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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IFT122
Full Name:
Intraflagellar transport protein 122 homolog
Alias:
WD repeat-containing protein 10;WD repeat-containing protein 140
Type:
Mass (Da):
141825
Number AA:
1241
UniProt ID:
Q9HBG6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
A
G
S
R
L
L
V
Y
D
T
S
D
G
T
L
Site 2
T40
S
R
L
L
V
Y
D
T
S
D
G
T
L
L
Q
Site 3
S41
R
L
L
V
Y
D
T
S
D
G
T
L
L
Q
P
Site 4
T44
V
Y
D
T
S
D
G
T
L
L
Q
P
L
K
G
Site 5
T55
P
L
K
G
H
K
D
T
V
Y
C
V
A
Y
A
Site 6
Y57
K
G
H
K
D
T
V
Y
C
V
A
Y
A
K
D
Site 7
Y61
D
T
V
Y
C
V
A
Y
A
K
D
G
K
R
F
Site 8
S70
K
D
G
K
R
F
A
S
G
S
A
D
K
S
V
Site 9
S72
G
K
R
F
A
S
G
S
A
D
K
S
V
I
I
Site 10
S76
A
S
G
S
A
D
K
S
V
I
I
W
T
S
K
Site 11
S110
P
I
T
H
Q
L
A
S
C
S
S
S
D
F
G
Site 12
S112
T
H
Q
L
A
S
C
S
S
S
D
F
G
L
W
Site 13
S113
H
Q
L
A
S
C
S
S
S
D
F
G
L
W
S
Site 14
S114
Q
L
A
S
C
S
S
S
D
F
G
L
W
S
P
Site 15
S120
S
S
D
F
G
L
W
S
P
E
Q
K
S
V
S
Site 16
S125
L
W
S
P
E
Q
K
S
V
S
K
H
K
S
S
Site 17
S127
S
P
E
Q
K
S
V
S
K
H
K
S
S
S
K
Site 18
S131
K
S
V
S
K
H
K
S
S
S
K
I
I
C
C
Site 19
Y146
S
W
T
N
D
G
Q
Y
L
A
L
G
M
F
N
Site 20
S175
K
I
E
R
P
G
G
S
L
S
P
I
W
S
I
Site 21
S177
E
R
P
G
G
S
L
S
P
I
W
S
I
C
W
Site 22
S181
G
S
L
S
P
I
W
S
I
C
W
N
P
S
S
Site 23
S187
W
S
I
C
W
N
P
S
S
R
W
E
S
F
W
Site 24
S192
N
P
S
S
R
W
E
S
F
W
M
N
R
E
N
Site 25
Y210
E
D
V
I
V
N
R
Y
I
Q
E
I
P
S
T
Site 26
S216
R
Y
I
Q
E
I
P
S
T
L
K
S
A
V
Y
Site 27
T217
Y
I
Q
E
I
P
S
T
L
K
S
A
V
Y
S
Site 28
S220
E
I
P
S
T
L
K
S
A
V
Y
S
S
Q
G
Site 29
Y223
S
T
L
K
S
A
V
Y
S
S
Q
G
S
E
A
Site 30
S224
T
L
K
S
A
V
Y
S
S
Q
G
S
E
A
E
Site 31
S228
A
V
Y
S
S
Q
G
S
E
A
E
E
E
E
P
Site 32
S241
E
P
E
E
E
D
D
S
P
R
D
D
N
L
E
Site 33
S264
A
D
W
G
Q
K
V
S
F
Y
Q
L
S
G
K
Site 34
Y266
W
G
Q
K
V
S
F
Y
Q
L
S
G
K
Q
I
Site 35
Y294
S
Y
F
T
K
G
E
Y
I
L
L
G
G
S
D
Site 36
S305
G
G
S
D
K
Q
V
S
L
F
T
K
D
G
V
Site 37
T316
K
D
G
V
R
L
G
T
V
G
E
Q
N
S
W
Site 38
Y335
Q
A
K
P
D
S
N
Y
V
V
V
G
C
Q
D
Site 39
Y359
F
S
T
V
H
G
L
Y
K
D
R
Y
A
Y
R
Site 40
Y363
H
G
L
Y
K
D
R
Y
A
Y
R
D
S
M
T
Site 41
Y365
L
Y
K
D
R
Y
A
Y
R
D
S
M
T
D
V
Site 42
S368
D
R
Y
A
Y
R
D
S
M
T
D
V
I
V
Q
Site 43
T370
Y
A
Y
R
D
S
M
T
D
V
I
V
Q
H
L
Site 44
Y412
L
P
E
K
I
L
I
Y
E
L
Y
S
E
D
L
Site 45
Y415
K
I
L
I
Y
E
L
Y
S
E
D
L
S
D
M
Site 46
S416
I
L
I
Y
E
L
Y
S
E
D
L
S
D
M
H
Site 47
S420
E
L
Y
S
E
D
L
S
D
M
H
Y
R
V
K
Site 48
Y424
E
D
L
S
D
M
H
Y
R
V
K
E
K
I
I
Site 49
S458
E
K
R
L
Q
C
L
S
F
S
G
V
K
E
R
Site 50
S523
A
V
R
C
L
D
M
S
A
S
R
K
K
L
A
Site 51
S525
R
C
L
D
M
S
A
S
R
K
K
L
A
V
V
Site 52
Y541
E
N
D
T
C
L
V
Y
D
I
D
T
K
E
L
Site 53
S581
G
Y
L
N
I
K
A
S
T
F
P
V
H
R
Q
Site 54
T582
Y
L
N
I
K
A
S
T
F
P
V
H
R
Q
K
Site 55
S618
S
A
V
E
V
P
Q
S
A
P
M
Y
Q
Y
L
Site 56
Y622
V
P
Q
S
A
P
M
Y
Q
Y
L
D
R
K
L
Site 57
Y624
Q
S
A
P
M
Y
Q
Y
L
D
R
K
L
F
K
Site 58
S680
R
Y
L
E
L
I
S
S
I
E
E
R
K
K
R
Site 59
T690
E
R
K
K
R
G
E
T
N
N
D
L
F
L
A
Site 60
Y713
F
H
E
A
A
K
L
Y
K
R
S
G
H
E
N
Site 61
S741
Y
A
K
D
F
L
G
S
G
D
P
K
E
T
K
Site 62
S820
T
Y
L
K
K
L
D
S
P
G
Y
A
A
E
T
Site 63
Y823
K
K
L
D
S
P
G
Y
A
A
E
T
Y
L
K
Site 64
Y828
P
G
Y
A
A
E
T
Y
L
K
M
G
D
L
K
Site 65
Y865
P
E
F
K
D
D
I
Y
M
P
Y
A
Q
W
L
Site 66
Y916
S
R
F
N
D
A
A
Y
Y
Y
W
M
L
S
M
Site 67
Y917
R
F
N
D
A
A
Y
Y
Y
W
M
L
S
M
Q
Site 68
T937
Q
D
P
A
Q
K
D
T
M
L
G
K
F
Y
H
Site 69
Y952
F
Q
R
L
A
E
L
Y
H
G
Y
H
A
I
H
Site 70
Y955
L
A
E
L
Y
H
G
Y
H
A
I
H
R
H
T
Site 71
T962
Y
H
A
I
H
R
H
T
E
D
P
F
S
V
H
Site 72
S967
R
H
T
E
D
P
F
S
V
H
R
P
E
T
L
Site 73
T973
F
S
V
H
R
P
E
T
L
F
N
I
S
R
F
Site 74
S984
I
S
R
F
L
L
H
S
L
P
K
D
T
P
S
Site 75
T989
L
H
S
L
P
K
D
T
P
S
G
I
S
K
V
Site 76
S991
S
L
P
K
D
T
P
S
G
I
S
K
V
K
I
Site 77
T1001
S
K
V
K
I
L
F
T
L
A
K
Q
S
K
A
Site 78
S1006
L
F
T
L
A
K
Q
S
K
A
L
G
A
Y
R
Site 79
Y1019
Y
R
L
A
R
H
A
Y
D
K
L
R
G
L
Y
Site 80
Y1026
Y
D
K
L
R
G
L
Y
I
P
A
R
F
Q
K
Site 81
S1050
R
A
K
P
F
H
D
S
E
E
L
V
P
L
C
Site 82
Y1058
E
E
L
V
P
L
C
Y
R
C
S
T
N
N
P
Site 83
T1062
P
L
C
Y
R
C
S
T
N
N
P
L
L
N
N
Site 84
T1103
F
Y
L
E
E
G
I
T
D
E
E
A
I
S
L
Site 85
S1143
R
L
V
E
T
K
D
S
I
G
D
E
D
P
F
Site 86
T1151
I
G
D
E
D
P
F
T
A
K
L
S
F
E
Q
Site 87
S1155
D
P
F
T
A
K
L
S
F
E
Q
G
G
S
E
Site 88
S1175
V
S
R
L
V
L
R
S
M
S
R
R
D
V
L
Site 89
S1177
R
L
V
L
R
S
M
S
R
R
D
V
L
I
K
Site 90
Y1194
P
P
P
L
R
W
Q
Y
F
R
S
L
L
P
D
Site 91
S1197
L
R
W
Q
Y
F
R
S
L
L
P
D
A
S
I
Site 92
Y1219
Q
M
F
H
S
E
D
Y
E
L
L
V
L
Q
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation