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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UGT1A10
Full Name:
UDP-glucuronosyltransferase 1-10
Alias:
GNT1; UD110; UD17C; UDP glucuronosyltransferase 1 family, polypeptide A10; UDP-glucuronosyltransferase 1-10 precursor, microsomal; UDPGT; UGT1; UGT1*10; UGT1.10; UGT1-10; UGT1J; UGT-1J
Type:
EC 2.4.1.17; Lipid Metabolism - androgen and estrogen; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Transferase; Carbohydrate Metabolism - starch and sucrose; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; Carbohydrate Metabolism - pentose and glucuronate interconversions; Carbohydrate Metabolism - ascorbate and aldarate; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - metabolism by cytochrome P450
Mass (Da):
59810
Number AA:
530
UniProt ID:
Q9HAW8
International Prot ID:
IPI00233885
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
GO:0005792
Uniprot
OncoNet
Molecular Function:
GO:0015020
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S69
V
S
W
Q
L
E
R
S
L
N
C
T
V
K
T
Site 2
T73
L
E
R
S
L
N
C
T
V
K
T
Y
S
T
S
Site 3
T76
S
L
N
C
T
V
K
T
Y
S
T
S
Y
T
L
Site 4
Y77
L
N
C
T
V
K
T
Y
S
T
S
Y
T
L
E
Site 5
S78
N
C
T
V
K
T
Y
S
T
S
Y
T
L
E
D
Site 6
T82
K
T
Y
S
T
S
Y
T
L
E
D
Q
N
R
E
Site 7
S104
Q
W
K
A
Q
A
Q
S
I
F
S
L
L
M
S
Site 8
S126
L
F
F
S
H
C
R
S
L
F
N
D
R
K
L
Site 9
Y136
N
D
R
K
L
V
E
Y
L
K
E
S
S
F
D
Site 10
S198
P
N
D
L
L
G
F
S
D
A
M
T
F
K
E
Site 11
Y222
E
D
H
L
F
C
Q
Y
L
F
R
N
A
L
E
Site 12
T240
E
I
L
Q
T
P
V
T
A
Y
D
L
Y
S
H
Site 13
Y242
L
Q
T
P
V
T
A
Y
D
L
Y
S
H
T
S
Site 14
Y261
R
T
D
F
V
L
D
Y
P
K
P
V
M
P
N
Site 15
Y290
L
P
M
E
F
E
A
Y
I
N
A
S
G
E
H
Site 16
S309
F
S
L
G
S
M
V
S
E
I
P
E
K
K
A
Site 17
T329
A
L
G
K
I
P
Q
T
V
L
W
R
Y
T
G
Site 18
Y334
P
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
Site 19
T335
Q
T
V
L
W
R
Y
T
G
T
R
P
S
N
L
Site 20
S340
R
Y
T
G
T
R
P
S
N
L
A
N
N
T
I
Site 21
Y376
H
A
G
S
H
G
V
Y
E
S
I
C
N
G
V
Site 22
T403
D
N
A
K
R
M
E
T
K
G
A
G
V
T
L
Site 23
S432
K
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
Site 24
Y433
A
V
I
N
D
K
S
Y
K
E
N
I
M
R
L
Site 25
S441
K
E
N
I
M
R
L
S
S
L
H
K
D
R
P
Site 26
S442
E
N
I
M
R
L
S
S
L
H
K
D
R
P
V
Site 27
Y481
A
A
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
Site 28
Y483
H
D
L
T
W
Y
Q
Y
H
S
L
D
V
I
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation