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Updated November 2019
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Protein Info
Short Name:
TANC2
Full Name:
Protein TANC2
Alias:
Ankyrin-repeat protein; DKFZP564D166; FLJ10215; FLJ11824; KIAA1148; KIAA1636; Rolling pebbles B; Rols; ROLSA; Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Type:
Mass (Da):
219650
Number AA:
1990
UniProt ID:
Q9HCD6
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0005488
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
N
S
L
K
M
L
L
T
G
G
K
S
S
R
K
Site 2
S15
M
L
L
T
G
G
K
S
S
R
K
N
R
S
S
Site 3
S16
L
L
T
G
G
K
S
S
R
K
N
R
S
S
D
Site 4
S21
K
S
S
R
K
N
R
S
S
D
G
G
S
E
E
Site 5
S22
S
S
R
K
N
R
S
S
D
G
G
S
E
E
P
Site 6
S26
N
R
S
S
D
G
G
S
E
E
P
P
D
R
R
Site 7
S35
E
P
P
D
R
R
Q
S
S
V
D
S
R
Q
S
Site 8
S36
P
P
D
R
R
Q
S
S
V
D
S
R
Q
S
R
Site 9
S39
R
R
Q
S
S
V
D
S
R
Q
S
R
S
G
Q
Site 10
S42
S
S
V
D
S
R
Q
S
R
S
G
Q
G
G
I
Site 11
S44
V
D
S
R
Q
S
R
S
G
Q
G
G
I
S
T
Site 12
T51
S
G
Q
G
G
I
S
T
E
S
D
C
A
F
E
Site 13
S53
Q
G
G
I
S
T
E
S
D
C
A
F
E
P
D
Site 14
S69
A
V
P
P
L
P
V
S
E
G
D
A
E
Q
E
Site 15
S82
Q
E
L
G
P
P
P
S
V
D
E
A
A
N
T
Site 16
Y111
E
V
Q
P
G
D
Q
Y
S
M
E
V
Q
D
E
Site 17
S112
V
Q
P
G
D
Q
Y
S
M
E
V
Q
D
E
N
Site 18
S122
V
Q
D
E
N
Q
T
S
A
I
T
Q
R
I
S
Site 19
T125
E
N
Q
T
S
A
I
T
Q
R
I
S
P
C
S
Site 20
S129
S
A
I
T
Q
R
I
S
P
C
S
T
L
T
S
Site 21
S132
T
Q
R
I
S
P
C
S
T
L
T
S
S
T
A
Site 22
T133
Q
R
I
S
P
C
S
T
L
T
S
S
T
A
S
Site 23
T135
I
S
P
C
S
T
L
T
S
S
T
A
S
P
P
Site 24
S136
S
P
C
S
T
L
T
S
S
T
A
S
P
P
A
Site 25
S137
P
C
S
T
L
T
S
S
T
A
S
P
P
A
S
Site 26
T138
C
S
T
L
T
S
S
T
A
S
P
P
A
S
S
Site 27
S140
T
L
T
S
S
T
A
S
P
P
A
S
S
P
C
Site 28
S144
S
T
A
S
P
P
A
S
S
P
C
S
T
L
P
Site 29
S145
T
A
S
P
P
A
S
S
P
C
S
T
L
P
P
Site 30
S148
P
P
A
S
S
P
C
S
T
L
P
P
I
S
T
Site 31
T149
P
A
S
S
P
C
S
T
L
P
P
I
S
T
N
Site 32
S154
C
S
T
L
P
P
I
S
T
N
A
T
A
K
D
Site 33
T158
P
P
I
S
T
N
A
T
A
K
D
C
S
Y
G
Site 34
Y164
A
T
A
K
D
C
S
Y
G
A
V
T
S
P
T
Site 35
S169
C
S
Y
G
A
V
T
S
P
T
S
T
L
E
S
Site 36
T171
Y
G
A
V
T
S
P
T
S
T
L
E
S
R
D
Site 37
S172
G
A
V
T
S
P
T
S
T
L
E
S
R
D
S
Site 38
T173
A
V
T
S
P
T
S
T
L
E
S
R
D
S
G
Site 39
S176
S
P
T
S
T
L
E
S
R
D
S
G
I
I
A
Site 40
S179
S
T
L
E
S
R
D
S
G
I
I
A
T
L
T
Site 41
T184
R
D
S
G
I
I
A
T
L
T
S
Y
S
E
N
Site 42
T186
S
G
I
I
A
T
L
T
S
Y
S
E
N
V
E
Site 43
S189
I
A
T
L
T
S
Y
S
E
N
V
E
R
T
K
Site 44
Y197
E
N
V
E
R
T
K
Y
A
G
E
S
S
K
E
Site 45
S201
R
T
K
Y
A
G
E
S
S
K
E
L
G
S
G
Site 46
S202
T
K
Y
A
G
E
S
S
K
E
L
G
S
G
G
Site 47
S207
E
S
S
K
E
L
G
S
G
G
N
I
K
P
W
Site 48
S216
G
N
I
K
P
W
Q
S
Q
K
S
S
M
D
S
Site 49
S219
K
P
W
Q
S
Q
K
S
S
M
D
S
C
L
Y
Site 50
S220
P
W
Q
S
Q
K
S
S
M
D
S
C
L
Y
R
Site 51
S223
S
Q
K
S
S
M
D
S
C
L
Y
R
V
D
E
Site 52
Y226
S
S
M
D
S
C
L
Y
R
V
D
E
N
M
T
Site 53
S238
N
M
T
A
S
T
Y
S
L
N
K
I
P
E
R
Site 54
T249
I
P
E
R
N
L
E
T
V
L
S
Q
S
V
Q
Site 55
S252
R
N
L
E
T
V
L
S
Q
S
V
Q
S
I
P
Site 56
Y261
S
V
Q
S
I
P
L
Y
L
M
P
R
P
N
S
Site 57
S268
Y
L
M
P
R
P
N
S
V
A
A
T
S
S
A
Site 58
T272
R
P
N
S
V
A
A
T
S
S
A
H
L
E
D
Site 59
Y282
A
H
L
E
D
L
A
Y
L
D
E
Q
R
H
T
Site 60
T289
Y
L
D
E
Q
R
H
T
P
L
R
T
S
L
R
Site 61
S294
R
H
T
P
L
R
T
S
L
R
M
P
R
Q
S
Site 62
S301
S
L
R
M
P
R
Q
S
M
G
G
A
R
T
Q
Site 63
Y318
L
R
V
R
F
A
P
Y
R
P
P
D
I
S
L
Site 64
S324
P
Y
R
P
P
D
I
S
L
K
P
L
L
F
E
Site 65
S357
E
I
D
A
Q
L
Q
S
S
N
A
S
V
N
Q
Site 66
S358
I
D
A
Q
L
Q
S
S
N
A
S
V
N
Q
G
Site 67
S361
Q
L
Q
S
S
N
A
S
V
N
Q
G
V
V
I
Site 68
T391
V
A
L
S
C
H
G
T
R
M
R
Q
I
A
S
Site 69
S398
T
R
M
R
Q
I
A
S
D
S
P
H
A
S
P
Site 70
S400
M
R
Q
I
A
S
D
S
P
H
A
S
P
K
H
Site 71
S404
A
S
D
S
P
H
A
S
P
K
H
V
D
A
N
Site 72
T417
A
N
R
E
L
P
L
T
Q
P
P
S
A
H
S
Site 73
S421
L
P
L
T
Q
P
P
S
A
H
S
S
I
T
S
Site 74
S424
T
Q
P
P
S
A
H
S
S
I
T
S
G
S
C
Site 75
S425
Q
P
P
S
A
H
S
S
I
T
S
G
S
C
P
Site 76
T427
P
S
A
H
S
S
I
T
S
G
S
C
P
G
T
Site 77
S428
S
A
H
S
S
I
T
S
G
S
C
P
G
T
P
Site 78
S430
H
S
S
I
T
S
G
S
C
P
G
T
P
E
M
Site 79
T434
T
S
G
S
C
P
G
T
P
E
M
R
R
R
Q
Site 80
S450
E
A
M
R
R
L
A
S
Q
V
V
A
Y
H
Y
Site 81
Y464
Y
C
Q
A
D
N
A
Y
T
C
L
V
P
E
F
Site 82
T486
L
C
R
S
P
Q
L
T
A
Y
R
E
Q
L
L
Site 83
Y488
R
S
P
Q
L
T
A
Y
R
E
Q
L
L
R
E
Site 84
S500
L
R
E
P
H
L
Q
S
M
L
S
L
R
S
C
Site 85
S503
P
H
L
Q
S
M
L
S
L
R
S
C
V
Q
D
Site 86
S514
C
V
Q
D
P
M
A
S
F
R
R
G
V
L
E
Site 87
Y554
A
E
F
H
K
P
D
Y
G
D
T
I
V
S
F
Site 88
T557
H
K
P
D
Y
G
D
T
I
V
S
F
L
S
K
Site 89
S620
Y
I
L
H
R
I
H
S
S
S
E
I
Q
N
N
Site 90
S622
L
H
R
I
H
S
S
S
E
I
Q
N
N
I
S
Site 91
S629
S
E
I
Q
N
N
I
S
L
N
G
K
M
D
N
Site 92
T637
L
N
G
K
M
D
N
T
T
F
G
K
L
S
S
Site 93
T638
N
G
K
M
D
N
T
T
F
G
K
L
S
S
H
Site 94
S643
N
T
T
F
G
K
L
S
S
H
L
K
T
L
S
Site 95
S644
T
T
F
G
K
L
S
S
H
L
K
T
L
S
Q
Site 96
T648
K
L
S
S
H
L
K
T
L
S
Q
G
S
Y
L
Site 97
S650
S
S
H
L
K
T
L
S
Q
G
S
Y
L
Y
L
Site 98
Y654
K
T
L
S
Q
G
S
Y
L
Y
L
K
L
T
F
Site 99
S673
K
G
Y
L
V
L
K
S
S
S
Y
K
V
V
P
Site 100
T697
Q
C
N
M
K
F
P
T
Q
S
S
F
D
R
V
Site 101
S699
N
M
K
F
P
T
Q
S
S
F
D
R
V
M
P
Site 102
S700
M
K
F
P
T
Q
S
S
F
D
R
V
M
P
L
Site 103
T735
N
A
G
S
I
E
G
T
L
E
W
E
D
F
Q
Site 104
S749
Q
Q
R
M
E
N
L
S
M
F
L
I
K
R
R
Site 105
T759
L
I
K
R
R
D
M
T
R
M
F
V
H
P
S
Site 106
T780
W
R
E
E
G
E
K
T
K
F
L
C
D
P
R
Site 107
T809
G
K
L
N
R
Q
Q
T
I
E
L
G
H
H
I
Site 108
S844
Q
G
L
W
I
S
Y
S
T
E
G
L
S
M
A
Site 109
S849
S
Y
S
T
E
G
L
S
M
A
L
A
S
L
R
Site 110
Y859
L
A
S
L
R
N
L
Y
T
P
N
I
K
V
S
Site 111
T860
A
S
L
R
N
L
Y
T
P
N
I
K
V
S
R
Site 112
Y878
L
G
G
A
N
I
N
Y
R
T
E
V
L
N
N
Site 113
S914
F
G
A
N
V
D
A
S
S
E
S
G
L
T
P
Site 114
S915
G
A
N
V
D
A
S
S
E
S
G
L
T
P
L
Site 115
S988
Q
Q
G
V
F
K
K
S
H
A
I
Q
Q
A
L
Site 116
Y1009
G
Y
T
E
I
V
S
Y
L
L
D
L
P
E
K
Site 117
S1028
V
E
R
A
Q
I
N
S
F
D
S
L
W
G
E
Site 118
S1031
A
Q
I
N
S
F
D
S
L
W
G
E
T
A
L
Site 119
T1039
L
W
G
E
T
A
L
T
A
A
A
G
R
G
K
Site 120
S1073
R
G
A
V
P
L
F
S
T
V
R
Q
G
H
W
Site 121
T1074
G
A
V
P
L
F
S
T
V
R
Q
G
H
W
Q
Site 122
T1102
M
A
D
K
Q
G
R
T
P
L
M
M
A
A
S
Site 123
S1138
K
E
G
L
T
A
L
S
W
A
C
L
K
G
H
Site 124
S1147
A
C
L
K
G
H
L
S
V
V
R
S
L
V
D
Site 125
S1151
G
H
L
S
V
V
R
S
L
V
D
N
G
A
A
Site 126
T1159
L
V
D
N
G
A
A
T
D
H
A
D
K
N
G
Site 127
T1168
H
A
D
K
N
G
R
T
P
L
D
L
A
A
F
Site 128
Y1197
A
M
I
E
H
V
D
Y
S
G
M
R
P
L
D
Site 129
T1217
R
N
T
S
V
V
V
T
L
L
K
K
G
A
K
Site 130
T1229
G
A
K
I
G
P
A
T
W
A
M
A
T
S
K
Site 131
Y1255
M
E
E
G
D
M
F
Y
K
K
G
K
V
K
E
Site 132
Y1269
E
A
A
Q
R
Y
Q
Y
A
L
K
K
F
P
R
Site 133
T1285
G
F
G
E
D
L
K
T
F
R
E
L
K
V
S
Site 134
S1298
V
S
L
L
L
N
L
S
R
C
R
R
K
M
N
Site 135
T1315
G
M
A
E
E
F
A
T
K
A
L
E
L
K
P
Site 136
S1324
A
L
E
L
K
P
K
S
Y
E
A
Y
Y
A
R
Site 137
Y1328
K
P
K
S
Y
E
A
Y
Y
A
R
A
R
A
K
Site 138
Y1329
P
K
S
Y
E
A
Y
Y
A
R
A
R
A
K
R
Site 139
S1337
A
R
A
R
A
K
R
S
S
R
Q
F
A
A
A
Site 140
S1338
R
A
R
A
K
R
S
S
R
Q
F
A
A
A
L
Site 141
Y1405
E
P
Q
H
E
D
I
Y
S
V
Q
D
I
F
E
Site 142
S1406
P
Q
H
E
D
I
Y
S
V
Q
D
I
F
E
E
Site 143
Y1415
Q
D
I
F
E
E
E
Y
L
E
Q
D
V
E
N
Site 144
S1434
L
Q
T
E
A
R
P
S
Q
G
L
P
V
I
Q
Site 145
S1442
Q
G
L
P
V
I
Q
S
P
P
S
S
P
P
H
Site 146
S1445
P
V
I
Q
S
P
P
S
S
P
P
H
R
D
S
Site 147
S1446
V
I
Q
S
P
P
S
S
P
P
H
R
D
S
A
Site 148
S1452
S
S
P
P
H
R
D
S
A
Y
I
S
S
S
P
Site 149
Y1454
P
P
H
R
D
S
A
Y
I
S
S
S
P
L
G
Site 150
S1456
H
R
D
S
A
Y
I
S
S
S
P
L
G
S
H
Site 151
S1457
R
D
S
A
Y
I
S
S
S
P
L
G
S
H
Q
Site 152
S1458
D
S
A
Y
I
S
S
S
P
L
G
S
H
Q
V
Site 153
S1462
I
S
S
S
P
L
G
S
H
Q
V
F
D
F
R
Site 154
S1470
H
Q
V
F
D
F
R
S
S
S
S
V
G
S
P
Site 155
S1471
Q
V
F
D
F
R
S
S
S
S
V
G
S
P
T
Site 156
S1472
V
F
D
F
R
S
S
S
S
V
G
S
P
T
R
Site 157
S1473
F
D
F
R
S
S
S
S
V
G
S
P
T
R
Q
Site 158
S1476
R
S
S
S
S
V
G
S
P
T
R
Q
T
Y
Q
Site 159
T1481
V
G
S
P
T
R
Q
T
Y
Q
S
T
S
P
A
Site 160
Y1482
G
S
P
T
R
Q
T
Y
Q
S
T
S
P
A
L
Site 161
S1484
P
T
R
Q
T
Y
Q
S
T
S
P
A
L
S
P
Site 162
S1486
R
Q
T
Y
Q
S
T
S
P
A
L
S
P
T
H
Site 163
S1490
Q
S
T
S
P
A
L
S
P
T
H
Q
N
S
H
Site 164
T1492
T
S
P
A
L
S
P
T
H
Q
N
S
H
Y
R
Site 165
S1496
L
S
P
T
H
Q
N
S
H
Y
R
P
S
P
P
Site 166
Y1498
P
T
H
Q
N
S
H
Y
R
P
S
P
P
H
T
Site 167
S1501
Q
N
S
H
Y
R
P
S
P
P
H
T
S
P
A
Site 168
T1505
Y
R
P
S
P
P
H
T
S
P
A
H
Q
G
G
Site 169
S1506
R
P
S
P
P
H
T
S
P
A
H
Q
G
G
S
Site 170
S1513
S
P
A
H
Q
G
G
S
Y
R
F
S
P
P
P
Site 171
Y1514
P
A
H
Q
G
G
S
Y
R
F
S
P
P
P
V
Site 172
S1517
Q
G
G
S
Y
R
F
S
P
P
P
V
G
G
Q
Site 173
Y1528
V
G
G
Q
G
K
E
Y
P
S
P
P
P
S
P
Site 174
S1530
G
Q
G
K
E
Y
P
S
P
P
P
S
P
L
R
Site 175
S1534
E
Y
P
S
P
P
P
S
P
L
R
R
G
P
Q
Site 176
Y1542
P
L
R
R
G
P
Q
Y
R
A
S
P
P
A
E
Site 177
S1545
R
G
P
Q
Y
R
A
S
P
P
A
E
S
M
S
Site 178
S1550
R
A
S
P
P
A
E
S
M
S
V
Y
R
S
Q
Site 179
S1552
S
P
P
A
E
S
M
S
V
Y
R
S
Q
S
G
Site 180
Y1554
P
A
E
S
M
S
V
Y
R
S
Q
S
G
S
P
Site 181
S1556
E
S
M
S
V
Y
R
S
Q
S
G
S
P
V
R
Site 182
S1558
M
S
V
Y
R
S
Q
S
G
S
P
V
R
Y
Q
Site 183
S1560
V
Y
R
S
Q
S
G
S
P
V
R
Y
Q
Q
E
Site 184
Y1564
Q
S
G
S
P
V
R
Y
Q
Q
E
T
S
V
S
Site 185
T1568
P
V
R
Y
Q
Q
E
T
S
V
S
Q
L
P
G
Site 186
S1569
V
R
Y
Q
Q
E
T
S
V
S
Q
L
P
G
R
Site 187
S1571
Y
Q
Q
E
T
S
V
S
Q
L
P
G
R
P
K
Site 188
S1579
Q
L
P
G
R
P
K
S
P
L
S
K
M
A
Q
Site 189
S1582
G
R
P
K
S
P
L
S
K
M
A
Q
R
P
Y
Site 190
Y1589
S
K
M
A
Q
R
P
Y
Q
M
P
Q
L
P
V
Site 191
S1615
A
K
A
Q
I
V
R
S
N
Q
P
S
P
A
V
Site 192
S1619
I
V
R
S
N
Q
P
S
P
A
V
H
S
S
T
Site 193
S1624
Q
P
S
P
A
V
H
S
S
T
V
I
P
T
G
Site 194
Y1633
T
V
I
P
T
G
A
Y
G
Q
V
A
H
S
M
Site 195
S1639
A
Y
G
Q
V
A
H
S
M
A
S
K
Y
Q
S
Site 196
S1642
Q
V
A
H
S
M
A
S
K
Y
Q
S
S
Q
G
Site 197
Y1644
A
H
S
M
A
S
K
Y
Q
S
S
Q
G
D
I
Site 198
S1646
S
M
A
S
K
Y
Q
S
S
Q
G
D
I
G
V
Site 199
S1647
M
A
S
K
Y
Q
S
S
Q
G
D
I
G
V
S
Site 200
S1654
S
Q
G
D
I
G
V
S
Q
S
R
L
V
Y
Q
Site 201
S1656
G
D
I
G
V
S
Q
S
R
L
V
Y
Q
G
S
Site 202
S1682
Q
H
V
Q
A
S
L
S
A
G
A
I
C
Q
H
Site 203
S1702
E
D
L
P
Q
R
P
S
S
A
Y
R
G
G
V
Site 204
S1703
D
L
P
Q
R
P
S
S
A
Y
R
G
G
V
R
Site 205
Y1705
P
Q
R
P
S
S
A
Y
R
G
G
V
R
Y
S
Site 206
Y1711
A
Y
R
G
G
V
R
Y
S
Q
T
P
Q
I
G
Site 207
S1712
Y
R
G
G
V
R
Y
S
Q
T
P
Q
I
G
R
Site 208
T1714
G
G
V
R
Y
S
Q
T
P
Q
I
G
R
S
Q
Site 209
S1720
Q
T
P
Q
I
G
R
S
Q
S
A
S
Y
Y
P
Site 210
S1722
P
Q
I
G
R
S
Q
S
A
S
Y
Y
P
V
C
Site 211
S1724
I
G
R
S
Q
S
A
S
Y
Y
P
V
C
H
S
Site 212
Y1725
G
R
S
Q
S
A
S
Y
Y
P
V
C
H
S
K
Site 213
Y1726
R
S
Q
S
A
S
Y
Y
P
V
C
H
S
K
L
Site 214
S1738
S
K
L
D
L
E
R
S
S
S
Q
L
G
S
P
Site 215
S1739
K
L
D
L
E
R
S
S
S
Q
L
G
S
P
D
Site 216
S1740
L
D
L
E
R
S
S
S
Q
L
G
S
P
D
V
Site 217
S1744
R
S
S
S
Q
L
G
S
P
D
V
S
H
L
I
Site 218
S1748
Q
L
G
S
P
D
V
S
H
L
I
R
R
P
I
Site 219
S1756
H
L
I
R
R
P
I
S
V
N
P
N
E
I
K
Site 220
T1768
E
I
K
P
H
P
P
T
P
R
P
L
L
H
S
Site 221
S1775
T
P
R
P
L
L
H
S
Q
S
V
G
L
R
F
Site 222
S1777
R
P
L
L
H
S
Q
S
V
G
L
R
F
S
P
Site 223
S1783
Q
S
V
G
L
R
F
S
P
S
S
N
S
I
S
Site 224
S1785
V
G
L
R
F
S
P
S
S
N
S
I
S
S
T
Site 225
S1786
G
L
R
F
S
P
S
S
N
S
I
S
S
T
S
Site 226
S1788
R
F
S
P
S
S
N
S
I
S
S
T
S
N
L
Site 227
S1790
S
P
S
S
N
S
I
S
S
T
S
N
L
T
P
Site 228
S1791
P
S
S
N
S
I
S
S
T
S
N
L
T
P
T
Site 229
T1792
S
S
N
S
I
S
S
T
S
N
L
T
P
T
F
Site 230
T1796
I
S
S
T
S
N
L
T
P
T
F
R
P
S
S
Site 231
T1798
S
T
S
N
L
T
P
T
F
R
P
S
S
S
I
Site 232
S1802
L
T
P
T
F
R
P
S
S
S
I
Q
Q
M
E
Site 233
S1803
T
P
T
F
R
P
S
S
S
I
Q
Q
M
E
I
Site 234
S1804
P
T
F
R
P
S
S
S
I
Q
Q
M
E
I
P
Site 235
Y1816
E
I
P
L
K
P
A
Y
E
R
S
C
D
E
L
Site 236
S1819
L
K
P
A
Y
E
R
S
C
D
E
L
S
P
V
Site 237
S1824
E
R
S
C
D
E
L
S
P
V
S
P
T
Q
G
Site 238
S1827
C
D
E
L
S
P
V
S
P
T
Q
G
G
Y
P
Site 239
Y1833
V
S
P
T
Q
G
G
Y
P
S
E
P
T
R
S
Site 240
S1835
P
T
Q
G
G
Y
P
S
E
P
T
R
S
R
T
Site 241
T1838
G
G
Y
P
S
E
P
T
R
S
R
T
T
P
F
Site 242
S1840
Y
P
S
E
P
T
R
S
R
T
T
P
F
M
G
Site 243
T1842
S
E
P
T
R
S
R
T
T
P
F
M
G
I
I
Site 244
T1843
E
P
T
R
S
R
T
T
P
F
M
G
I
I
D
Site 245
Y1858
K
T
A
R
T
Q
Q
Y
P
H
L
H
Q
Q
N
Site 246
T1867
H
L
H
Q
Q
N
R
T
W
A
V
S
S
V
D
Site 247
S1871
Q
N
R
T
W
A
V
S
S
V
D
T
V
L
S
Site 248
S1872
N
R
T
W
A
V
S
S
V
D
T
V
L
S
P
Site 249
S1878
S
S
V
D
T
V
L
S
P
T
S
P
G
N
L
Site 250
S1881
D
T
V
L
S
P
T
S
P
G
N
L
P
Q
P
Site 251
S1890
G
N
L
P
Q
P
E
S
F
S
P
P
S
S
I
Site 252
S1892
L
P
Q
P
E
S
F
S
P
P
S
S
I
S
N
Site 253
S1895
P
E
S
F
S
P
P
S
S
I
S
N
I
A
F
Site 254
S1896
E
S
F
S
P
P
S
S
I
S
N
I
A
F
Y
Site 255
S1898
F
S
P
P
S
S
I
S
N
I
A
F
Y
N
K
Site 256
Y1919
G
H
L
L
E
D
D
Y
Y
S
P
H
G
M
L
Site 257
Y1920
H
L
L
E
D
D
Y
Y
S
P
H
G
M
L
A
Site 258
S1921
L
L
E
D
D
Y
Y
S
P
H
G
M
L
A
N
Site 259
S1930
H
G
M
L
A
N
G
S
R
G
D
L
L
E
R
Site 260
S1939
G
D
L
L
E
R
V
S
Q
A
S
S
Y
P
D
Site 261
S1942
L
E
R
V
S
Q
A
S
S
Y
P
D
V
K
V
Site 262
S1943
E
R
V
S
Q
A
S
S
Y
P
D
V
K
V
A
Site 263
Y1944
R
V
S
Q
A
S
S
Y
P
D
V
K
V
A
R
Site 264
Y1959
T
L
P
V
A
Q
A
Y
Q
D
N
L
Y
R
Q
Site 265
Y1964
Q
A
Y
Q
D
N
L
Y
R
Q
L
S
R
D
S
Site 266
S1968
D
N
L
Y
R
Q
L
S
R
D
S
R
Q
G
Q
Site 267
S1971
Y
R
Q
L
S
R
D
S
R
Q
G
Q
T
S
P
Site 268
S1977
D
S
R
Q
G
Q
T
S
P
I
K
P
K
R
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation