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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOX3
Full Name:
NADPH oxidase 3
Alias:
Mitogenic oxidase 2;gp91phox homolog 3
Type:
Mass (Da):
64935
Number AA:
568
UniProt ID:
Q9HBY0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y32
Y
L
F
I
D
T
F
Y
W
Y
E
E
E
E
S
Site 2
Y42
E
E
E
E
S
F
H
Y
T
R
V
I
L
G
S
Site 3
T43
E
E
E
S
F
H
Y
T
R
V
I
L
G
S
T
Site 4
Y127
H
F
F
N
L
E
R
Y
H
W
S
Q
S
E
E
Site 5
S130
N
L
E
R
Y
H
W
S
Q
S
E
E
A
Q
G
Site 6
S132
E
R
Y
H
W
S
Q
S
E
E
A
Q
G
L
L
Site 7
S143
Q
G
L
L
A
A
L
S
K
L
G
N
T
P
N
Site 8
T148
A
L
S
K
L
G
N
T
P
N
E
S
Y
L
N
Site 9
Y153
G
N
T
P
N
E
S
Y
L
N
P
V
R
T
F
Site 10
T159
S
Y
L
N
P
V
R
T
F
P
T
N
T
T
T
Site 11
T230
G
R
I
V
R
G
Q
T
Q
D
S
L
S
L
H
Site 12
S233
V
R
G
Q
T
Q
D
S
L
S
L
H
N
I
T
Site 13
S235
G
Q
T
Q
D
S
L
S
L
H
N
I
T
F
C
Site 14
T240
S
L
S
L
H
N
I
T
F
C
R
D
R
Y
A
Site 15
Y246
I
T
F
C
R
D
R
Y
A
E
W
Q
T
V
A
Site 16
S261
Q
C
P
V
P
Q
F
S
G
K
E
P
S
A
W
Site 17
T339
S
L
E
W
H
P
F
T
L
T
S
A
P
Q
E
Site 18
T341
E
W
H
P
F
T
L
T
S
A
P
Q
E
D
F
Site 19
S350
A
P
Q
E
D
F
F
S
V
H
I
R
A
A
G
Site 20
S379
Q
A
L
Q
E
P
W
S
L
P
R
L
A
V
D
Site 21
S426
K
S
I
W
Y
K
C
S
E
A
Q
T
P
L
K
Site 22
T430
Y
K
C
S
E
A
Q
T
P
L
K
L
S
K
V
Site 23
Y438
P
L
K
L
S
K
V
Y
F
Y
W
I
C
R
D
Site 24
S464
L
S
L
E
T
R
M
S
E
Q
G
K
T
H
F
Site 25
T469
R
M
S
E
Q
G
K
T
H
F
L
S
Y
H
I
Site 26
T497
A
L
H
W
D
E
N
T
D
V
I
T
G
L
K
Site 27
T507
I
T
G
L
K
Q
K
T
F
Y
G
R
P
N
W
Site 28
Y509
G
L
K
Q
K
T
F
Y
G
R
P
N
W
N
N
Site 29
Y523
N
E
F
K
Q
I
A
Y
N
H
P
S
S
S
I
Site 30
Y551
L
Q
K
M
C
H
L
Y
S
S
A
D
P
R
G
Site 31
S552
Q
K
M
C
H
L
Y
S
S
A
D
P
R
G
V
Site 32
S553
K
M
C
H
L
Y
S
S
A
D
P
R
G
V
H
Site 33
Y562
D
P
R
G
V
H
F
Y
Y
N
K
E
S
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation