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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SP110
Full Name:
Sp110 nuclear body protein
Alias:
Transcriptional coactivator Sp110
Type:
Mass (Da):
78477
Number AA:
689
UniProt ID:
Q9HB58
International Prot ID:
IPI00162549
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S41
F
E
G
L
L
D
N
S
I
I
T
K
R
M
Y
Site 2
Y48
S
I
I
T
K
R
M
Y
M
E
S
L
E
A
C
Site 3
S51
T
K
R
M
Y
M
E
S
L
E
A
C
R
N
L
Site 4
Y93
S
Q
I
N
L
R
E
Y
P
N
L
V
T
I
Y
Site 5
T98
R
E
Y
P
N
L
V
T
I
Y
R
S
F
K
R
Site 6
S102
N
L
V
T
I
Y
R
S
F
K
R
V
G
A
S
Site 7
S109
S
F
K
R
V
G
A
S
Y
E
W
Q
S
R
D
Site 8
Y110
F
K
R
V
G
A
S
Y
E
W
Q
S
R
D
T
Site 9
T117
Y
E
W
Q
S
R
D
T
P
I
L
L
E
A
P
Site 10
T135
A
E
G
S
S
L
H
T
P
L
A
L
P
P
P
Site 11
S148
P
P
Q
P
P
Q
P
S
C
S
P
C
A
P
R
Site 12
S150
Q
P
P
Q
P
S
C
S
P
C
A
P
R
V
S
Site 13
S157
S
P
C
A
P
R
V
S
E
P
G
T
S
S
Q
Site 14
T161
P
R
V
S
E
P
G
T
S
S
Q
Q
S
D
E
Site 15
S162
R
V
S
E
P
G
T
S
S
Q
Q
S
D
E
I
Site 16
S163
V
S
E
P
G
T
S
S
Q
Q
S
D
E
I
L
Site 17
S166
P
G
T
S
S
Q
Q
S
D
E
I
L
S
E
S
Site 18
S171
Q
Q
S
D
E
I
L
S
E
S
P
S
P
S
D
Site 19
S173
S
D
E
I
L
S
E
S
P
S
P
S
D
P
V
Site 20
S175
E
I
L
S
E
S
P
S
P
S
D
P
V
L
P
Site 21
S177
L
S
E
S
P
S
P
S
D
P
V
L
P
L
P
Site 22
T193
L
I
Q
E
G
R
S
T
S
V
T
N
D
K
L
Site 23
S194
I
Q
E
G
R
S
T
S
V
T
N
D
K
L
T
Site 24
T196
E
G
R
S
T
S
V
T
N
D
K
L
T
S
K
Site 25
S210
K
M
N
A
E
E
D
S
E
E
M
P
S
L
L
Site 26
S215
E
D
S
E
E
M
P
S
L
L
T
S
T
V
Q
Site 27
S225
T
S
T
V
Q
V
A
S
D
N
L
I
P
Q
I
Site 28
S244
D
P
Q
E
M
P
H
S
P
L
G
S
M
P
E
Site 29
S248
M
P
H
S
P
L
G
S
M
P
E
I
R
D
N
Site 30
S256
M
P
E
I
R
D
N
S
P
E
P
N
D
P
E
Site 31
S269
P
E
E
P
Q
E
V
S
S
T
P
S
D
K
K
Site 32
S270
E
E
P
Q
E
V
S
S
T
P
S
D
K
K
G
Site 33
T271
E
P
Q
E
V
S
S
T
P
S
D
K
K
G
K
Site 34
S273
Q
E
V
S
S
T
P
S
D
K
K
G
K
K
R
Site 35
S286
K
R
K
R
C
I
W
S
T
P
K
R
R
H
K
Site 36
T287
R
K
R
C
I
W
S
T
P
K
R
R
H
K
K
Site 37
S296
K
R
R
H
K
K
K
S
L
P
R
G
T
A
S
Site 38
T301
K
K
S
L
P
R
G
T
A
S
S
R
H
G
I
Site 39
S303
S
L
P
R
G
T
A
S
S
R
H
G
I
Q
K
Site 40
S304
L
P
R
G
T
A
S
S
R
H
G
I
Q
K
K
Site 41
S325
V
P
Q
K
K
D
D
S
T
C
N
S
T
V
E
Site 42
T326
P
Q
K
K
D
D
S
T
C
N
S
T
V
E
T
Site 43
S329
K
D
D
S
T
C
N
S
T
V
E
T
R
A
Q
Site 44
S346
R
T
E
C
A
R
K
S
R
S
E
E
I
I
D
Site 45
S348
E
C
A
R
K
S
R
S
E
E
I
I
D
G
T
Site 46
T355
S
E
E
I
I
D
G
T
S
E
M
N
E
G
K
Site 47
S356
E
E
I
I
D
G
T
S
E
M
N
E
G
K
R
Site 48
S364
E
M
N
E
G
K
R
S
Q
K
T
P
S
T
P
Site 49
T367
E
G
K
R
S
Q
K
T
P
S
T
P
R
R
V
Site 50
S369
K
R
S
Q
K
T
P
S
T
P
R
R
V
T
Q
Site 51
T370
R
S
Q
K
T
P
S
T
P
R
R
V
T
Q
G
Site 52
T375
P
S
T
P
R
R
V
T
Q
G
A
A
S
P
G
Site 53
S380
R
V
T
Q
G
A
A
S
P
G
H
G
I
Q
E
Site 54
T396
L
Q
V
V
D
K
V
T
Q
R
K
D
D
S
T
Site 55
S402
V
T
Q
R
K
D
D
S
T
W
N
S
E
V
M
Site 56
T403
T
Q
R
K
D
D
S
T
W
N
S
E
V
M
M
Site 57
S423
R
T
K
C
A
R
K
S
R
L
K
E
K
K
K
Site 58
S436
K
K
E
K
D
I
C
S
S
S
K
R
R
F
Q
Site 59
S437
K
E
K
D
I
C
S
S
S
K
R
R
F
Q
K
Site 60
S438
E
K
D
I
C
S
S
S
K
R
R
F
Q
K
N
Site 61
S454
H
R
R
G
K
P
K
S
D
T
V
D
F
H
C
Site 62
T456
R
G
K
P
K
S
D
T
V
D
F
H
C
S
K
Site 63
Y476
G
E
A
K
G
I
L
Y
K
K
K
M
K
H
G
Site 64
S484
K
K
K
M
K
H
G
S
S
V
K
C
I
R
N
Site 65
S485
K
K
M
K
H
G
S
S
V
K
C
I
R
N
E
Site 66
T498
N
E
D
G
T
W
L
T
P
N
E
F
E
V
E
Site 67
T524
N
I
R
C
E
G
M
T
L
G
E
L
L
K
R
Site 68
S534
E
L
L
K
R
K
N
S
D
E
C
E
V
C
C
Site 69
S585
R
M
K
R
S
S
G
S
Q
Q
C
H
H
V
S
Site 70
T594
Q
C
H
H
V
S
K
T
L
E
R
Q
M
Q
P
Site 71
Y609
Q
D
Q
L
I
R
D
Y
G
E
P
F
Q
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation