S
C
A
S
E
E
E
P
Site 12
S75
S
G
G
D
S
C
A
S
E
E
E
P
T
F
D
Site 13
T80
C
A
S
E
E
E
P
T
F
D
P
G
Y
E
P
Site 14
Y85
E
P
T
F
D
P
G
Y
E
P
D
W
A
V
I
Site 15
S93
E
P
D
W
A
V
I
S
T
V
R
P
Q
P
C
Site 16
T94
P
D
W
A
V
I
S
T
V
R
P
Q
P
C
H
Site 17
S102
V
R
P
Q
P
C
H
S
E
P
T
R
G
A
E
Site 18
S111
P
T
R
G
A
E
P
S
C
P
Q
G
S
W
A
Site 19
S116
E
P
S
C
P
Q
G
S
W
A
F
S
V
S
L
Site 20
S120
P
Q
G
S
W
A
F
S
V
S
L
G
E
L
K
Site 21
S128
V
S
L
G
E
L
K
S
I
R
R
S
K
P
G
Site 22
S132
E
L
K
S
I
R
R
S
K
P
G
L
S
W
A
Site 23
S176
S
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Site 24
S177
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Y
Site 25
S181
L
A
S
S
P
Q
D
S
R
L
Y
L
V
F
P
Site 26
Y184
S
P
Q
D
S
R
L
Y
L
V
F
P
H
D
S
Site 27
S191
Y
L
V
F
P
H
D
S
S
A
L
S
N
S
F
Site 28
S192
L
V
F
P
H
D
S
S
A
L
S
N
S
F
H
Site 29
S195
P
H
D
S
S
A
L
S
N
S
F
H
H
L
Q
Site 30
S197
D
S
S
A
L
S
N
S
F
H
H
L
Q
L
F
Site 31
S208
L
Q
L
F
D
Q
D
S
S
N
V
V
S
R
F
Site 32
S209
Q
L
F
D
Q
D
S
S
N
V
V
S
R
F
L
Site 33
S213
Q
D
S
S
N
V
V
S
R
F
L
Q
D
P
Y
Site 34
Y220
S
R
F
L
Q
D
P
Y
S
T
T
F
S
S
F
Site 35
S221
R
F
L
Q
D
P
Y
S
T
T
F
S
S
F
S
Site 36
T222
F
L
Q
D
P
Y
S
T
T
F
S
S
F
S
R
Site 37
T223
L
Q
D
P
Y
S
T
T
F
S
S
F
S
R
V
Site 38
S225
D
P
Y
S
T
T
F
S
S
F
S
R
V
T
N
Site 39
S226
P
Y
S
T
T
F
S
S
F
S
R
V
T
N
F
Site 40
S247
P
Q
P
E
G
A
A
S
D
L
P
P
P
P
D
Site 41
T274
V
E
L
G
P
R
P
T
V
E
R
G
P
P
V
Site 42
T282
V
E
R
G
P
P
V
T
E
E
E
W
A
R
H
Site 43
S308
E
L
K
N
R
I
F
S
G
G
L
S
P
S
L
Site 44
S312
R
I
F
S
G
G
L
S
P
S
L
R
R
E
A
Site 45
S314
F
S
G
G
L
S
P
S
L
R
R
E
A
W
K
Site 46
S328
K
F
L
L
G
Y
L
S
W
E
G
T
A
E
E
Site 47
T332
G
Y
L
S
W
E
G
T
A
E
E
H
K
A
H
Site 48
T344
K
A
H
I
R
K
K
T
D
E
Y
F
R
M
K
Site 49
Y347
I
R
K
K
T
D
E
Y
F
R
M
K
L
Q
W
Site 50
S356
R
M
K
L
Q
W
K
S
V
S
P
E
Q
E
R
Site 51
S358
K
L
Q
W
K
S
V
S
P
E
Q
E
R
R
N
Site 52
S366
P
E
Q
E
R
R
N
S
L
L
H
G
Y
R
S
Site 53
S373
S
L
L
H
G
Y
R
S
L
I
E
R
D
V
S
Site 54
S380
S
L
I
E
R
D
V
S
R
T
D
R
T
N
K
Site 55
T382
I
E
R
D
V
S
R
T
D
R
T
N
K
F
Y
Site 56
T385
D
V
S
R
T
D
R
T
N
K
F
Y
E
G
P
Site 57
Y389
T
D
R
T
N
K
F
Y
E
G
P
E
N
P
G
Site 58
Y416
M
Y
H
F
D
L
G
Y
V
Q
G
M
S
D
L
Site 59
T458
N
F
E
E
S
Q
E
T
M
K
R
Q
L
G
R
Site 60
S544
E
R
D
T
L
M
L
S
G
F
G
S
N
E
I
Site 61
T559
L
K
H
I
N
E
L
T
M
K
L
S
V
E
D
Site 62
S563
N
E
L
T
M
K
L
S
V
E
D
V
L
T
R
Site 63
T569
L
S
V
E
D
V
L
T
R
A
E
A
L
H
R
Site 64
T579
E
A
L
H
R
Q
L
T
A
C
P
E
L
P
H
Site 65
S602
A
P
P
A
E
P
H
S
P
S
P
T
A
S
P
Site 66
S604
P
A
E
P
H
S
P
S
P
T
A
S
P
L
P
Site 67
T606
E
P
H
S
P
S
P
T
A
S
P
L
P
L
S
Site 68
S608
H
S
P
S
P
T
A
S
P
L
P
L
S
P
T
Site 69
S613
T
A
S
P
L
P
L
S
P
T
R
A
P
P
T
Site 70
T615
S
P
L
P
L
S
P
T
R
A
P
P
T
P
P
Site 71
T620
S
P
T
R
A
P
P
T
P
P
P
S
T
D
T
Site 72
S624
A
P
P
T
P
P
P
S
T
D
T
A
P
Q
P
Site 73
T625
P
P
T
P
P
P
S
T
D
T
A
P
Q
P
D
Site 74
S633
D
T
A
P
Q
P
D
S
S
L
E
I
L
P
E
Site 75
S634
T
A
P
Q
P
D
S
S
L
E
I
L
P
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation